| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0880796 |
| SMAD3 | SMAD family member 3 | 0.0685692 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0641891 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0635252 |
| HMGA2 | high mobility group AT-hook 2 | 0.0607147 |
| SVIL | supervillin | 0.0575538 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0535471 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0494436 |
| FMNL2 | formin-like 2 | 0.0483612 |
| INTS6 | integrator complex subunit 6 | 0.046557 |
| AHNAK | AHNAK nucleoprotein | 0.0431093 |
| PRKCA | protein kinase C, alpha | 0.0401191 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0397801 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.03891 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0385958 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0380914 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.037862 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0378515 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0365415 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0362736 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0354673 |
| COL5A1 | collagen, type V, alpha 1 | 0.0354036 |
| ASPH | aspartate beta-hydroxylase | 0.035023 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.034859 |
| SMYD3 | SET and MYND domain containing 3 | 0.0345103 |
| ANGPTL4 | angiopoietin-like 4 | 0.0314416 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311401 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0310371 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303384 |
| MYO10 | myosin X | 0.0303046 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0295014 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0291398 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0279932 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0272129 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0269386 |
| DST | dystonin | 0.0262968 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0262895 |
| NAV2 | neuron navigator 2 | 0.0261986 |
| ANO6 | anoctamin 6 | 0.0258861 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0257776 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0256297 |
| PRELID2 | PRELI domain containing 2 | 0.0252178 |
| SKIL | SKI-like proto-oncogene | 0.0250575 |
| GPR39 | G protein-coupled receptor 39 | 0.0250569 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0248439 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0240485 |
| CCND1 | cyclin D1 | 0.0237856 |
| EXT1 | exostosin glycosyltransferase 1 | 0.022977 |
| PTGES2 | prostaglandin E synthase 2 | 0.0228022 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.022735 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0222698 |
| RORA | RAR-related orphan receptor A | 0.0219794 |
| RAD51B | RAD51 paralog B | 0.0215639 |
| MCL1 | myeloid cell leukemia 1 | 0.0215435 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0213321 |
| SDC2 | syndecan 2 | 0.0211578 |
| DIAPH1 | diaphanous-related formin 1 | 0.0210184 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0209332 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0206889 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0203439 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0202074 |
| MSI2 | musashi RNA-binding protein 2 | 0.0199067 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0197301 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0196389 |
| EHBP1 | EH domain binding protein 1 | 0.0195719 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.019454 |
| SEPTIN9 | septin 9 | 0.0192887 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0192632 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0192456 |
| SLMAP | sarcolemma associated protein | 0.0191339 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0189415 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0189215 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0188725 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0187514 |
| PTK2 | protein tyrosine kinase 2 | 0.0186742 |
| RAI14 | retinoic acid induced 14 | 0.0186718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0183566 |
| TPM3 | tropomyosin 3 | 0.018319 |
| RUNX1 | runt-related transcription factor 1 | 0.0180979 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0180703 |
| SLC38A2 | solute carrier family 38, member 2 | 0.017993 |
| BRD2 | bromodomain containing 2 | 0.0179823 |
| NAV1 | neuron navigator 1 | 0.0179778 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0179734 |
| SUMF1 | sulfatase modifying factor 1 | 0.0179436 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0179282 |
| SATB2 | SATB homeobox 2 | 0.0179258 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0177747 |
| GOLGB1 | golgin B1 | 0.0177071 |
| EP300 | E1A binding protein p300 | 0.0176686 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0174166 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0173566 |
| TNRC18 | trinucleotide repeat containing 18 | 0.017275 |
| NIBAN2 | niban apoptosis regulator 2 | 0.017244 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0171971 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0171755 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0171432 |
| ATXN7L1 | ataxin 7-like 1 | 0.0170728 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0169021 |
| CPNE1 | copine I | 0.0167237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18914 |
| PTMA | prothymosin, alpha | -0.104312 |
| TMSB10 | thymosin beta 10 | -0.0930151 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0746888 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0643608 |
| VIM | vimentin | -0.0620619 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0490678 |
| NKTR | natural killer cell triggering receptor | -0.0487122 |
| IGF2 | insulin-like growth factor 2 | -0.045902 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0446292 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0435377 |
| MED13 | mediator complex subunit 13 | -0.04318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426076 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.042567 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0425186 |
| SPAG9 | sperm associated antigen 9 | -0.0412743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0400815 |
| TPX2 | TPX2, microtubule-associated | -0.0396643 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0376337 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0363927 |
| CENPF | centromere protein F, 350/400kDa | -0.035994 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.03586 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.035647 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0353309 |
| DNER | delta/notch-like EGF repeat containing | -0.034517 |
| TXNIP | thioredoxin interacting protein | -0.0344525 |
| EGR1 | early growth response 1 | -0.033219 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0323312 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.03175 |
| YBX3 | Y box binding protein 3 | -0.0317006 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0313214 |
| TXNRD1 | thioredoxin reductase 1 | -0.0311742 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0309928 |
| RPL19 | ribosomal protein L19 | -0.0306816 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302587 |
| COPA | coatomer protein complex, subunit alpha | -0.0301331 |
| SEC24A | SEC24 family member A | -0.0298405 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0294475 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0293843 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0289912 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0289362 |
| ATM | ATM serine/threonine kinase | -0.0286022 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0285338 |
| GOLGA4 | golgin A4 | -0.028417 |
| DIAPH3 | diaphanous-related formin 3 | -0.0283688 |
| SRPK2 | SRSF protein kinase 2 | -0.0275956 |
| RBM39 | RNA binding motif protein 39 | -0.0274959 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.027211 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0271529 |
| ZNF609 | zinc finger protein 609 | -0.0271335 |
| RPS23 | ribosomal protein S23 | -0.0270666 |
| SEPTIN7 | septin 7 | -0.0269955 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.02686 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0266327 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0265157 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0264588 |
| NF1 | neurofibromin 1 | -0.0263438 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262748 |
| PFN1 | profilin 1 | -0.0262128 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0262006 |
| CCDC88A | coiled-coil domain containing 88A | -0.0259838 |
| MT2A | metallothionein 2A | -0.0259692 |
| RDX | radixin | -0.025873 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0257258 |
| RPLP0 | ribosomal protein, large, P0 | -0.025605 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.025165 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0247614 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0244955 |
| CD44 | CD44 molecule (Indian blood group) | -0.0243601 |
| TMEM263 | transmembrane protein 263 | -0.0241766 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | -0.0236836 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0233414 |
| RNF145 | ring finger protein 145 | -0.0232122 |
| SNX14 | sorting nexin 14 | -0.0231554 |
| MORF4L2 | mortality factor 4 like 2 | -0.0230521 |
| RPL12 | ribosomal protein L12 | -0.022826 |
| TPI1 | triosephosphate isomerase 1 | -0.0227946 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0227353 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0226392 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0223725 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0220012 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0218408 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0218188 |
| RPS6 | ribosomal protein S6 | -0.0218155 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0217419 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0217131 |
| NUP58 | nucleoporin 58 | -0.0216427 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0215953 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0214622 |
| S100A9 | S100 calcium binding protein A9 | -0.0212453 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0211655 |
| TPM4 | tropomyosin 4 | -0.0211523 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0209605 |
| RPL11 | ribosomal protein L11 | -0.0206464 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0206293 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0205043 |
| TUT4 | terminal uridylyl transferase 4 | -0.0203363 |
| YY1 | YY1 transcription factor | -0.020334 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0200961 |
| RAI1 | retinoic acid induced 1 | -0.0199844 |
