| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.16249 |
| ANK2 | ankyrin 2, neuronal | 0.0870069 |
| DST | dystonin | 0.0808911 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0801543 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0795394 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0753353 |
| RPS12 | ribosomal protein S12 | 0.0750993 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0740747 |
| SRP54 | signal recognition particle 54kDa | 0.0619682 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.061622 |
| ITGAV | integrin, alpha V | 0.0615314 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0561865 |
| PRTG | protogenin | 0.0547442 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0531789 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0531412 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0509907 |
| PFN1 | profilin 1 | 0.0504505 |
| RPS2 | ribosomal protein S2 | 0.0469922 |
| PEG10 | paternally expressed 10 | 0.0445589 |
| RPS3 | ribosomal protein S3 | 0.0440265 |
| PHIP | pleckstrin homology domain interacting protein | 0.0418823 |
| NCKAP1 | NCK-associated protein 1 | 0.0413278 |
| HDAC9 | histone deacetylase 9 | 0.0400871 |
| RPS8 | ribosomal protein S8 | 0.0390464 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0388784 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0388436 |
| FOXP2 | forkhead box P2 | 0.0386231 |
| RPS6 | ribosomal protein S6 | 0.0379148 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0372027 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0371873 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0365543 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0362243 |
| CALR | calreticulin | 0.0361559 |
| SET | SET nuclear proto-oncogene | 0.0359442 |
| RTN4 | reticulon 4 | 0.0357414 |
| CENPF | centromere protein F, 350/400kDa | 0.0350647 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0350627 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0347096 |
| ENAH | enabled homolog (Drosophila) | 0.034265 |
| RREB1 | ras responsive element binding protein 1 | 0.0341261 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341009 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0338287 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0337134 |
| TJP1 | tight junction protein 1 | 0.0336356 |
| PCBP2 | poly(rC) binding protein 2 | 0.033525 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0329687 |
| KIF5B | kinesin family member 5B | 0.0322696 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0320958 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0311999 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0310919 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0306867 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0305549 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0297474 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0296901 |
| SNX6 | sorting nexin 6 | 0.0296575 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0296008 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0294986 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0289654 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0286792 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.02852 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0284198 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0282987 |
| JMJD1C | jumonji domain containing 1C | 0.0281748 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0277831 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275486 |
| NFIA | nuclear factor I/A | 0.0275192 |
| SBF2 | SET binding factor 2 | 0.0275052 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0271885 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0270515 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0269256 |
| NHSL1 | NHS-like 1 | 0.0269162 |
| THOC2 | THO complex 2 | 0.0268662 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.026596 |
| CFL2 | cofilin 2 (muscle) | 0.0265216 |
| RASAL2 | RAS protein activator like 2 | 0.0264707 |
| RPL36 | ribosomal protein L36 | 0.0261153 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0260255 |
| EVI5 | ecotropic viral integration site 5 | 0.0256961 |
| FIGN | fidgetin | 0.0256892 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0253828 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0252303 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0251519 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0250174 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0249685 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0249172 |
| MYO10 | myosin X | 0.0248962 |
| STK38 | serine/threonine kinase 38 | 0.0248962 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0248688 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0247538 |
| RBM20 | RNA binding motif protein 20 | 0.0245887 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0245572 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0244663 |
| RBM25 | RNA binding motif protein 25 | 0.0242945 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0242651 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0242551 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0240946 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0240739 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.023948 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0239162 |
| HMGA2 | high mobility group AT-hook 2 | 0.0238727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL3A1 | collagen, type III, alpha 1 | -0.0998233 |
| PTMA | prothymosin, alpha | -0.0836425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0707987 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0590516 |
| COL1A2 | collagen, type I, alpha 2 | -0.0539191 |
| TMSB10 | thymosin beta 10 | -0.0511969 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0477873 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0473953 |
| H1-0 | H1.0 linker histone | -0.0435906 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0419824 |
| PCDH9 | protocadherin 9 | -0.0419157 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0407668 |
| SFRP4 | secreted frizzled-related protein 4 | -0.039201 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0370976 |
| SPAG9 | sperm associated antigen 9 | -0.0367592 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0362142 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0342992 |
| RPS16 | ribosomal protein S16 | -0.0340529 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0334941 |
| GPC3 | glypican 3 | -0.0331245 |
| MED12L | mediator complex subunit 12-like | -0.0296377 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0291055 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0285573 |
| EMP1 | epithelial membrane protein 1 | -0.0282991 |
| ACTG1 | actin gamma 1 | -0.0281284 |
| VIM | vimentin | -0.0274239 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.027372 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0273087 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0270785 |
| CAVIN1 | caveolae associated protein 1 | -0.0264136 |
| RIGI | RNA sensor RIG-I | -0.026252 |
| VCL | vinculin | -0.0262132 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0257963 |
| APOE | apolipoprotein E | -0.0257494 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0252213 |
| HMCN1 | hemicentin 1 | -0.0241196 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.023535 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0229429 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0222188 |
| RPL34 | ribosomal protein L34 | -0.0220407 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0220385 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0217287 |
| CDK12 | cyclin-dependent kinase 12 | -0.0212467 |
| RPS13 | ribosomal protein S13 | -0.0211691 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0210929 |
| ZNF217 | zinc finger protein 217 | -0.0208964 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.0203445 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0201893 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0201767 |
| FAM171B | family with sequence similarity 171, member B | -0.0199385 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0198894 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.019766 |
| SQSTM1 | sequestosome 1 | -0.0195645 |
| RFPL4B | ret finger protein-like 4B | -0.0193327 |
| TXNRD1 | thioredoxin reductase 1 | -0.0191515 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.019046 |
| NF1 | neurofibromin 1 | -0.0190272 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0188578 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0186782 |
| HLA-C | major histocompatibility complex, class I, C | -0.0185851 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0183974 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0183936 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0181565 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0179275 |
| PCDH17 | protocadherin 17 | -0.0176483 |
| BRCC3 | BRCA1/BRCA2-containing complex, subunit 3 | -0.017416 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0173485 |
| UBC | ubiquitin C | -0.0173202 |
| RSF1 | remodeling and spacing factor 1 | -0.0168261 |
| BEX3 | brain expressed X-linked 3 | -0.0167329 |
| TBCA | tubulin folding cofactor A | -0.0164225 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0163874 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0162737 |
| CCDC102B | coiled-coil domain containing 102B | -0.0162722 |
| MYADM | myeloid-associated differentiation marker | -0.0160706 |
| AHNAK | AHNAK nucleoprotein | -0.0160408 |
| RPS24 | ribosomal protein S24 | -0.0160398 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0158001 |
| S100A10 | S100 calcium binding protein A10 | -0.0157441 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0157343 |
| SAMD11 | sterile alpha motif domain containing 11 | -0.0155605 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.015521 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.015501 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0154604 |
| RPL31 | ribosomal protein L31 | -0.0153858 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0153057 |
| FUS | FUS RNA binding protein | -0.0153049 |
| HMGB1 | high mobility group box 1 | -0.0151788 |
| RPL19 | ribosomal protein L19 | -0.0151151 |
| STMN1 | stathmin 1 | -0.0147512 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0146613 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0146142 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0145812 |
| CDIN1 | CDAN1 interacting nuclease 1 | -0.0145784 |
| CTPS1 | CTP synthase 1 | -0.0145568 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0145474 |
| CCDC138 | coiled-coil domain containing 138 | -0.014535 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.0142663 |
| EPHA3 | EPH receptor A3 | -0.014263 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0142522 |
