| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.142481 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.123563 |
| MT2A | metallothionein 2A | 0.118638 |
| DST | dystonin | 0.0873313 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0825901 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0819101 |
| EREG | epiregulin | 0.0808597 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0787286 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0774482 |
| MT1X | metallothionein 1X | 0.0726068 |
| MT1E | metallothionein 1E | 0.0722302 |
| KLF6 | Kruppel-like factor 6 | 0.0717113 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0677812 |
| PDE10A | phosphodiesterase 10A | 0.0651599 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0650122 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0648469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.062157 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0605348 |
| CAPRIN2 | caprin family member 2 | 0.0586385 |
| RUNX1 | runt-related transcription factor 1 | 0.055313 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0546786 |
| RPS12 | ribosomal protein S12 | 0.0525373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0521571 |
| ANGPTL4 | angiopoietin-like 4 | 0.0508962 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0501438 |
| CD44 | CD44 molecule (Indian blood group) | 0.0496001 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0494977 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0494697 |
| PYGL | phosphorylase, glycogen, liver | 0.0486587 |
| RACK1 | receptor for activated C kinase 1 | 0.0484401 |
| PGK1 | phosphoglycerate kinase 1 | 0.0481473 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0480887 |
| HMGA1 | high mobility group AT-hook 1 | 0.0468126 |
| TMSB4X | thymosin beta 4, X-linked | 0.0465952 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0459178 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0457963 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0456838 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0455414 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0446147 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0436739 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0418402 |
| RPS2 | ribosomal protein S2 | 0.0418393 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0409502 |
| JUN | jun proto-oncogene | 0.0391857 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0382195 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.038145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.037707 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0370389 |
| RTN4 | reticulon 4 | 0.0359008 |
| EMP1 | epithelial membrane protein 1 | 0.035758 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357475 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0353101 |
| EZR | ezrin | 0.0352352 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0343186 |
| RIGI | RNA sensor RIG-I | 0.0342786 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0340886 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.034016 |
| FMNL2 | formin-like 2 | 0.0332705 |
| TMEM41B | transmembrane protein 41B | 0.0327639 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0325912 |
| ZNF292 | zinc finger protein 292 | 0.0319727 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.03172 |
| FOSL1 | FOS-like antigen 1 | 0.0314397 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0314257 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0311877 |
| AREG | amphiregulin | 0.0310895 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0310101 |
| SPAG9 | sperm associated antigen 9 | 0.0309633 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0308089 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0307703 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.030211 |
| F2R | coagulation factor II (thrombin) receptor | 0.0298113 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.029699 |
| YBX3 | Y box binding protein 3 | 0.0296198 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0288835 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0287908 |
| S100A6 | S100 calcium binding protein A6 | 0.0287812 |
| MEF2A | myocyte enhancer factor 2A | 0.0287481 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0283699 |
| RPL26 | ribosomal protein L26 | 0.0283568 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283135 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0281785 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0280743 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0279282 |
| ARRDC3 | arrestin domain containing 3 | 0.0271774 |
| RPL12 | ribosomal protein L12 | 0.02659 |
| SET | SET nuclear proto-oncogene | 0.0262646 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0258544 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0258285 |
| APP | amyloid beta (A4) precursor protein | 0.0256184 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0254243 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0253759 |
| RAI1 | retinoic acid induced 1 | 0.0250523 |
| TXNRD1 | thioredoxin reductase 1 | 0.0245959 |
| PRKCE | protein kinase C, epsilon | 0.0245808 |
| RPS8 | ribosomal protein S8 | 0.0245384 |
| TP63 | tumor protein p63 | 0.0242829 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0242313 |
| VCL | vinculin | 0.0241125 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0240773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.181814 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0855147 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0659332 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0605925 |
| TMSB10 | thymosin beta 10 | -0.0488432 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0483208 |
| CENPF | centromere protein F, 350/400kDa | -0.0471179 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0469104 |
| RPS24 | ribosomal protein S24 | -0.0434382 |
| POTEF | POTE ankyrin domain family, member F | -0.0382961 |
| RPS23 | ribosomal protein S23 | -0.0379151 |
| RPS6 | ribosomal protein S6 | -0.0346019 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339026 |
| CANX | calnexin | -0.0319766 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0309925 |
| RPL35A | ribosomal protein L35a | -0.0297317 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0295877 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284646 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0282543 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0255515 |
| MAP4 | microtubule-associated protein 4 | -0.0245372 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0244539 |
| RPL7A | ribosomal protein L7a | -0.0236575 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0235696 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0235446 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0227922 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0226431 |
| COL5A2 | collagen, type V, alpha 2 | -0.0225077 |
| RPS25 | ribosomal protein S25 | -0.0224439 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.022105 |
| INTS6 | integrator complex subunit 6 | -0.0218838 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0214958 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0213882 |
| RPL19 | ribosomal protein L19 | -0.020898 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0204946 |
| TP53 | tumor protein p53 | -0.0202371 |
| COPA | coatomer protein complex, subunit alpha | -0.0199427 |
| AHNAK | AHNAK nucleoprotein | -0.0198077 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0196328 |
| SRGN | serglycin | -0.0195523 |
| RPS10 | ribosomal protein S10 | -0.019439 |
| EGFR | epidermal growth factor receptor | -0.0193286 |
| TPI1 | triosephosphate isomerase 1 | -0.0188731 |
| WASF2 | WAS protein family, member 2 | -0.0185472 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.018436 |
| SETX | senataxin | -0.018436 |
| RPS15 | ribosomal protein S15 | -0.0180533 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0179152 |
| RPL31 | ribosomal protein L31 | -0.0176484 |
| CAVIN1 | caveolae associated protein 1 | -0.0174599 |
| GLG1 | golgi glycoprotein 1 | -0.0173733 |
| RPS11 | ribosomal protein S11 | -0.0172548 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0169668 |
| FNIP1 | folliculin interacting protein 1 | -0.016937 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0168303 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0167908 |
| SYT1 | synaptotagmin I | -0.0166575 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0165341 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0164009 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0163642 |
| CDK12 | cyclin-dependent kinase 12 | -0.0160428 |
| BPTF | bromodomain PHD finger transcription factor | -0.0160187 |
| EFNA5 | ephrin-A5 | -0.0159884 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0157591 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0157422 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0156409 |
| HDLBP | high density lipoprotein binding protein | -0.0155361 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0155151 |
| ITGB4 | integrin, beta 4 | -0.0154491 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0153824 |
| HSPB1 | heat shock 27kDa protein 1 | -0.01528 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0151687 |
| RPL38 | ribosomal protein L38 | -0.0151477 |
| EXOC4 | exocyst complex component 4 | -0.0150736 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0150666 |
| TPX2 | TPX2, microtubule-associated | -0.0149536 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0149399 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0147684 |
| EHBP1 | EH domain binding protein 1 | -0.0147321 |
| TBCA | tubulin folding cofactor A | -0.0146865 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0145138 |
| FTL | ferritin, light polypeptide | -0.0143232 |
| CENPE | centromere protein E, 312kDa | -0.0142636 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0142534 |
| RPS13 | ribosomal protein S13 | -0.0141758 |
| MYO10 | myosin X | -0.0141066 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0139792 |
| FRYL | FRY-like | -0.0138846 |
| S100A9 | S100 calcium binding protein A9 | -0.0138584 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0137964 |
| WDR59 | WD repeat domain 59 | -0.0137163 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0135987 |
| CD109 | CD109 molecule | -0.0135454 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0133954 |
| EPHA4 | EPH receptor A4 | -0.0133452 |
| CALR | calreticulin | -0.0132604 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0132148 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0131637 |
| SHISA5 | shisa family member 5 | -0.0131408 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.01314 |
