| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.151891 |
| B2M | beta-2-microglobulin | 0.141199 |
| EXT1 | exostosin glycosyltransferase 1 | 0.141127 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.125487 |
| TMEM156 | transmembrane protein 156 | 0.121382 |
| VEGFA | vascular endothelial growth factor A | 0.110226 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.105352 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0973844 |
| SFTPA2 | surfactant protein A2 | 0.0878086 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0805927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0751082 |
| STC2 | stanniocalcin 2 | 0.0746962 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0736903 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0711045 |
| POTEF | POTE ankyrin domain family, member F | 0.070658 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0679598 |
| TPM3 | tropomyosin 3 | 0.0671689 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0667325 |
| ANKRD28 | ankyrin repeat domain 28 | 0.066485 |
| EFNA5 | ephrin-A5 | 0.064791 |
| NRP1 | neuropilin 1 | 0.0607574 |
| SVIL | supervillin | 0.0604053 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0582157 |
| TXNRD1 | thioredoxin reductase 1 | 0.0567703 |
| ENO1 | enolase 1, (alpha) | 0.056726 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.056709 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0566238 |
| NTN4 | netrin 4 | 0.0562988 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0559238 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0557892 |
| GPATCH2L | G patch domain containing 2-like | 0.0544758 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0531999 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0522629 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0521542 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0521064 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0515835 |
| MAP1B | microtubule-associated protein 1B | 0.0513651 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0510822 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0506587 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0500112 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0492707 |
| SMAD3 | SMAD family member 3 | 0.0486035 |
| SEPTIN9 | septin 9 | 0.0485188 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0476713 |
| PALLD | palladin, cytoskeletal associated protein | 0.0467485 |
| RPL37A | ribosomal protein L37a | 0.0466337 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0463618 |
| RPS12 | ribosomal protein S12 | 0.0455798 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0449181 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0439947 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0439694 |
| TPM4 | tropomyosin 4 | 0.0438115 |
| RPL37 | ribosomal protein L37 | 0.0436047 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0435848 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0427775 |
| TOP1 | topoisomerase (DNA) I | 0.0426572 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0425678 |
| FAT1 | FAT atypical cadherin 1 | 0.0420919 |
| GOLGA4 | golgin A4 | 0.0420229 |
| APP | amyloid beta (A4) precursor protein | 0.041459 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0411921 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0411647 |
| RACK1 | receptor for activated C kinase 1 | 0.041086 |
| JMJD1C | jumonji domain containing 1C | 0.0408667 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0405077 |
| RASAL2 | RAS protein activator like 2 | 0.0399314 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0394837 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0391848 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0391466 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0385908 |
| EGFR | epidermal growth factor receptor | 0.0383577 |
| EREG | epiregulin | 0.0379828 |
| RAB10 | RAB10, member RAS oncogene family | 0.037858 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0378559 |
| SIK3 | SIK family kinase 3 | 0.0377867 |
| KLHL5 | kelch-like family member 5 | 0.0369991 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0368398 |
| MCL1 | myeloid cell leukemia 1 | 0.0367515 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0366631 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0365562 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0365528 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0358175 |
| RPL31 | ribosomal protein L31 | 0.0357919 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0357181 |
| DSTN | destrin (actin depolymerizing factor) | 0.035516 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0354426 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353832 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.03503 |
| ATXN1 | ataxin 1 | 0.0347903 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0344091 |
| SMYD3 | SET and MYND domain containing 3 | 0.0342075 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0335835 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0335307 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0334828 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0331804 |
| LOXL2 | lysyl oxidase-like 2 | 0.03315 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0331391 |
| FOXP1 | forkhead box P1 | 0.0331356 |
| RND3 | Rho family GTPase 3 | 0.0330429 |
| LDHA | lactate dehydrogenase A | 0.0328995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.153146 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131327 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122574 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0780749 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0751977 |
| NDRG1 | N-myc downstream regulated 1 | -0.0663928 |
| NRG1 | neuregulin 1 | -0.0644961 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.062408 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0545367 |
| CADM1 | cell adhesion molecule 1 | -0.0462479 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0452435 |
| H1-0 | H1.0 linker histone | -0.0446716 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0444607 |
| HMGA2 | high mobility group AT-hook 2 | -0.0441396 |
| AEBP2 | AE binding protein 2 | -0.0401423 |
| GNAS | GNAS complex locus | -0.0397776 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0389686 |
| FAM20C | family with sequence similarity 20, member C | -0.0369461 |
| OGA | O-GlcNAcase | -0.0364736 |
| ITGA1 | integrin, alpha 1 | -0.0356712 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0354202 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0350885 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0334041 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0326482 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324152 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0321674 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0316387 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309232 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0302738 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.028935 |
| RBM39 | RNA binding motif protein 39 | -0.0287137 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0285191 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0280128 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0279881 |
| ACTN4 | actinin, alpha 4 | -0.0276004 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274745 |
| SQSTM1 | sequestosome 1 | -0.0272776 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0269858 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.025629 |
| LRRC23 | leucine rich repeat containing 23 | -0.0256217 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0253118 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.024587 |
| HELZ | helicase with zinc finger | -0.0243973 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239985 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0239509 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0238641 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0238164 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0236771 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0234054 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233769 |
| TENM4 | teneurin transmembrane protein 4 | -0.0233204 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0232238 |
| RRBP1 | ribosome binding protein 1 | -0.0225632 |
| USP3 | ubiquitin specific peptidase 3 | -0.0224443 |
| MIS18BP1 | MIS18 binding protein 1 | -0.022411 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0221739 |
| COLEC11 | collectin sub-family member 11 | -0.0221167 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0218654 |
| INTS6 | integrator complex subunit 6 | -0.0216479 |
| RHEB | Ras homolog enriched in brain | -0.0215485 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0214423 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0212724 |
| SPAG9 | sperm associated antigen 9 | -0.0212637 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0212555 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0211343 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0209459 |
| NKTR | natural killer cell triggering receptor | -0.0206707 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0205695 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.020424 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0203872 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0199987 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0193561 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0193252 |
| CENPF | centromere protein F, 350/400kDa | -0.0192871 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0192534 |
| CERT1 | ceramide transporter 1 | -0.0191623 |
| NABP1 | nucleic acid binding protein 1 | -0.018892 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.018855 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0187078 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.018698 |
| KLHL24 | kelch-like family member 24 | -0.0186566 |
| RTN3 | reticulon 3 | -0.0185838 |
| SEPTIN7 | septin 7 | -0.0183761 |
| MORF4L2 | mortality factor 4 like 2 | -0.0183021 |
| DENND4C | DENN/MADD domain containing 4C | -0.0179965 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.017973 |
| ETV6 | ets variant 6 | -0.0179503 |
| DIAPH3 | diaphanous-related formin 3 | -0.0179016 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0178727 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0178139 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0177186 |
| HBP1 | HMG-box transcription factor 1 | -0.0176665 |
| CFAP20DC | CFAP20 domain containing | -0.0176298 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0175248 |
| GOLGA7B | golgin A7 family, member B | -0.0175119 |
| TFRC | transferrin receptor | -0.0174701 |
| TFG | TRK-fused gene | -0.0174588 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0174232 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0173489 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0173249 |
