| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0884223 |
| B2M | beta-2-microglobulin | 0.0599643 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.052516 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0504428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0492953 |
| SDC4 | syndecan 4 | 0.0463998 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0438985 |
| CANX | calnexin | 0.0356382 |
| VEGFA | vascular endothelial growth factor A | 0.0288553 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0286869 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0285733 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.021464 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0212889 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.021091 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0210431 |
| KYNU | kynureninase | 0.0199712 |
| FAM13A | family with sequence similarity 13, member A | 0.0196478 |
| PRELID2 | PRELI domain containing 2 | 0.0193723 |
| GOLGB1 | golgin B1 | 0.0190938 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0180496 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0175929 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0175201 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0173762 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0171952 |
| HYOU1 | hypoxia up-regulated 1 | 0.0167011 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0166907 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0166085 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0164417 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0164063 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.016368 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0159395 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0158046 |
| PGM3 | phosphoglucomutase 3 | 0.0157983 |
| MCL1 | myeloid cell leukemia 1 | 0.0156075 |
| PLEC | plectin | 0.015597 |
| ANXA1 | annexin A1 | 0.015583 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0155328 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0153594 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0152086 |
| RPL37A | ribosomal protein L37a | 0.0150796 |
| YEATS2 | YEATS domain containing 2 | 0.0145708 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0145173 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0144454 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0142199 |
| MATR3 | matrin 3 | 0.0140905 |
| HDAC9 | histone deacetylase 9 | 0.0140445 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0138748 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0138451 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0136985 |
| INSIG2 | insulin induced gene 2 | 0.0136684 |
| OGA | O-GlcNAcase | 0.0135055 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0133033 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0133024 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0131936 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0131592 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0131202 |
| UBN2 | ubinuclein 2 | 0.0131038 |
| TPM3 | tropomyosin 3 | 0.0130808 |
| ANXA2 | annexin A2 | 0.0130661 |
| FNIP1 | folliculin interacting protein 1 | 0.0129031 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0127752 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0127184 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0127013 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0125945 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0125889 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.012507 |
| FAM107B | family with sequence similarity 107, member B | 0.0123992 |
| YBX1 | Y box binding protein 1 | 0.0123651 |
| SEC24A | SEC24 family member A | 0.0123329 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0122384 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0122233 |
| SUCO | SUN domain containing ossification factor | 0.0120888 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0118321 |
| AHR | aryl hydrocarbon receptor | 0.0118243 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0117763 |
| SERINC1 | serine incorporator 1 | 0.0116619 |
| RND3 | Rho family GTPase 3 | 0.0116492 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0116317 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0115935 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0115916 |
| SPAG9 | sperm associated antigen 9 | 0.011434 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0114054 |
| CLINT1 | clathrin interactor 1 | 0.0113211 |
| MYOF | myoferlin | 0.0112245 |
| ARRDC3 | arrestin domain containing 3 | 0.0112161 |
| EXOC4 | exocyst complex component 4 | 0.0111775 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0110251 |
| SDCBP | syndecan binding protein (syntenin) | 0.0110025 |
| SQSTM1 | sequestosome 1 | 0.0109832 |
| HBP1 | HMG-box transcription factor 1 | 0.010841 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0108407 |
| USP53 | ubiquitin specific peptidase 53 | 0.0108322 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0107767 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0107392 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0106755 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0106649 |
| ANLN | anillin, actin binding protein | 0.0106412 |
| CD47 | CD47 molecule | 0.0106372 |
| BRD2 | bromodomain containing 2 | 0.0106125 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0106125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131914 |
| TMSB10 | thymosin beta 10 | -0.0889187 |
| FN1 | fibronectin 1 | -0.0888799 |
| MT2A | metallothionein 2A | -0.0805472 |
| COL1A1 | collagen, type I, alpha 1 | -0.0647154 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0590021 |
| VIM | vimentin | -0.0589969 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0525982 |
| COL1A2 | collagen, type I, alpha 2 | -0.0465965 |
| MT1X | metallothionein 1X | -0.0406124 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0389839 |
| PRSS23 | protease, serine, 23 | -0.0338366 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0328357 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0317082 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.03056 |
| HMGA2 | high mobility group AT-hook 2 | -0.0303068 |
| MAP1B | microtubule-associated protein 1B | -0.0295231 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0294034 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0266096 |
| TNS3 | tensin 3 | -0.0265918 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0263331 |
| RRBP1 | ribosome binding protein 1 | -0.0255982 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0244461 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.024155 |
| ACTG1 | actin gamma 1 | -0.0240629 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0238723 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0238588 |
| NDRG1 | N-myc downstream regulated 1 | -0.023708 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0228133 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0227114 |
| CCNI | cyclin I | -0.0226611 |
| GLIS3 | GLIS family zinc finger 3 | -0.0218534 |
| EGR1 | early growth response 1 | -0.0218129 |
| TNNC1 | troponin C type 1 (slow) | -0.0206502 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.020606 |
| TPM1 | tropomyosin 1 (alpha) | -0.0195708 |
| RPL28 | ribosomal protein L28 | -0.0194021 |
| COL5A2 | collagen, type V, alpha 2 | -0.0192714 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0178375 |
| S100A9 | S100 calcium binding protein A9 | -0.0178066 |
| GNAS | GNAS complex locus | -0.0177208 |
| LOX | lysyl oxidase | -0.0173752 |
| RPS14 | ribosomal protein S14 | -0.017104 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0170406 |
| TUBB | tubulin, beta class I | -0.0169277 |
| COL5A1 | collagen, type V, alpha 1 | -0.0168308 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0167646 |
| PGK1 | phosphoglycerate kinase 1 | -0.0164039 |
| TPM4 | tropomyosin 4 | -0.0162392 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0161839 |
| TAGLN2 | transgelin 2 | -0.0157965 |
| RAI14 | retinoic acid induced 14 | -0.0155357 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0155259 |
| RPL34 | ribosomal protein L34 | -0.0154223 |
| PTMA | prothymosin, alpha | -0.0150189 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0147701 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0147101 |
| PKM | pyruvate kinase, muscle | -0.0144345 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0143823 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0143706 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0143518 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0142358 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0141314 |
| CST3 | cystatin C | -0.0140945 |
| TUBA1B | tubulin, alpha 1b | -0.0139536 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0135292 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0134852 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0134588 |
| RUNX1 | runt-related transcription factor 1 | -0.0134039 |
| HMGB1 | high mobility group box 1 | -0.0132101 |
| BSG | basigin (Ok blood group) | -0.0129321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.012901 |
| PFN1 | profilin 1 | -0.012898 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0128066 |
| CBX3 | chromobox homolog 3 | -0.0127552 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0126665 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0126617 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0124274 |
| POTEF | POTE ankyrin domain family, member F | -0.0121062 |
| RPL31 | ribosomal protein L31 | -0.0120173 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0120124 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0119074 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0115991 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0114966 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0114892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0114078 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0113212 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.011199 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0110613 |
| SERF2 | small EDRK-rich factor 2 | -0.011034 |
| RPL32 | ribosomal protein L32 | -0.0109528 |
| EFHD2 | EF-hand domain family, member D2 | -0.0108782 |
| FLOT1 | flotillin 1 | -0.010835 |
| MAP4 | microtubule-associated protein 4 | -0.0107773 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0107667 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0107165 |
| TNPO1 | transportin 1 | -0.0105839 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0104809 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0104341 |
| TMEM123 | transmembrane protein 123 | -0.0103883 |
