| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0889698 |
| FAT1 | FAT atypical cadherin 1 | 0.0852164 |
| RPS12 | ribosomal protein S12 | 0.0850218 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0740634 |
| LMO7 | LIM domain 7 | 0.0698236 |
| RPS8 | ribosomal protein S8 | 0.0636064 |
| VEGFA | vascular endothelial growth factor A | 0.0623229 |
| MYO1E | myosin IE | 0.058926 |
| ONECUT3 | one cut homeobox 3 | 0.0576342 |
| MT2A | metallothionein 2A | 0.0570108 |
| AREG | amphiregulin | 0.0531992 |
| TXNIP | thioredoxin interacting protein | 0.0524674 |
| NDRG1 | N-myc downstream regulated 1 | 0.0511635 |
| MUC13 | mucin 13, cell surface associated | 0.050987 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0494849 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0491126 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0463904 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.044545 |
| RPS2 | ribosomal protein S2 | 0.0444122 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0443257 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0439054 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.041789 |
| NEBL | nebulette | 0.040345 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0397309 |
| RPL37A | ribosomal protein L37a | 0.0396067 |
| EGFR | epidermal growth factor receptor | 0.0389553 |
| ASPH | aspartate beta-hydroxylase | 0.0389488 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0387154 |
| KLF6 | Kruppel-like factor 6 | 0.0380506 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0379152 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0373302 |
| RIGI | RNA sensor RIG-I | 0.0363516 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0350327 |
| B2M | beta-2-microglobulin | 0.0343894 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342499 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0341742 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0336743 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0334487 |
| ABHD2 | abhydrolase domain containing 2 | 0.0332893 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0331972 |
| RPL36 | ribosomal protein L36 | 0.0330182 |
| RPL18 | ribosomal protein L18 | 0.0322145 |
| RPS27 | ribosomal protein S27 | 0.0312605 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0308681 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0308482 |
| KIF5B | kinesin family member 5B | 0.0308427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303044 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0302449 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0297122 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0292136 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0290788 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.028411 |
| ATXN1 | ataxin 1 | 0.0281366 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.028096 |
| SET | SET nuclear proto-oncogene | 0.0279919 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0276506 |
| RPS3 | ribosomal protein S3 | 0.0275208 |
| PCBP2 | poly(rC) binding protein 2 | 0.0271829 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0258416 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0256883 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0255285 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0253782 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0251901 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0246032 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.024546 |
| RNF213 | ring finger protein 213 | 0.0243785 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0243531 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0243412 |
| PDZD8 | PDZ domain containing 8 | 0.0238207 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0237181 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0235506 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0234255 |
| EMP1 | epithelial membrane protein 1 | 0.0231931 |
| TMC5 | transmembrane channel-like 5 | 0.0229997 |
| TJP1 | tight junction protein 1 | 0.0228197 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0225194 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0222469 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0222158 |
| DSPP | dentin sialophosphoprotein | 0.0221358 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0220406 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0219877 |
| RORA | RAR-related orphan receptor A | 0.0217435 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.021726 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0216056 |
| CLDN4 | claudin 4 | 0.0214784 |
| SNX9 | sorting nexin 9 | 0.0214172 |
| MYO5B | myosin VB | 0.0212982 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0211238 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0211229 |
| SIK3 | SIK family kinase 3 | 0.0211054 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0206732 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0206024 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0205819 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0204913 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0204896 |
| JUN | jun proto-oncogene | 0.0202008 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.020189 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0201085 |
| SMYD3 | SET and MYND domain containing 3 | 0.0199963 |
| EZR | ezrin | 0.0198908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.2582 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.22324 |
| NPSR1 | neuropeptide S receptor 1 | -0.163415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153062 |
| TMSB10 | thymosin beta 10 | -0.149091 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.104828 |
| KRT18 | keratin 18, type I | -0.0603329 |
| ACTN4 | actinin, alpha 4 | -0.05539 |
| AHNAK | AHNAK nucleoprotein | -0.0541188 |
| RPS24 | ribosomal protein S24 | -0.0531976 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0498691 |
| PIGR | polymeric immunoglobulin receptor | -0.0490363 |
| RBM39 | RNA binding motif protein 39 | -0.0478597 |
| VCL | vinculin | -0.043044 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0407116 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0404196 |
| RRBP1 | ribosome binding protein 1 | -0.0395903 |
| GPHN | gephyrin | -0.0395194 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0389614 |
| RNF43 | ring finger protein 43 | -0.0387588 |
| RPS21 | ribosomal protein S21 | -0.0370129 |
| HDLBP | high density lipoprotein binding protein | -0.0365278 |
| TFRC | transferrin receptor | -0.0364603 |
| OGA | O-GlcNAcase | -0.0356894 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355574 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0346132 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0339784 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0336258 |
| TRIM2 | tripartite motif containing 2 | -0.0336092 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0333721 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0330545 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0325173 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0319819 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.031854 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0316445 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0316076 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0314407 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0310463 |
| PRSS3 | protease, serine, 3 | -0.0309216 |
| KRT8 | keratin 8, type II | -0.0308222 |
| NRN1 | neuritin 1 | -0.0304889 |
| RAB10 | RAB10, member RAS oncogene family | -0.0303669 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0292208 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.029172 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0288727 |
| MED13L | mediator complex subunit 13-like | -0.0287443 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0281681 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0281312 |
| PCDHB16 | protocadherin beta 16 | -0.0281013 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0277422 |
| ANXA2 | annexin A2 | -0.0276373 |
| AGR2 | anterior gradient 2 | -0.0274841 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.027238 |
| GDF15 | growth differentiation factor 15 | -0.026886 |
| RPL32 | ribosomal protein L32 | -0.0267587 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0266501 |
| ABLIM1 | actin binding LIM protein 1 | -0.026323 |
| IER3 | immediate early response 3 | -0.0259696 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0255475 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0254368 |
| HMGB1 | high mobility group box 1 | -0.0253218 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0251477 |
| SERINC5 | serine incorporator 5 | -0.0249421 |
| CLTC | clathrin, heavy chain (Hc) | -0.024931 |
| H3-3B | H3.3 histone B | -0.024615 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0245038 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0243963 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0243763 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.024364 |
| SETD5 | SET domain containing 5 | -0.0240637 |
| LDHA | lactate dehydrogenase A | -0.024029 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0239094 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0237637 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0236742 |
| NFIA | nuclear factor I/A | -0.0230433 |
| H1-0 | H1.0 linker histone | -0.0229867 |
| BCL2L1 | BCL2-like 1 | -0.0229049 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0228348 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0228291 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0227985 |
| DEK | DEK proto-oncogene | -0.0227768 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0227595 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0227439 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0226135 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0225567 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0224956 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0224828 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0221447 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0219716 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0219625 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0219198 |
| S100A10 | S100 calcium binding protein A10 | -0.0218217 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0215839 |
| POTEF | POTE ankyrin domain family, member F | -0.0215793 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0215385 |
| ETNK1 | ethanolamine kinase 1 | -0.0215122 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0214402 |
| MSI2 | musashi RNA-binding protein 2 | -0.0212647 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.021231 |
| INSIG1 | insulin induced gene 1 | -0.0211577 |
