| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.114014 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0948495 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0869485 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.073444 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0709305 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0623883 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0608991 |
| MYO1E | myosin IE | 0.05957 |
| HMGA2 | high mobility group AT-hook 2 | 0.0587172 |
| ATXN1 | ataxin 1 | 0.0561798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0540215 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0536212 |
| PKM | pyruvate kinase, muscle | 0.0529118 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0521391 |
| FMNL2 | formin-like 2 | 0.0518133 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0489524 |
| LDHA | lactate dehydrogenase A | 0.0477726 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0464473 |
| RUNX1 | runt-related transcription factor 1 | 0.0454139 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0441689 |
| VIM | vimentin | 0.0434392 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0431787 |
| NDRG1 | N-myc downstream regulated 1 | 0.0422647 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0417697 |
| STC1 | stanniocalcin 1 | 0.0416499 |
| EGFR | epidermal growth factor receptor | 0.0415263 |
| FTL | ferritin, light polypeptide | 0.0411835 |
| LAMA4 | laminin, alpha 4 | 0.0408695 |
| NAV2 | neuron navigator 2 | 0.0400487 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0400399 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0396886 |
| RPLP1 | ribosomal protein, large, P1 | 0.0392002 |
| RPS12 | ribosomal protein S12 | 0.0391472 |
| GPHN | gephyrin | 0.0390591 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0390403 |
| SYT1 | synaptotagmin I | 0.038433 |
| VCL | vinculin | 0.0383759 |
| CD44 | CD44 molecule (Indian blood group) | 0.0382668 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0373103 |
| INHBA | inhibin, beta A | 0.0371098 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0369648 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0369167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360982 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0356143 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0355871 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0355266 |
| KIF5B | kinesin family member 5B | 0.0353052 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0352279 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0345774 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0344181 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0343555 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0342997 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0339472 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0334834 |
| RPS8 | ribosomal protein S8 | 0.0330591 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0330168 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0329109 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0321918 |
| NRG1 | neuregulin 1 | 0.0320202 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0317361 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0315649 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0314397 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0314168 |
| JUN | jun proto-oncogene | 0.0313349 |
| PHF21A | PHD finger protein 21A | 0.031317 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0312905 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0312035 |
| SMYD3 | SET and MYND domain containing 3 | 0.0303082 |
| RPS27A | ribosomal protein S27a | 0.0303031 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0302146 |
| SMAD4 | SMAD family member 4 | 0.0296758 |
| RND3 | Rho family GTPase 3 | 0.0296051 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0296 |
| GPC6 | glypican 6 | 0.029595 |
| RPL26 | ribosomal protein L26 | 0.0295556 |
| OXR1 | oxidation resistance 1 | 0.0295544 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0290583 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0290241 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0289064 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0288297 |
| OSMR | oncostatin M receptor | 0.0287272 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0286014 |
| YTHDC1 | YTH domain containing 1 | 0.0285795 |
| RPLP0 | ribosomal protein, large, P0 | 0.0285493 |
| HDAC9 | histone deacetylase 9 | 0.0278769 |
| GOLGA4 | golgin A4 | 0.0278143 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0274638 |
| RBM15 | RNA binding motif protein 15 | 0.0274237 |
| ADM | adrenomedullin | 0.0271217 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0268436 |
| TMF1 | TATA element modulatory factor 1 | 0.0266889 |
| TXNIP | thioredoxin interacting protein | 0.0265339 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0263058 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0261759 |
| TJP1 | tight junction protein 1 | 0.0260574 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.025976 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0259737 |
| SRP54 | signal recognition particle 54kDa | 0.0259315 |
| PRELID2 | PRELI domain containing 2 | 0.0258004 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0257779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.158402 |
| GRB10 | growth factor receptor-bound protein 10 | -0.136056 |
| ATOSA | atos homolog A | -0.132364 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.100537 |
| MUC16 | mucin 16, cell surface associated | -0.0855269 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0820899 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0779156 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0652023 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0591088 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0574414 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0573988 |
| KIF13B | kinesin family member 13B | -0.0562107 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0553008 |
| DENND1A | DENN/MADD domain containing 1A | -0.055246 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0513879 |
| ANKRD36C | ankyrin repeat domain 36C | -0.05124 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.051054 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0510138 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0504331 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0491267 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0479929 |
| ZNF638 | zinc finger protein 638 | -0.0478107 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0453974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0448893 |
| SCEL | sciellin | -0.0444205 |
| TXNRD1 | thioredoxin reductase 1 | -0.0441068 |
| AHNAK | AHNAK nucleoprotein | -0.043587 |
| DUSP5 | dual specificity phosphatase 5 | -0.0422427 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0417295 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0417096 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0414486 |
| CMIP | c-Maf inducing protein | -0.040588 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.040276 |
| WASF2 | WAS protein family, member 2 | -0.03929 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0382357 |
| TJP2 | tight junction protein 2 | -0.0381961 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0377491 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0377392 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0373073 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0367542 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0366656 |
| ABHD17C | abhydrolase domain containing 17C | -0.036359 |
| TGFA | transforming growth factor, alpha | -0.0360572 |
| SLMAP | sarcolemma associated protein | -0.0356598 |
| ATXN2 | ataxin 2 | -0.0353727 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0352985 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0348433 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0347405 |
| RIOK3 | RIO kinase 3 | -0.034655 |
| SNX9 | sorting nexin 9 | -0.0345078 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343257 |
| PMM2 | phosphomannomutase 2 | -0.0342377 |
| NEBL | nebulette | -0.0337909 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0335206 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0334304 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.033032 |
| RBM47 | RNA binding motif protein 47 | -0.032724 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0327058 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0325969 |
| CYTH1 | cytohesin 1 | -0.0324889 |
| FAM107B | family with sequence similarity 107, member B | -0.0323109 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0322398 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0321292 |
| CLDN7 | claudin 7 | -0.0320536 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0320294 |
| MYOF | myoferlin | -0.0318824 |
| SMAD3 | SMAD family member 3 | -0.0314828 |
| LAMC2 | laminin, gamma 2 | -0.0314814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0314156 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0312998 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0305515 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.030449 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0303938 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0302127 |
| CD2AP | CD2-associated protein | -0.0301276 |
| TMEM41B | transmembrane protein 41B | -0.0300607 |
| MYO6 | myosin VI | -0.0300518 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0299629 |
| ITGB4 | integrin, beta 4 | -0.0298803 |
| TC2N | tandem C2 domains, nuclear | -0.0298421 |
| SMAD2 | SMAD family member 2 | -0.0296144 |
| MCU | mitochondrial calcium uniporter | -0.0295515 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0295199 |
| CSTB | cystatin B (stefin B) | -0.0291024 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.029031 |
| POTEF | POTE ankyrin domain family, member F | -0.0288064 |
| SETD5 | SET domain containing 5 | -0.0287721 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0284443 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0284359 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0283743 |
| CDYL | chromodomain protein, Y-like | -0.0280119 |
| FOXO3 | forkhead box O3 | -0.0276398 |
| SQSTM1 | sequestosome 1 | -0.0275263 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0273794 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0273133 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0272735 |
| PHF14 | PHD finger protein 14 | -0.0270511 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0269871 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0265794 |
| MEF2A | myocyte enhancer factor 2A | -0.0263815 |
