| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.182366 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.142112 |
| NDRG1 | N-myc downstream regulated 1 | 0.120798 |
| IL6 | interleukin 6 | 0.104986 |
| MT2A | metallothionein 2A | 0.0883129 |
| EGFR | epidermal growth factor receptor | 0.0877253 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0770985 |
| KYNU | kynureninase | 0.0754214 |
| PRELID2 | PRELI domain containing 2 | 0.073918 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0718484 |
| CD44 | CD44 molecule (Indian blood group) | 0.0643376 |
| HMGA2 | high mobility group AT-hook 2 | 0.0616652 |
| FNDC3B | fibronectin type III domain containing 3B | 0.059727 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0557323 |
| COL5A1 | collagen, type V, alpha 1 | 0.0553758 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0540458 |
| NRXN3 | neurexin 3 | 0.0532898 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0522012 |
| HLA-B | major histocompatibility complex, class I, B | 0.0506491 |
| FLNA | filamin A, alpha | 0.0502254 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0489608 |
| RUNX1 | runt-related transcription factor 1 | 0.0471633 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0467156 |
| STC1 | stanniocalcin 1 | 0.0465537 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0451332 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0450582 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0447169 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0443835 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0441783 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0439591 |
| IGF2 | insulin-like growth factor 2 | 0.0410282 |
| FAM13A | family with sequence similarity 13, member A | 0.0407251 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0393045 |
| FMNL2 | formin-like 2 | 0.0392102 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0391992 |
| VEGFA | vascular endothelial growth factor A | 0.038988 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0389723 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.038958 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0373772 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.037186 |
| ZNF148 | zinc finger protein 148 | 0.037144 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0369721 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0364527 |
| VEGFC | vascular endothelial growth factor C | 0.0363104 |
| RPS12 | ribosomal protein S12 | 0.0360365 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0360023 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0356586 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0355657 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0355438 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0351789 |
| SYNPO | synaptopodin | 0.0346937 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0345709 |
| RPS17 | ribosomal protein S17 | 0.0336354 |
| LOX | lysyl oxidase | 0.0335959 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0335912 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0332127 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0326017 |
| RPL11 | ribosomal protein L11 | 0.0319965 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0319349 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0317753 |
| RPS2 | ribosomal protein S2 | 0.0314795 |
| ZNF395 | zinc finger protein 395 | 0.0311763 |
| MSN | moesin | 0.0311009 |
| CDH13 | cadherin 13 | 0.0308064 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0307147 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0303004 |
| VIM | vimentin | 0.030117 |
| GSE1 | Gse1 coiled-coil protein | 0.0292393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0290173 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0285289 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.028415 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.028235 |
| FN1 | fibronectin 1 | 0.0276869 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0275775 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0275221 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0274856 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0270838 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0270445 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.026842 |
| YEATS2 | YEATS domain containing 2 | 0.0267823 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0261951 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0260827 |
| SYNJ2 | synaptojanin 2 | 0.0260218 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0259093 |
| SMYD3 | SET and MYND domain containing 3 | 0.025682 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0256705 |
| ZNF638 | zinc finger protein 638 | 0.025648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0254498 |
| TPR | translocated promoter region, nuclear basket protein | 0.0254156 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.025198 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0248059 |
| NBAS | neuroblastoma amplified sequence | 0.0247405 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.024026 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0236262 |
| RBM25 | RNA binding motif protein 25 | 0.0235607 |
| RPS3 | ribosomal protein S3 | 0.0230659 |
| RAI14 | retinoic acid induced 14 | 0.0229813 |
| FOSL1 | FOS-like antigen 1 | 0.0229458 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0229086 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0228353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.22916 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.168583 |
| COL1A1 | collagen, type I, alpha 1 | -0.166818 |
| COL1A2 | collagen, type I, alpha 2 | -0.126828 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12059 |
| PTMA | prothymosin, alpha | -0.095484 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.082992 |
| CANX | calnexin | -0.081655 |
| AHNAK | AHNAK nucleoprotein | -0.078844 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0737207 |
| SDC4 | syndecan 4 | -0.0678537 |
| OGA | O-GlcNAcase | -0.0499565 |
| CAVIN1 | caveolae associated protein 1 | -0.0494055 |
| HLA-C | major histocompatibility complex, class I, C | -0.0487662 |
| UBC | ubiquitin C | -0.0487128 |
| CALU | calumenin | -0.0465737 |
| RRBP1 | ribosome binding protein 1 | -0.0463833 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0461803 |
| ANXA2 | annexin A2 | -0.0427487 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.039862 |
| TUBB | tubulin, beta class I | -0.0384536 |
| TPM4 | tropomyosin 4 | -0.0373237 |
| VCL | vinculin | -0.0368918 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0341918 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0338221 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0337965 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0336422 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.033298 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328181 |
| RHEB | Ras homolog enriched in brain | -0.032419 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.032343 |
| PRSS23 | protease, serine, 23 | -0.0322034 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0321888 |
| THY1 | Thy-1 cell surface antigen | -0.031991 |
| TFG | TRK-fused gene | -0.0309979 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0305327 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0300328 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0292342 |
| ENO1 | enolase 1, (alpha) | -0.0289042 |
| S100A10 | S100 calcium binding protein A10 | -0.0288679 |
| RLF | rearranged L-myc fusion | -0.0287108 |
| COL5A2 | collagen, type V, alpha 2 | -0.0286259 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0286236 |
| HDLBP | high density lipoprotein binding protein | -0.0285873 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0283228 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281045 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.027827 |
| DSTN | destrin (actin depolymerizing factor) | -0.0270154 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0270094 |
| HMGB2 | high mobility group box 2 | -0.0270082 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0266799 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0262761 |
| H3-3B | H3.3 histone B | -0.0258893 |
| TMEM41B | transmembrane protein 41B | -0.0257315 |
| GOLGA4 | golgin A4 | -0.0254939 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0254352 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0253885 |
| PDE10A | phosphodiesterase 10A | -0.0253525 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0253385 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0252731 |
| HM13 | histocompatibility (minor) 13 | -0.0250161 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0250087 |
| PALLD | palladin, cytoskeletal associated protein | -0.0249006 |
| HBP1 | HMG-box transcription factor 1 | -0.0246564 |
| KLHDC10 | kelch domain containing 10 | -0.0246334 |
| YIPF5 | Yip1 domain family, member 5 | -0.024626 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0244172 |
| IKBIP | IKBKB interacting protein | -0.0243525 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0242392 |
| GNAS | GNAS complex locus | -0.0241781 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0241574 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0241529 |
| ADM | adrenomedullin | -0.0241097 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0239839 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0239392 |
| CD109 | CD109 molecule | -0.0238349 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0237005 |
| FSTL1 | follistatin-like 1 | -0.0234916 |
| CD99 | CD99 molecule | -0.0232812 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0231993 |
| RPS23 | ribosomal protein S23 | -0.0229054 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0228058 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0226517 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0226122 |
| RAB10 | RAB10, member RAS oncogene family | -0.0224956 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0224887 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0223301 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0222804 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0222194 |
| RHOA | ras homolog family member A | -0.0221661 |
| ZNF207 | zinc finger protein 207 | -0.0220657 |
| DIAPH3 | diaphanous-related formin 3 | -0.021956 |
| RPS24 | ribosomal protein S24 | -0.0218663 |
| USP3 | ubiquitin specific peptidase 3 | -0.0218207 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0217911 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0217156 |
| CLIC4 | chloride intracellular channel 4 | -0.0215497 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212392 |
| EMP1 | epithelial membrane protein 1 | -0.0212113 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0210531 |
