| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.151255 |
| VIM | vimentin | 0.140519 |
| MT2A | metallothionein 2A | 0.132128 |
| TMSB10 | thymosin beta 10 | 0.126326 |
| NDRG1 | N-myc downstream regulated 1 | 0.105269 |
| PLAT | plasminogen activator, tissue | 0.0947142 |
| CD44 | CD44 molecule (Indian blood group) | 0.062519 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0589912 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0519306 |
| LOX | lysyl oxidase | 0.0491608 |
| FLNA | filamin A, alpha | 0.0443179 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0440721 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0434111 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0429728 |
| CALR | calreticulin | 0.0421385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0417121 |
| PODXL | podocalyxin-like | 0.0407197 |
| RPL37A | ribosomal protein L37a | 0.0369943 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0360834 |
| NAV2 | neuron navigator 2 | 0.0358333 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0322868 |
| HLA-B | major histocompatibility complex, class I, B | 0.0320147 |
| L1CAM | L1 cell adhesion molecule | 0.030955 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.029773 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0288747 |
| KLF6 | Kruppel-like factor 6 | 0.0280618 |
| C1D | C1D nuclear receptor corepressor | 0.0277659 |
| RPS3 | ribosomal protein S3 | 0.0269724 |
| PFN1 | profilin 1 | 0.0264714 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0264288 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0260387 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0251495 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0250107 |
| RPL23 | ribosomal protein L23 | 0.0250103 |
| B2M | beta-2-microglobulin | 0.0249032 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0247406 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0238588 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0233538 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0229503 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0225423 |
| RPS12 | ribosomal protein S12 | 0.0221807 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0217156 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0206108 |
| ATXN1 | ataxin 1 | 0.0204109 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0203839 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0202336 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0200295 |
| RACK1 | receptor for activated C kinase 1 | 0.0197337 |
| RPL35A | ribosomal protein L35a | 0.0196655 |
| MKI67 | marker of proliferation Ki-67 | 0.0195352 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0194842 |
| RPL26 | ribosomal protein L26 | 0.019391 |
| ATP13A3 | ATPase type 13A3 | 0.0193822 |
| ERBIN | erbb2 interacting protein | 0.0193636 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0192932 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0191656 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0190926 |
| RPS8 | ribosomal protein S8 | 0.0187407 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0187241 |
| NUP58 | nucleoporin 58 | 0.0185812 |
| MYADM | myeloid-associated differentiation marker | 0.0183905 |
| RPS17 | ribosomal protein S17 | 0.0181958 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0181591 |
| NOTCH2 | notch 2 | 0.0180933 |
| SFTPA2 | surfactant protein A2 | 0.0179796 |
| S100A6 | S100 calcium binding protein A6 | 0.0174159 |
| RPL37 | ribosomal protein L37 | 0.0171416 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0168071 |
| CENPF | centromere protein F, 350/400kDa | 0.0166803 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0166521 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0163013 |
| ZNF148 | zinc finger protein 148 | 0.0162135 |
| TPR | translocated promoter region, nuclear basket protein | 0.0160797 |
| S100A11 | S100 calcium binding protein A11 | 0.0158708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0158479 |
| ACTG1 | actin gamma 1 | 0.0158049 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0157284 |
| RPL36 | ribosomal protein L36 | 0.0156759 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0156627 |
| MT1X | metallothionein 1X | 0.0156265 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.015446 |
| SET | SET nuclear proto-oncogene | 0.015382 |
| FAM107B | family with sequence similarity 107, member B | 0.0151793 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0150999 |
| RPS19 | ribosomal protein S19 | 0.0150739 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0149742 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0149273 |
| ITSN2 | intersectin 2 | 0.0148392 |
| RPS2 | ribosomal protein S2 | 0.0147858 |
| RPL31 | ribosomal protein L31 | 0.0145014 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0144672 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0144479 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0143451 |
| FTL | ferritin, light polypeptide | 0.0142851 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0142523 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0141713 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.014013 |
| RPLP1 | ribosomal protein, large, P1 | 0.0138327 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0136673 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0136224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.179396 |
| AHNAK | AHNAK nucleoprotein | -0.174957 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.125591 |
| COL5A1 | collagen, type V, alpha 1 | -0.122233 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.11445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105624 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.101675 |
| FN1 | fibronectin 1 | -0.0955231 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0939263 |
| NAV1 | neuron navigator 1 | -0.0913137 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0901985 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0766734 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0766338 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0740093 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0739836 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0739251 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0720855 |
| RIGI | RNA sensor RIG-I | -0.07035 |
| CANX | calnexin | -0.0595114 |
| COL5A2 | collagen, type V, alpha 2 | -0.059238 |
| MX2 | MX dynamin-like GTPase 2 | -0.0559659 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0516684 |
| MAP1B | microtubule-associated protein 1B | -0.0515992 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0499137 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0494365 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0443056 |
| FBN1 | fibrillin 1 | -0.0437596 |
| TPM1 | tropomyosin 1 (alpha) | -0.0424092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0418969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.041634 |
| MYOF | myoferlin | -0.0407556 |
| FSTL1 | follistatin-like 1 | -0.0398565 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0375357 |
| TNS3 | tensin 3 | -0.0355838 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0349201 |
| SQSTM1 | sequestosome 1 | -0.0344686 |
| CDH13 | cadherin 13 | -0.0341078 |
| VCL | vinculin | -0.0331275 |
| SUCNR1 | succinate receptor 1 | -0.0325866 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0324737 |
| CUX1 | cut-like homeobox 1 | -0.0322543 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0320756 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0317289 |
| MEIS2 | Meis homeobox 2 | -0.0314916 |
| AUTS2 | autism susceptibility candidate 2 | -0.0314861 |
| MED13L | mediator complex subunit 13-like | -0.0306327 |
| PRSS23 | protease, serine, 23 | -0.0299385 |
| IL7R | interleukin 7 receptor | -0.029289 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0288767 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0287332 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0285413 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0279143 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0277906 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0276528 |
| FRMD4A | FERM domain containing 4A | -0.0272569 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0270835 |
| SP100 | SP100 nuclear antigen | -0.0270733 |
| POTEF | POTE ankyrin domain family, member F | -0.0266293 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0266232 |
| JAZF1 | JAZF zinc finger 1 | -0.026148 |
| ANXA2 | annexin A2 | -0.0259756 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0258837 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0258227 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0256004 |
| LRRC17 | leucine rich repeat containing 17 | -0.0250702 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249988 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0249877 |
| PLXNA2 | plexin A2 | -0.0246217 |
| COL1A2 | collagen, type I, alpha 2 | -0.0245173 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0244187 |
| PCDH7 | protocadherin 7 | -0.0243445 |
| DST | dystonin | -0.0243229 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0241913 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0241308 |
| TENM3 | teneurin transmembrane protein 3 | -0.023882 |
| RUNX1 | runt-related transcription factor 1 | -0.023717 |
| AEBP2 | AE binding protein 2 | -0.0236758 |
| VEGFA | vascular endothelial growth factor A | -0.0236013 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0235576 |
| IPO9 | importin 9 | -0.0229968 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0228465 |
| TPM4 | tropomyosin 4 | -0.0222293 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0221723 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0217361 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0216209 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0215572 |
| RAD51B | RAD51 paralog B | -0.0208821 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0204813 |
| TAGLN2 | transgelin 2 | -0.0204798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0202404 |
| MSI2 | musashi RNA-binding protein 2 | -0.0201761 |
| TMSB4X | thymosin beta 4, X-linked | -0.0201689 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0192669 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0190881 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0189895 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0187881 |
| COL1A1 | collagen, type I, alpha 1 | -0.0187017 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0186791 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.018414 |
| GOLGB1 | golgin B1 | -0.0183853 |
