| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.19645 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.110558 |
| MACC1 | metastasis associated in colon cancer 1 | 0.104626 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0850144 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0826315 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0713415 |
| MYO1E | myosin IE | 0.0659852 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0645036 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0593321 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0583009 |
| FTL | ferritin, light polypeptide | 0.0575992 |
| NDRG1 | N-myc downstream regulated 1 | 0.0565446 |
| ZNF292 | zinc finger protein 292 | 0.0557179 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0517504 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.04864 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0486129 |
| TMC5 | transmembrane channel-like 5 | 0.0482268 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0470504 |
| B2M | beta-2-microglobulin | 0.0451834 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0445 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0426385 |
| COG6 | component of oligomeric golgi complex 6 | 0.041392 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0412455 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0400014 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0391348 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0386818 |
| KLF6 | Kruppel-like factor 6 | 0.0382176 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0379754 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0377206 |
| GOLGA4 | golgin A4 | 0.0373724 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0367594 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0361653 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0354178 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0339281 |
| CLDN4 | claudin 4 | 0.032996 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0327796 |
| LCN2 | lipocalin 2 | 0.0320295 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0318143 |
| EHF | ets homologous factor | 0.0314298 |
| UBL3 | ubiquitin-like 3 | 0.0310327 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0302055 |
| PDZD8 | PDZ domain containing 8 | 0.0299795 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0299319 |
| XDH | xanthine dehydrogenase | 0.0296053 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0294727 |
| ERBIN | erbb2 interacting protein | 0.0292647 |
| FHL2 | four and a half LIM domains 2 | 0.0288172 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0279379 |
| SFTPA2 | surfactant protein A2 | 0.0275974 |
| SLK | STE20-like kinase | 0.026961 |
| PGK1 | phosphoglycerate kinase 1 | 0.0268676 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0266776 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0266523 |
| SEC24A | SEC24 family member A | 0.0266098 |
| COPA | coatomer protein complex, subunit alpha | 0.0265184 |
| TXNRD1 | thioredoxin reductase 1 | 0.0258473 |
| EFNB2 | ephrin-B2 | 0.0256765 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.025535 |
| RNF149 | ring finger protein 149 | 0.025364 |
| SEC24D | SEC24 family member D | 0.0252068 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0251001 |
| HKDC1 | hexokinase domain containing 1 | 0.0250098 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0245156 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0243087 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0241843 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0240406 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0239007 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0237625 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0237379 |
| TJP1 | tight junction protein 1 | 0.0235538 |
| RBM47 | RNA binding motif protein 47 | 0.0233505 |
| SPAG9 | sperm associated antigen 9 | 0.0232507 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.023009 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229714 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.022856 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0227493 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0220726 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.021777 |
| UBAP1 | ubiquitin associated protein 1 | 0.0215934 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0214862 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0213451 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0212561 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0211034 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0210719 |
| TRIM2 | tripartite motif containing 2 | 0.0210329 |
| JUN | jun proto-oncogene | 0.0207948 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0207578 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.020721 |
| KYNU | kynureninase | 0.0206734 |
| TFG | TRK-fused gene | 0.0206184 |
| RND3 | Rho family GTPase 3 | 0.0205574 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0204143 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0203929 |
| KLHL24 | kelch-like family member 24 | 0.0199934 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0199217 |
| DST | dystonin | 0.0198592 |
| PHF3 | PHD finger protein 3 | 0.0198252 |
| TMEM51 | transmembrane protein 51 | 0.0197819 |
| EREG | epiregulin | 0.0197538 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0196243 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.162301 |
| LYZ | lysozyme | -0.116891 |
| PTMA | prothymosin, alpha | -0.112156 |
| NPSR1 | neuropeptide S receptor 1 | -0.111946 |
| INTS6 | integrator complex subunit 6 | -0.110107 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.10711 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.106916 |
| SP100 | SP100 nuclear antigen | -0.106406 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.104115 |
| XAF1 | XIAP associated factor 1 | -0.0993087 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0980375 |
| PLSCR2 | phospholipid scramblase 2 | -0.0909007 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0842249 |
| RIGI | RNA sensor RIG-I | -0.0825525 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0802231 |
| PRKCA | protein kinase C, alpha | -0.0743407 |
| VCL | vinculin | -0.0722294 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0719153 |
| RNF213 | ring finger protein 213 | -0.0716318 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0667903 |
| MX1 | MX dynamin-like GTPase 1 | -0.0639979 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0613736 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0595258 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.059514 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0576437 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0527706 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0525059 |
| EPHB2 | EPH receptor B2 | -0.0510808 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0475117 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0474219 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0473342 |
| RAD51B | RAD51 paralog B | -0.0466857 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0466469 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0466209 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0453635 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0451073 |
| H1-0 | H1.0 linker histone | -0.0446846 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0444374 |
| SQSTM1 | sequestosome 1 | -0.0440898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0429037 |
| TNS4 | tensin 4 | -0.0427318 |
| CUX1 | cut-like homeobox 1 | -0.0415026 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0407209 |
| MSI2 | musashi RNA-binding protein 2 | -0.0387353 |
| AHNAK | AHNAK nucleoprotein | -0.0385092 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0383579 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0381519 |
| MX2 | MX dynamin-like GTPase 2 | -0.0373734 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0370552 |
| SSH2 | slingshot protein phosphatase 2 | -0.0370073 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0366095 |
| PLSCR1 | phospholipid scramblase 1 | -0.0364753 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0357743 |
| PMP22 | peripheral myelin protein 22 | -0.0347209 |
| PERP | PERP, TP53 apoptosis effector | -0.0346097 |
| ITGA6 | integrin, alpha 6 | -0.0345095 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0344081 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0333769 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0330156 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0322944 |
| APOL1 | apolipoprotein L, 1 | -0.0314705 |
| IER3 | immediate early response 3 | -0.0312556 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0307169 |
| FBXO39 | F-box protein 39 | -0.0307155 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0300625 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0295485 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0288219 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276639 |
| RPS24 | ribosomal protein S24 | -0.0274458 |
| DENND1A | DENN/MADD domain containing 1A | -0.0272188 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0268169 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0266724 |
| PTK2 | protein tyrosine kinase 2 | -0.026112 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0260953 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0254253 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0253387 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0250948 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0246508 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0240273 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.02379 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236832 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0236681 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0236503 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0236054 |
| TUFT1 | tuftelin 1 | -0.0233408 |
| ACTG1 | actin gamma 1 | -0.0232055 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.023183 |
| LAP3 | leucine aminopeptidase 3 | -0.0229615 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0228658 |
| APOL6 | apolipoprotein L, 6 | -0.0228444 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0226747 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0225209 |
| ARHGAP27 | Rho GTPase activating protein 27 | -0.0223791 |
| MECOM | MDS1 and EVI1 complex locus | -0.0220184 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0218711 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0218261 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0218233 |
| ASPH | aspartate beta-hydroxylase | -0.0217503 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0216451 |
| DIAPH3 | diaphanous-related formin 3 | -0.0216315 |
