| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/1549008 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Terbinafine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQLE | squalene epoxidase | 0.95 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.69 |
| ZNF274 | zinc finger protein 274 | 0.62 |
| TRIM62 | tripartite motif containing 62 | 0.58 |
| WRB | tryptophan rich basic protein | 0.57 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.56 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.55 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.48 |
| SFXN4 | sideroflexin 4 | 0.47 |
| BTBD11 | BTB (POZ) domain containing 11 | 0.46 |
| ATP13A2 | ATPase type 13A2 | 0.42 |
| ZNF362 | zinc finger protein 362 | 0.42 |
| USP27X | ubiquitin specific peptidase 27, X-linked | 0.4 |
| DMTN | dematin actin binding protein | 0.39 |
| ZNF761 | zinc finger protein 761 | 0.39 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.37 |
| C2CD4C | C2 calcium-dependent domain containing 4C | 0.36 |
| GLMP | glycosylated lysosomal membrane protein | 0.35 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.35 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.35 |
| NMU | neuromedin U | 0.33 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.33 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.33 |
| COPRS | coordinator of PRMT5, differentiation stimulator | 0.32 |
| BCOR | BCL6 corepressor | 0.32 |
| CRY2 | cryptochrome circadian clock 2 | 0.32 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.31 |
| ZNF480 | zinc finger protein 480 | 0.31 |
| GID4 | GID complex subunit 4 | 0.3 |
| SLC16A6 | solute carrier family 16, member 6 | 0.3 |
| RNF220 | ring finger protein 220 | 0.3 |
| MYO18B | myosin XVIIIB | 0.3 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.29 |
| BCLAF3 | BCLAF1 and THRAP3 family member 3 | 0.29 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.29 |
| TJP1 | tight junction protein 1 | 0.29 |
| HOXA10 | homeobox A10 | 0.29 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.29 |
| FAM20C | family with sequence similarity 20, member C | 0.28 |
| TMC4 | transmembrane channel-like 4 | 0.27 |
| FAM241A | family with sequence similarity 241 member A | 0.27 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.27 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.27 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.26 |
| CCDC57 | coiled-coil domain containing 57 | 0.26 |
| SMIM12 | small integral membrane protein 12 | 0.26 |
| CHCHD1 | coiled-coil-helix-coiled-coil-helix domain containing 1 | 0.26 |
| TMEM97 | transmembrane protein 97 | 0.26 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | 0.26 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.26 |
| FIZ1 | FLT3-interacting zinc finger 1 | 0.26 |
| MICB | MHC class I polypeptide-related sequence B | 0.26 |
| GPR179 | G protein-coupled receptor 179 | 0.26 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 0.25 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.25 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.25 |
| LAMC3 | laminin, gamma 3 | 0.25 |
| GPSM2 | G-protein signaling modulator 2 | 0.25 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit | 0.25 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.24 |
| MIIP | migration and invasion inhibitory protein | 0.24 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.24 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.24 |
| ERICH5 | glutamate-rich 5 | 0.24 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 0.24 |
| OBSL1 | obscurin-like 1 | 0.24 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | 0.24 |
| ABHD14A | abhydrolase domain containing 14A | 0.24 |
| CALU | calumenin | 0.24 |
| ABITRAM | actin binding transcription modulator | 0.24 |
| TBX3 | T-box 3 | 0.23 |
| OPHN1 | oligophrenin 1 | 0.23 |
| KLHL9 | kelch-like family member 9 | 0.23 |
| RNF145 | ring finger protein 145 | 0.23 |
| SLC38A2 | solute carrier family 38, member 2 | 0.23 |
| SLC2A4RG | SLC2A4 regulator | 0.23 |
| UPP1 | uridine phosphorylase 1 | 0.23 |
| MYLK | myosin light chain kinase | 0.23 |
| ZNF227 | zinc finger protein 227 | 0.23 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.23 |
| ZBTB7B | zinc finger and BTB domain containing 7B | 0.22 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.22 |
| ZNF440 | zinc finger protein 440 | 0.22 |
| SHROOM3 | shroom family member 3 | 0.22 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.22 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.22 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.22 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.22 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.22 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | 0.22 |
| MSANTD4 | Myb/SANT-like DNA-binding domain containing 4 with coiled-coils | 0.22 |
| FAM133B | family with sequence similarity 133, member B | 0.22 |
| ZBED6 | zinc finger, BED-type containing 6 | 0.21 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | 0.21 |
| TREX1 | three prime repair exonuclease 1 | 0.21 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 | 0.21 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | 0.21 |
| FAM120C | family with sequence similarity 120C | 0.2 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.2 |
| KMT5B | lysine methyltransferase 5B | 0.2 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -1.15 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.89 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | -0.86 |
| FAM241B | family with sequence similarity 241 member B | -0.82 |
| FN1 | fibronectin 1 | -0.82 |
| SBSN | suprabasin | -0.78 |
| FGB | fibrinogen beta chain | -0.75 |
| SGSH | N-sulfoglucosamine sulfohydrolase | -0.66 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.65 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | -0.62 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.62 |
| RPL26 | ribosomal protein L26 | -0.6 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.59 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.55 |
| ANGPTL4 | angiopoietin-like 4 | -0.5 |
| PRKCH | protein kinase C, eta | -0.49 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | -0.48 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.47 |
| TMEM64 | transmembrane protein 64 | -0.46 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 | -0.46 |
| PITX1 | paired-like homeodomain 1 | -0.43 |
| GORASP1 | golgi reassembly stacking protein 1, 65kDa | -0.42 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.42 |
| ATXN7L3B | ataxin 7-like 3B | -0.41 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.41 |
| SET | SET nuclear proto-oncogene | -0.4 |
| COL1A1 | collagen, type I, alpha 1 | -0.4 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | -0.39 |
| ZNF219 | zinc finger protein 219 | -0.39 |
| SCAND1 | SCAN domain containing 1 | -0.38 |
| SLC25A46 | solute carrier family 25, member 46 | -0.37 |
| ERCC8 | excision repair cross-complementation group 8 | -0.37 |
| TGDS | TDP-glucose 4,6-dehydratase | -0.37 |
| SORT1 | sortilin 1 | -0.36 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.36 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.35 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.35 |
| MED12L | mediator complex subunit 12-like | -0.35 |
| ADIPOR1 | adiponectin receptor 1 | -0.34 |
| ABHD4 | abhydrolase domain containing 4 | -0.34 |
| CFAP57 | cilia and flagella associated protein 57 | -0.33 |
| BCO2 | beta-carotene oxygenase 2 | -0.33 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.32 |
| ZNF160 | zinc finger protein 160 | -0.32 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.32 |
| C2CD3 | C2 calcium-dependent domain containing 3 | -0.32 |
| HEXD | hexosaminidase D | -0.31 |
| NUDT14 | nudix (nucleoside diphosphate linked moiety X)-type motif 14 | -0.31 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) | -0.31 |
| PLXNB1 | plexin B1 | -0.31 |
| MT1F | metallothionein 1F | -0.31 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | -0.31 |
| ZNF282 | zinc finger protein 282 | -0.3 |
| SPATA31D1 | SPATA31 subfamily D, member 1 | -0.3 |
| ZBTB45 | zinc finger and BTB domain containing 45 | -0.3 |
| ISL2 | ISL LIM homeobox 2 | -0.29 |
| ONECUT2 | one cut homeobox 2 | -0.29 |
| ZDHHC12 | zinc finger, DHHC-type containing 12 | -0.29 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.29 |
| USP46 | ubiquitin specific peptidase 46 | -0.28 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -0.28 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.28 |
| EME1 | essential meiotic structure-specific endonuclease 1 | -0.28 |
| PET100 | PET100 homolog (S. cerevisiae) | -0.28 |
| NLGN2 | neuroligin 2 | -0.28 |
| MROH6 | maestro heat-like repeat family member 6 | -0.28 |
| LRRCC1 | leucine rich repeat and coiled-coil centrosomal protein 1 | -0.28 |
| ZNF581 | zinc finger protein 581 | -0.27 |
| ZNF205 | zinc finger protein 205 | -0.27 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.27 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 | -0.27 |
| BBS1 | Bardet-Biedl syndrome 1 | -0.26 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.26 |
| SLC22A23 | solute carrier family 22, member 23 | -0.26 |
| TOB1 | transducer of ERBB2, 1 | -0.26 |
| COQ4 | coenzyme Q4 | -0.25 |
| ZNF354B | zinc finger protein 354B | -0.25 |
| TP53I11 | tumor protein p53 inducible protein 11 | -0.25 |
| RNF7 | ring finger protein 7 | -0.25 |
| DBNL | drebrin-like | -0.25 |
| HLA-F | major histocompatibility complex, class I, F | -0.25 |
| MR1 | major histocompatibility complex, class I-related | -0.25 |
| TOX2 | TOX high mobility group box family member 2 | -0.24 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.24 |
| ZNF576 | zinc finger protein 576 | -0.24 |
| MKRN1 | makorin ring finger protein 1 | -0.24 |
| UBOX5 | U-box domain containing 5 | -0.24 |
| MT1X | metallothionein 1X | -0.24 |
| MAGEF1 | melanoma antigen family F1 | -0.24 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.24 |
| PEX7 | peroxisomal biogenesis factor 7 | -0.24 |
| LACTB2 | lactamase, beta 2 | -0.24 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | -0.23 |
| ATP5IF1 | ATP synthase inhibitory factor subunit 1 | -0.23 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.23 |
| EPHX4 | epoxide hydrolase 4 | -0.23 |
| TRIM15 | tripartite motif containing 15 | -0.23 |
| ABHD17C | abhydrolase domain containing 17C | -0.23 |
| LMTK2 | lemur tyrosine kinase 2 | -0.23 |
| DNASE1L1 | deoxyribonuclease I-like 1 | -0.23 |
