| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.431726 |
| VCL | vinculin | 0.0996992 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0915241 |
| PLAT | plasminogen activator, tissue | 0.0689606 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0596018 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0534931 |
| NDRG1 | N-myc downstream regulated 1 | 0.0534763 |
| STC1 | stanniocalcin 1 | 0.0517296 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0514073 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0463155 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0458166 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0430781 |
| PCBP2 | poly(rC) binding protein 2 | 0.042943 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0412334 |
| RPL37A | ribosomal protein L37a | 0.0411578 |
| TLE4 | transducin-like enhancer of split 4 | 0.0398553 |
| BPTF | bromodomain PHD finger transcription factor | 0.0389463 |
| PRKCA | protein kinase C, alpha | 0.0387675 |
| GPC5 | glypican 5 | 0.0386968 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0382465 |
| MCL1 | myeloid cell leukemia 1 | 0.0369151 |
| DIAPH2 | diaphanous-related formin 2 | 0.0365856 |
| VMP1 | vacuole membrane protein 1 | 0.0358222 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0353708 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0346911 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0343129 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0340985 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0340028 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0339294 |
| INTS6 | integrator complex subunit 6 | 0.0332043 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0327249 |
| GPATCH2L | G patch domain containing 2-like | 0.0322649 |
| ZNF638 | zinc finger protein 638 | 0.032236 |
| ATXN1 | ataxin 1 | 0.0320884 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0314804 |
| VEGFA | vascular endothelial growth factor A | 0.0312999 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0307772 |
| EGR1 | early growth response 1 | 0.0307081 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0299271 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0292192 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0292083 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0291559 |
| HMGA2 | high mobility group AT-hook 2 | 0.0288787 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0284987 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282153 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0280997 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0280879 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0278951 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0276069 |
| PTEN | phosphatase and tensin homolog | 0.0270905 |
| FERMT2 | fermitin family member 2 | 0.0269971 |
| AHR | aryl hydrocarbon receptor | 0.0262742 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0262547 |
| CENPF | centromere protein F, 350/400kDa | 0.0260754 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0259139 |
| RPS12 | ribosomal protein S12 | 0.0252306 |
| FLNB | filamin B, beta | 0.0246582 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0245267 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0244147 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0239826 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0238823 |
| FNIP1 | folliculin interacting protein 1 | 0.0237488 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0237068 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0236461 |
| CDH13 | cadherin 13 | 0.0234384 |
| EXOC4 | exocyst complex component 4 | 0.0233635 |
| ENAH | enabled homolog (Drosophila) | 0.0229157 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0228818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0228038 |
| FN1 | fibronectin 1 | 0.0227521 |
| MYO1E | myosin IE | 0.0227461 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0225961 |
| STK38L | serine/threonine kinase 38 like | 0.0225274 |
| RGS5 | regulator of G-protein signaling 5 | 0.0225074 |
| SNX14 | sorting nexin 14 | 0.0221005 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0220036 |
| JMJD1C | jumonji domain containing 1C | 0.0219949 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0215835 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.02149 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0214808 |
| ACTG1 | actin gamma 1 | 0.0213484 |
| KIAA1217 | KIAA1217 | 0.0210407 |
| USP34 | ubiquitin specific peptidase 34 | 0.0208831 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0206228 |
| GDF15 | growth differentiation factor 15 | 0.0205966 |
| NAV2 | neuron navigator 2 | 0.0205194 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.020448 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0203102 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0201419 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.02012 |
| HOMER1 | homer scaffolding protein 1 | 0.0199618 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0199403 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0196329 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0196149 |
| CCDC88A | coiled-coil domain containing 88A | 0.0195052 |
| GOLGB1 | golgin B1 | 0.019464 |
| L1CAM | L1 cell adhesion molecule | 0.019351 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0191408 |
| SETBP1 | SET binding protein 1 | 0.0191245 |
| PRKCE | protein kinase C, epsilon | 0.0190715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.149372 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119581 |
| PTMA | prothymosin, alpha | -0.0914368 |
| COL1A1 | collagen, type I, alpha 1 | -0.0884876 |
| COL3A1 | collagen, type III, alpha 1 | -0.0845601 |
| LPIN1 | lipin 1 | -0.0756365 |
| FMN1 | formin 1 | -0.0687052 |
| SYT1 | synaptotagmin I | -0.0652968 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0611876 |
| RPS6 | ribosomal protein S6 | -0.0609291 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.050517 |
| NRG1 | neuregulin 1 | -0.0500041 |
| AHNAK | AHNAK nucleoprotein | -0.048804 |
| RPS24 | ribosomal protein S24 | -0.0487162 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469547 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0427318 |
| H3-3B | H3.3 histone B | -0.0426991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0426845 |
| RPL38 | ribosomal protein L38 | -0.0408251 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0404304 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0397669 |
| AOPEP | aminopeptidase O (putative) | -0.0377042 |
| SP100 | SP100 nuclear antigen | -0.0366404 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0357634 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0350536 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0349095 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.034759 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0343697 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0334039 |
| PCDH9 | protocadherin 9 | -0.0328596 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0327791 |
| RPL19 | ribosomal protein L19 | -0.0326723 |
| CCDC47 | coiled-coil domain containing 47 | -0.0325897 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0323958 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.03206 |
| CADM2 | cell adhesion molecule 2 | -0.0318896 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0318768 |
| GNAS | GNAS complex locus | -0.0315544 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0312432 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0311614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.030936 |
| CCND1 | cyclin D1 | -0.0304226 |
| RPL32 | ribosomal protein L32 | -0.0299057 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0298694 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297909 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0293209 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.028484 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0280535 |
| TRIB2 | tribbles pseudokinase 2 | -0.0279873 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0273417 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0268585 |
| RNF213 | ring finger protein 213 | -0.0267718 |
| ZNF804A | zinc finger protein 804A | -0.0264585 |
| MAP1B | microtubule-associated protein 1B | -0.026228 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.026022 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0256745 |
| RPL4 | ribosomal protein L4 | -0.0255997 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0252189 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0250698 |
| RBM39 | RNA binding motif protein 39 | -0.0248438 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0247737 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0245919 |
| CNTN4 | contactin 4 | -0.0245287 |
| FOXK2 | forkhead box K2 | -0.0242587 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0239236 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0238503 |
| WDR45B | WD repeat domain 45B | -0.0238481 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0237126 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0232399 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0231414 |
| UBC | ubiquitin C | -0.0228508 |
| HIP1 | huntingtin interacting protein 1 | -0.0227854 |
| H1-0 | H1.0 linker histone | -0.0226794 |
| WAC | WW domain containing adaptor with coiled-coil | -0.022616 |
| CANX | calnexin | -0.0225534 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0225014 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0224678 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0224193 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0222771 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0222048 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0221723 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0221628 |
| MAP4 | microtubule-associated protein 4 | -0.021839 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0216836 |
| TCERG1 | transcription elongation regulator 1 | -0.0215547 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.021484 |
| KLHL13 | kelch-like family member 13 | -0.0210983 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.020909 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0207954 |
| RPLP0 | ribosomal protein, large, P0 | -0.0207116 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0206256 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.020595 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0203741 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0202878 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0201933 |
| MEIS2 | Meis homeobox 2 | -0.0201457 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0201434 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0201358 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0199534 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.019909 |
