| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.174217 |
| MTSS1 | metastasis suppressor 1 | 0.147812 |
| TGM2 | transglutaminase 2 | 0.111808 |
| MEF2A | myocyte enhancer factor 2A | 0.109074 |
| IGF2 | insulin-like growth factor 2 | 0.0951196 |
| STC1 | stanniocalcin 1 | 0.082374 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0770591 |
| PODXL | podocalyxin-like | 0.0748853 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0747025 |
| LAMC2 | laminin, gamma 2 | 0.0656622 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0653446 |
| CD44 | CD44 molecule (Indian blood group) | 0.0622425 |
| SLK | STE20-like kinase | 0.060818 |
| MSN | moesin | 0.0603671 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.057557 |
| B2M | beta-2-microglobulin | 0.0548195 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0539922 |
| DOK5 | docking protein 5 | 0.0536789 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0524696 |
| MT2A | metallothionein 2A | 0.050278 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0474232 |
| RAI14 | retinoic acid induced 14 | 0.0469416 |
| JMJD1C | jumonji domain containing 1C | 0.045604 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0438618 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0436903 |
| PCDH1 | protocadherin 1 | 0.0435057 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0432024 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0425474 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0413269 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0391755 |
| RPL37 | ribosomal protein L37 | 0.03811 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0380943 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.037987 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0375783 |
| LMO7 | LIM domain 7 | 0.0373041 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.036673 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0366543 |
| RPS2 | ribosomal protein S2 | 0.0361939 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0360089 |
| CALB1 | calbindin 1, 28kDa | 0.0355624 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0353012 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0347101 |
| FOSL1 | FOS-like antigen 1 | 0.0346885 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0346438 |
| PYGL | phosphorylase, glycogen, liver | 0.0344412 |
| NCOR2 | nuclear receptor corepressor 2 | 0.034306 |
| ANGPTL4 | angiopoietin-like 4 | 0.0342927 |
| ANXA1 | annexin A1 | 0.034101 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.03308 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0328744 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0324726 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0321279 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0320086 |
| RPS12 | ribosomal protein S12 | 0.0320027 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0319983 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0318821 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0317035 |
| LAMA5 | laminin, alpha 5 | 0.0315868 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.031578 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0311404 |
| SQLE | squalene epoxidase | 0.030995 |
| HLA-E | major histocompatibility complex, class I, E | 0.0308269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0304895 |
| C1D | C1D nuclear receptor corepressor | 0.0303627 |
| ARRDC3 | arrestin domain containing 3 | 0.0295085 |
| SIK3 | SIK family kinase 3 | 0.0294862 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0293035 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0290519 |
| RNF217 | ring finger protein 217 | 0.0290378 |
| MYADM | myeloid-associated differentiation marker | 0.0290082 |
| IFI44L | interferon-induced protein 44-like | 0.0285557 |
| CDCP1 | CUB domain containing protein 1 | 0.0281553 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0277551 |
| EFNA5 | ephrin-A5 | 0.0269301 |
| KIAA1217 | KIAA1217 | 0.0269286 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.026877 |
| FNIP1 | folliculin interacting protein 1 | 0.0267087 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0266339 |
| TMF1 | TATA element modulatory factor 1 | 0.0260678 |
| KLF6 | Kruppel-like factor 6 | 0.0260402 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0258537 |
| MT1E | metallothionein 1E | 0.0258493 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0256812 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0254456 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0251781 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0251431 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0249103 |
| TPM3 | tropomyosin 3 | 0.0245972 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0242731 |
| EPHA2 | EPH receptor A2 | 0.0235645 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0235337 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0232903 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0231038 |
| HAS2 | hyaluronan synthase 2 | 0.0229824 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0229113 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0228718 |
| VEGFA | vascular endothelial growth factor A | 0.0228443 |
| NFIB | nuclear factor I/B | 0.0228206 |
| TXNIP | thioredoxin interacting protein | 0.0226955 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.022281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.158247 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.144396 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.121795 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.119783 |
| PTMA | prothymosin, alpha | -0.100771 |
| KRT17 | keratin 17, type I | -0.0962961 |
| TMSB10 | thymosin beta 10 | -0.0944515 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0844986 |
| FLNB | filamin B, beta | -0.0752017 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0733237 |
| PALLD | palladin, cytoskeletal associated protein | -0.0712908 |
| RBM39 | RNA binding motif protein 39 | -0.0701032 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0683797 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0677953 |
| RPS21 | ribosomal protein S21 | -0.0641862 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0621169 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0580571 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0574058 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0571285 |
| RPS24 | ribosomal protein S24 | -0.0566797 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0565493 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0542403 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0542348 |
| ACTN4 | actinin, alpha 4 | -0.0532827 |
| VCL | vinculin | -0.0531894 |
| UBC | ubiquitin C | -0.0528713 |
| H1-0 | H1.0 linker histone | -0.0515472 |
| CANX | calnexin | -0.0504046 |
| LMNA | lamin A/C | -0.0502736 |
| ANLN | anillin, actin binding protein | -0.0502686 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.047289 |
| ENO1 | enolase 1, (alpha) | -0.0470345 |
| S100A10 | S100 calcium binding protein A10 | -0.0461952 |
| KRT14 | keratin 14, type I | -0.0434092 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0431914 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0427572 |
| CAVIN1 | caveolae associated protein 1 | -0.0425006 |
| NEK7 | NIMA-related kinase 7 | -0.0409824 |
| RPS27A | ribosomal protein S27a | -0.0407325 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0397216 |
| PLEC | plectin | -0.0388556 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0375622 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0374714 |
| AOPEP | aminopeptidase O (putative) | -0.0371817 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0364938 |
| NRCAM | neuronal cell adhesion molecule | -0.0364829 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0359971 |
| SDC4 | syndecan 4 | -0.0355302 |
| HDLBP | high density lipoprotein binding protein | -0.0351971 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0349973 |
| INTS6 | integrator complex subunit 6 | -0.0349948 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.034227 |
| KRT6A | keratin 6A, type II | -0.0341932 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0340956 |
| RIGI | RNA sensor RIG-I | -0.0338852 |
| IER3 | immediate early response 3 | -0.0336869 |
| BLCAP | bladder cancer associated protein | -0.0333189 |
| SMAD3 | SMAD family member 3 | -0.0311497 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0306117 |
| PRELID2 | PRELI domain containing 2 | -0.0305804 |
| KRT8 | keratin 8, type II | -0.0303591 |
| RRBP1 | ribosome binding protein 1 | -0.030294 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0301927 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0297173 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0296058 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0295618 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0290144 |
| ZNF217 | zinc finger protein 217 | -0.0289786 |
| NRG1 | neuregulin 1 | -0.0285672 |
| RPS25 | ribosomal protein S25 | -0.0281501 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0277785 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0276331 |
| FUS | FUS RNA binding protein | -0.0272465 |
| TMEM263 | transmembrane protein 263 | -0.0271279 |
| RPS23 | ribosomal protein S23 | -0.0270939 |
| RPL31 | ribosomal protein L31 | -0.027056 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0270377 |
| FOXO1 | forkhead box O1 | -0.0270079 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.026963 |
| CLIC4 | chloride intracellular channel 4 | -0.0266714 |
| RPS6 | ribosomal protein S6 | -0.0265208 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0263111 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0258327 |
| ANXA2 | annexin A2 | -0.0256577 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0255121 |
| RPS13 | ribosomal protein S13 | -0.0254864 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0251016 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0250241 |
| SULF1 | sulfatase 1 | -0.0249839 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0248948 |
| IRF1 | interferon regulatory factor 1 | -0.0246859 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0246594 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.024498 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0243898 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0242424 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0241768 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0240803 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0239514 |
| RPL23 | ribosomal protein L23 | -0.0239031 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0238488 |
