Teratoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A germ cell and embryonal cancer that is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers. (Human Disease Ontology, DOID_3307)
External Link https://www.disgenet.org/browser/0/1/0/C0039538
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Genes

159 genes associated with the disease Teratoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAT1 acetyl-CoA acetyltransferase 1
AFP alpha-fetoprotein
ALPG alkaline phosphatase, germ cell
ALPP alkaline phosphatase, placental
AQP4 aquaporin 4
AR androgen receptor
ASXL3 additional sex combs like transcriptional regulator 3
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATOH8 atonal homolog 8 (Drosophila)
BAX BCL2-associated X protein
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CALD1 caldesmon 1
CBX3 chromobox homolog 3
CBX5 chromobox homolog 5
CD1A CD1a molecule
CD34 CD34 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX2 caudal type homeobox 2
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CHD7 chromodomain helicase DNA binding protein 7
CISH cytokine inducible SH2-containing protein
CKAP4 cytoskeleton-associated protein 4
CREG1 cellular repressor of E1A-stimulated genes 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAZL deleted in azoospermia-like
DCDC2 doublecortin domain containing 2
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DHCR24 24-dehydrocholesterol reductase
DMRT1 doublesex and mab-3 related transcription factor 1
DND1 DND microRNA-mediated repression inhibitor 1
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
EGR1 early growth response 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EPCAM epithelial cell adhesion molecule
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
ESRP1 epithelial splicing regulatory protein 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FMOD fibromodulin
FOXO3 forkhead box O3
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA2 GATA binding protein 2
GATA6 GATA binding protein 6
GDNF glial cell derived neurotrophic factor
GFI1B growth factor independent 1B transcription repressor
GFRA1 GDNF family receptor alpha 1
GMNN geminin, DNA replication inhibitor
GPC4 glypican 4
GRN granulin
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HPSE heparanase
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL3 interleukin 3
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
ITFG1 integrin alpha FG-GAP repeat containing 1
JAG2 jagged 2
KAT5 K(lysine) acetyltransferase 5
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLHL1 kelch-like family member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT10 keratin 10, type I
KRT18 keratin 18, type I
LHX2 LIM homeobox 2
LIN28A lin-28 homolog A (C. elegans)
LNPEP leucyl/cystinyl aminopeptidase
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAK16 MAK16 homolog (S. cerevisiae)
MAT1A methionine adenosyltransferase I, alpha
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEFV Mediterranean fever
MESD mesoderm development LRP chaperone
METTL8 methyltransferase like 8
MKS1 Meckel syndrome, type 1
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MRC1 mannose receptor, C type 1
MSC musculin
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NANOG Nanog homeobox
NANOS3 nanos homolog 3 (Drosophila)
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NKX2-1 NK2 homeobox 1
NOG noggin
NOTCH1 notch 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
PGM1 phosphoglucomutase 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAA phospholipase A2-activating protein
PLSCR4 phospholipid scramblase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
POU5F1 POU class 5 homeobox 1
PRDM14 PR domain containing 14
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RBMS3 RNA binding motif, single stranded interacting protein 3
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
RPE65 retinal pigment epithelium-specific protein 65kDa
SETBP1 SET binding protein 1
SIRT1 sirtuin 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAI1 snail family zinc finger 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX2 SRY (sex determining region Y)-box 2
SRRM2 serine/arginine repetitive matrix 2
SRY sex determining region Y
SSTR2 somatostatin receptor 2
STK11 serine/threonine kinase 11
SYCE1L synaptonemal complex central element protein 1-like
TCF12 transcription factor 12
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIPRL TOR signaling pathway regulator
TP53 tumor protein p53
TP63 tumor protein p63
TRRAP transformation/transcription domain-associated protein
UTF1 undifferentiated embryonic cell transcription factor 1
UVRAG UV radiation resistance associated
ZEB1 zinc finger E-box binding homeobox 1
ZFP42 ZFP42 zinc finger protein