| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.178249 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.152079 |
| TXNRD1 | thioredoxin reductase 1 | 0.118876 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.114386 |
| PM20D1 | peptidase M20 domain containing 1 | 0.102579 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0815834 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0809989 |
| FTL | ferritin, light polypeptide | 0.0784632 |
| RPS12 | ribosomal protein S12 | 0.0670959 |
| FGB | fibrinogen beta chain | 0.0669783 |
| KIF5B | kinesin family member 5B | 0.0627015 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0550796 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0531214 |
| RTN4 | reticulon 4 | 0.0523521 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0494122 |
| MT2A | metallothionein 2A | 0.0478442 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0464523 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0447472 |
| IGF2 | insulin-like growth factor 2 | 0.0443509 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0443381 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0414743 |
| ZNF292 | zinc finger protein 292 | 0.0401149 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0398955 |
| TPD52 | tumor protein D52 | 0.038761 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0385327 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0378096 |
| MATR3 | matrin 3 | 0.036832 |
| STC1 | stanniocalcin 1 | 0.0368232 |
| RPS2 | ribosomal protein S2 | 0.0365446 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0357341 |
| KLF6 | Kruppel-like factor 6 | 0.0357013 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0352771 |
| PFN1 | profilin 1 | 0.0348564 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0345737 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345143 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0345004 |
| FGG | fibrinogen gamma chain | 0.0343558 |
| USP3 | ubiquitin specific peptidase 3 | 0.0340994 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0340855 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0339697 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0338905 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0337442 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.032684 |
| RPLP1 | ribosomal protein, large, P1 | 0.0326823 |
| NCKAP1 | NCK-associated protein 1 | 0.0325676 |
| SPAG9 | sperm associated antigen 9 | 0.0322493 |
| RPL23 | ribosomal protein L23 | 0.0317009 |
| RPL18 | ribosomal protein L18 | 0.0315268 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0312502 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0303416 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0300049 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.029714 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0293863 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0287007 |
| YBX1 | Y box binding protein 1 | 0.0286764 |
| NUP58 | nucleoporin 58 | 0.0282987 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278942 |
| PFDN2 | prefoldin subunit 2 | 0.0278583 |
| YBX3 | Y box binding protein 3 | 0.0275184 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0275042 |
| PCBP2 | poly(rC) binding protein 2 | 0.027493 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0274749 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272357 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0271136 |
| WWOX | WW domain containing oxidoreductase | 0.0270811 |
| SFTPA2 | surfactant protein A2 | 0.0267667 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0262959 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0261849 |
| WDR43 | WD repeat domain 43 | 0.0260821 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0260751 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0260569 |
| TPM3 | tropomyosin 3 | 0.0259733 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0259637 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0258866 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0258797 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0254456 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0252428 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0247679 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0236237 |
| FADS2 | fatty acid desaturase 2 | 0.0235971 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.023425 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0233247 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0228423 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0226668 |
| RACK1 | receptor for activated C kinase 1 | 0.0225239 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0223554 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0222716 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0219051 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0217907 |
| B2M | beta-2-microglobulin | 0.0217593 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0216124 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0215613 |
| PCBP1 | poly(rC) binding protein 1 | 0.0213742 |
| ANXA1 | annexin A1 | 0.0211494 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0208784 |
| NEK7 | NIMA-related kinase 7 | 0.0208655 |
| JAK1 | Janus kinase 1 | 0.0207932 |
| OLA1 | Obg-like ATPase 1 | 0.0207734 |
| TNPO1 | transportin 1 | 0.0207064 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0206849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.286612 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.224788 |
| ACTG1 | actin gamma 1 | -0.134387 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0974743 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0919601 |
| IER3 | immediate early response 3 | -0.0848645 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0847918 |
| CMIP | c-Maf inducing protein | -0.0729013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0705765 |
| PTMA | prothymosin, alpha | -0.0695617 |
| TPM4 | tropomyosin 4 | -0.0692673 |
| AHNAK | AHNAK nucleoprotein | -0.0686195 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0635417 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.062162 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.059241 |
| MCL1 | myeloid cell leukemia 1 | -0.055772 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0533509 |
| VCL | vinculin | -0.0531586 |
| S100A10 | S100 calcium binding protein A10 | -0.0519989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0499799 |
| POTEF | POTE ankyrin domain family, member F | -0.0467913 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.043766 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0433049 |
| CAVIN1 | caveolae associated protein 1 | -0.0431131 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0426287 |
| TPM1 | tropomyosin 1 (alpha) | -0.041059 |
| RPS29 | ribosomal protein S29 | -0.0405731 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0398577 |
| RPS15 | ribosomal protein S15 | -0.0396372 |
| PYGL | phosphorylase, glycogen, liver | -0.0393296 |
| RPS25 | ribosomal protein S25 | -0.0389591 |
| EGR1 | early growth response 1 | -0.0385923 |
| HLA-B | major histocompatibility complex, class I, B | -0.0381234 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0379832 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0370303 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0351612 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0332661 |
| LDHA | lactate dehydrogenase A | -0.0326645 |
| RPS23 | ribosomal protein S23 | -0.0322912 |
| ATG7 | autophagy related 7 | -0.0321483 |
| EGFR | epidermal growth factor receptor | -0.0320071 |
| EXT1 | exostosin glycosyltransferase 1 | -0.031867 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0317137 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0313431 |
| DOCK4 | dedicator of cytokinesis 4 | -0.030568 |
| CUX1 | cut-like homeobox 1 | -0.0302329 |
| INTS6 | integrator complex subunit 6 | -0.0298283 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0297413 |
| PCNX4 | pecanex 4 | -0.0295085 |
| RPS24 | ribosomal protein S24 | -0.0290516 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0287768 |
| MYO1E | myosin IE | -0.0285872 |
| CDK12 | cyclin-dependent kinase 12 | -0.0282862 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0273779 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0269619 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0266119 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0265327 |
| RPS21 | ribosomal protein S21 | -0.0262945 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0261644 |
| AK1 | adenylate kinase 1 | -0.0258603 |
| UBC | ubiquitin C | -0.0257966 |
| FUS | FUS RNA binding protein | -0.0251856 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0251543 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0248917 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0247313 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0245442 |
| RHOA | ras homolog family member A | -0.0244783 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0242982 |
| RPS6 | ribosomal protein S6 | -0.0242901 |
| CALD1 | caldesmon 1 | -0.0242473 |
| RPS10 | ribosomal protein S10 | -0.0240566 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0240541 |
| NLK | nemo-like kinase | -0.0240302 |
| TNS3 | tensin 3 | -0.0240117 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0239076 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0235164 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0233762 |
| NUMB | numb homolog (Drosophila) | -0.0231498 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0228993 |
| RPS13 | ribosomal protein S13 | -0.0226213 |
| RAD51B | RAD51 paralog B | -0.0225943 |
| DOCK5 | dedicator of cytokinesis 5 | -0.022579 |
| SNX14 | sorting nexin 14 | -0.0225246 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0225243 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0224933 |
| RPL38 | ribosomal protein L38 | -0.0224584 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0224205 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0223725 |
| COPA | coatomer protein complex, subunit alpha | -0.0223703 |
| CFDP1 | craniofacial development protein 1 | -0.0223047 |
| NF1 | neurofibromin 1 | -0.0221226 |
| FLNB | filamin B, beta | -0.0219833 |
| USP34 | ubiquitin specific peptidase 34 | -0.0217252 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0214151 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0213597 |
| SBF2 | SET binding factor 2 | -0.0213483 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0213018 |
| RAN | RAN, member RAS oncogene family | -0.0213007 |
| RPL9 | ribosomal protein L9 | -0.0212815 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0211982 |
