| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.11791 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.108809 |
| HDAC9 | histone deacetylase 9 | 0.0954459 |
| RPS8 | ribosomal protein S8 | 0.0622267 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0577283 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0570873 |
| RPS12 | ribosomal protein S12 | 0.0516981 |
| RPL35A | ribosomal protein L35a | 0.051502 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0506409 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0492717 |
| TMF1 | TATA element modulatory factor 1 | 0.0432288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0431868 |
| RPS3 | ribosomal protein S3 | 0.0430679 |
| RPS2 | ribosomal protein S2 | 0.0426149 |
| TXNRD1 | thioredoxin reductase 1 | 0.0424215 |
| DUSP4 | dual specificity phosphatase 4 | 0.0418858 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0416842 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0415283 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0413653 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0397972 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039378 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0388869 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0378683 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.037373 |
| RPL37A | ribosomal protein L37a | 0.0367415 |
| BMP2K | BMP2 inducible kinase | 0.0350841 |
| PDGFC | platelet derived growth factor C | 0.0345456 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0343289 |
| NCKAP1 | NCK-associated protein 1 | 0.0341235 |
| GOLGA4 | golgin A4 | 0.0339249 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0335692 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.03323 |
| JMJD1C | jumonji domain containing 1C | 0.0331266 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0330167 |
| PYGB | phosphorylase, glycogen; brain | 0.0327907 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0327538 |
| KIF5B | kinesin family member 5B | 0.0327195 |
| ANXA1 | annexin A1 | 0.0323968 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031936 |
| VMP1 | vacuole membrane protein 1 | 0.0318459 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0317247 |
| CRY1 | cryptochrome circadian clock 1 | 0.031691 |
| RACK1 | receptor for activated C kinase 1 | 0.0310639 |
| PGK1 | phosphoglycerate kinase 1 | 0.0305388 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0303824 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0300738 |
| KLF6 | Kruppel-like factor 6 | 0.0297337 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0296059 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0289697 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0284597 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0284407 |
| MT2A | metallothionein 2A | 0.0280836 |
| NUP153 | nucleoporin 153kDa | 0.0277439 |
| FLNB | filamin B, beta | 0.0274277 |
| RTN4 | reticulon 4 | 0.0272648 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0266252 |
| EZR | ezrin | 0.026482 |
| ZNF608 | zinc finger protein 608 | 0.0259114 |
| PLXNA1 | plexin A1 | 0.0259005 |
| CUL3 | cullin 3 | 0.025808 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.025666 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025586 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.025372 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0253014 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0251026 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0250638 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0246784 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0246259 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0246189 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.024609 |
| TMEM65 | transmembrane protein 65 | 0.0244398 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0243461 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0242995 |
| ZNF148 | zinc finger protein 148 | 0.0240967 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240323 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.023865 |
| PDZD8 | PDZ domain containing 8 | 0.0238399 |
| RPL37 | ribosomal protein L37 | 0.0235623 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0232362 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0231185 |
| FLNA | filamin A, alpha | 0.0230592 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0223708 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.0223636 |
| BRD4 | bromodomain containing 4 | 0.0223286 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0223224 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0219758 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0218048 |
| XPO6 | exportin 6 | 0.0217245 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0215998 |
| ZNF292 | zinc finger protein 292 | 0.0212888 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0211236 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.021038 |
| COG5 | component of oligomeric golgi complex 5 | 0.0209461 |
| RPL26 | ribosomal protein L26 | 0.0207486 |
| SET | SET nuclear proto-oncogene | 0.020649 |
| SGMS1 | sphingomyelin synthase 1 | 0.0206432 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0206322 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0205655 |
| ATF4 | activating transcription factor 4 | 0.0204897 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0203557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.21661 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135882 |
| VCL | vinculin | -0.131442 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.124414 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109537 |
| PKM | pyruvate kinase, muscle | -0.0804449 |
| BMP10 | bone morphogenetic protein 10 | -0.0784033 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0744473 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0733606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0725189 |
| PTMA | prothymosin, alpha | -0.0678268 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0628926 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0570501 |
| FOXP1 | forkhead box P1 | -0.0550603 |
| FHIT | fragile histidine triad | -0.054728 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0547007 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0537857 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0533258 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0522375 |
| GLI3 | GLI family zinc finger 3 | -0.051879 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0515271 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0482394 |
| RPS6 | ribosomal protein S6 | -0.0468008 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0459629 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0445903 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0444374 |
| RHOA | ras homolog family member A | -0.0430924 |
| RAD51B | RAD51 paralog B | -0.0429368 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0429023 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0404791 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0404091 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0398764 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.039847 |
| FUS | FUS RNA binding protein | -0.0392583 |
| POTEF | POTE ankyrin domain family, member F | -0.0389109 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0374367 |
| RRBP1 | ribosome binding protein 1 | -0.0355569 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0354831 |
| GLI2 | GLI family zinc finger 2 | -0.0354599 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0352448 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0350666 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0346209 |
| TMSB4X | thymosin beta 4, X-linked | -0.0342755 |
| EXOC4 | exocyst complex component 4 | -0.0327445 |
| RPS19 | ribosomal protein S19 | -0.0323643 |
| CANX | calnexin | -0.0322681 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0322469 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0320548 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0315641 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0315548 |
| GSE1 | Gse1 coiled-coil protein | -0.0310216 |
| S100A10 | S100 calcium binding protein A10 | -0.0304071 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0302866 |
| MYO5C | myosin VC | -0.0300983 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0298138 |
| RPS21 | ribosomal protein S21 | -0.0297861 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0295101 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0292521 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0280898 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0279937 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027797 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0276271 |
| NFIA | nuclear factor I/A | -0.0276063 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0272006 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0271361 |
| RPS24 | ribosomal protein S24 | -0.0269159 |
| RPL28 | ribosomal protein L28 | -0.0268146 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0267683 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.026429 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0263237 |
| NEBL | nebulette | -0.025762 |
| RPS11 | ribosomal protein S11 | -0.0256716 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0254733 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0253011 |
| RPLP0 | ribosomal protein, large, P0 | -0.0252981 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0252799 |
| RPS23 | ribosomal protein S23 | -0.0250767 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0248096 |
| PDE7B | phosphodiesterase 7B | -0.0247145 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0246951 |
| RIGI | RNA sensor RIG-I | -0.0246387 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0244771 |
| TUBB | tubulin, beta class I | -0.0244039 |
| AEBP2 | AE binding protein 2 | -0.0238705 |
| INTS6 | integrator complex subunit 6 | -0.0238304 |
| ZNF217 | zinc finger protein 217 | -0.0237723 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.0236512 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0235328 |
| HMGB1 | high mobility group box 1 | -0.023391 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0227911 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0225871 |
| SRPK2 | SRSF protein kinase 2 | -0.0225278 |
| SETD5 | SET domain containing 5 | -0.0224265 |
| RBM39 | RNA binding motif protein 39 | -0.0223556 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0222532 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0220961 |
| PTMS | parathymosin | -0.0220354 |
| RPL21 | ribosomal protein L21 | -0.0220335 |
| GNAS | GNAS complex locus | -0.0219449 |
