| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Terfenadine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.204598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.191005 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.172617 |
| FTL | ferritin, light polypeptide | 0.103486 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0931395 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0924401 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0918354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0900766 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0851324 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0850434 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0793012 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0728335 |
| RPS12 | ribosomal protein S12 | 0.0694996 |
| LAMB3 | laminin, beta 3 | 0.0665857 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0641251 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0637787 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0632831 |
| HMGA1 | high mobility group AT-hook 1 | 0.06281 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0611441 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0610648 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0598271 |
| RACK1 | receptor for activated C kinase 1 | 0.0587702 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0581245 |
| FN1 | fibronectin 1 | 0.0572514 |
| FAM13A | family with sequence similarity 13, member A | 0.0531429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0509739 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0501737 |
| ARRDC3 | arrestin domain containing 3 | 0.0490905 |
| RPS3 | ribosomal protein S3 | 0.0489208 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0475857 |
| PRRC2C | proline-rich coiled-coil 2C | 0.047524 |
| RPLP1 | ribosomal protein, large, P1 | 0.0467878 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0455085 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0443133 |
| RPL23 | ribosomal protein L23 | 0.0427574 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0413776 |
| RYBP | RING1 and YY1 binding protein | 0.0409233 |
| PCBP2 | poly(rC) binding protein 2 | 0.0401575 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0398015 |
| USP53 | ubiquitin specific peptidase 53 | 0.0395906 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0380131 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0376979 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0366633 |
| SPAG9 | sperm associated antigen 9 | 0.0364283 |
| RPS17 | ribosomal protein S17 | 0.0361985 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.035675 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0356367 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0353565 |
| CALR | calreticulin | 0.0352701 |
| RPS19 | ribosomal protein S19 | 0.0348898 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0345289 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0341534 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0340119 |
| RPS2 | ribosomal protein S2 | 0.0339806 |
| RPL12 | ribosomal protein L12 | 0.0334758 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0331303 |
| TMF1 | TATA element modulatory factor 1 | 0.0328733 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0327303 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0322684 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0321883 |
| MSN | moesin | 0.0321096 |
| RPL35A | ribosomal protein L35a | 0.0320864 |
| MT2A | metallothionein 2A | 0.0319134 |
| RBM25 | RNA binding motif protein 25 | 0.0315576 |
| RPL37 | ribosomal protein L37 | 0.0313624 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0313025 |
| DUSP10 | dual specificity phosphatase 10 | 0.0306047 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0305921 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0304464 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0303379 |
| RPS27 | ribosomal protein S27 | 0.0302276 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0300509 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0300262 |
| RNF145 | ring finger protein 145 | 0.029717 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0296614 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0295396 |
| GOLGA4 | golgin A4 | 0.0293864 |
| TPD52 | tumor protein D52 | 0.0291682 |
| DTNA | dystrobrevin, alpha | 0.0290868 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0287826 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0286431 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283606 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0278129 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0277505 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0275502 |
| BRD2 | bromodomain containing 2 | 0.0274187 |
| JAK1 | Janus kinase 1 | 0.0273554 |
| HMGB2 | high mobility group box 2 | 0.0272924 |
| S100A6 | S100 calcium binding protein A6 | 0.0272228 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0271641 |
| SGMS2 | sphingomyelin synthase 2 | 0.0271038 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0270998 |
| UPP1 | uridine phosphorylase 1 | 0.0269737 |
| ZNF292 | zinc finger protein 292 | 0.0269215 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0268651 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0267596 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0266696 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0266414 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0265166 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0263879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0889567 |
| AHNAK | AHNAK nucleoprotein | -0.072563 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0724397 |
| ASPH | aspartate beta-hydroxylase | -0.058107 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0523475 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0503334 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0478328 |
| CCND1 | cyclin D1 | -0.0391865 |
| CD2AP | CD2-associated protein | -0.0371904 |
| LMO7 | LIM domain 7 | -0.0361058 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0358655 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0342918 |
| VCL | vinculin | -0.0326784 |
| TPM4 | tropomyosin 4 | -0.0317826 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0306321 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293069 |
| H1-0 | H1.0 linker histone | -0.0289412 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0285379 |
| RHOA | ras homolog family member A | -0.0282997 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0269251 |
| RRBP1 | ribosome binding protein 1 | -0.0267743 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0266161 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0238665 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0227186 |
| CUX1 | cut-like homeobox 1 | -0.0227047 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0225512 |
| COL1A1 | collagen, type I, alpha 1 | -0.0221615 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0221034 |
| OGA | O-GlcNAcase | -0.0217414 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.021116 |
| KRT18 | keratin 18, type I | -0.0204378 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0201853 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0201235 |
| FBXO34 | F-box protein 34 | -0.0200212 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.019705 |
| CAB39 | calcium binding protein 39 | -0.01962 |
| PLAU | plasminogen activator, urokinase | -0.0193606 |
| RAI14 | retinoic acid induced 14 | -0.0190694 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0188702 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.018655 |
| TMEM263 | transmembrane protein 263 | -0.01854 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0184019 |
| KRT7 | keratin 7, type II | -0.0183963 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0183693 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0182785 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0181067 |
| SEC24D | SEC24 family member D | -0.0180508 |
| S100A10 | S100 calcium binding protein A10 | -0.0179169 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0175157 |
| FRMD5 | FERM domain containing 5 | -0.017512 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0173232 |
| H3-3B | H3.3 histone B | -0.0172927 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0170714 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0169313 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0167619 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0166641 |
| ZNF217 | zinc finger protein 217 | -0.0166303 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0165223 |
| KRT8 | keratin 8, type II | -0.0163183 |
| MAP4 | microtubule-associated protein 4 | -0.01631 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0154473 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.015325 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0150568 |
| MCU | mitochondrial calcium uniporter | -0.014983 |
| HMGA2 | high mobility group AT-hook 2 | -0.0149277 |
| RPS15 | ribosomal protein S15 | -0.014916 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0149124 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0149089 |
| CAVIN1 | caveolae associated protein 1 | -0.0148107 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0147315 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0146333 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0145882 |
| SQSTM1 | sequestosome 1 | -0.0145655 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0144716 |
| TTLL11 | tubulin tyrosine ligase-like family member 11 | -0.0143035 |
| CD47 | CD47 molecule | -0.0142945 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0142393 |
| HLA-B | major histocompatibility complex, class I, B | -0.0141403 |
| RASAL2 | RAS protein activator like 2 | -0.0141128 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0136827 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0136163 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0135227 |
| IER3 | immediate early response 3 | -0.0130875 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0130063 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0129738 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0129573 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0128376 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0127996 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0125938 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0124007 |
| EXOC4 | exocyst complex component 4 | -0.012293 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0121974 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.012187 |
| BCL2L1 | BCL2-like 1 | -0.0120658 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.01184 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0117718 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0115907 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0115127 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0113105 |
| MSI2 | musashi RNA-binding protein 2 | -0.0112 |
