| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANGPTL4 | angiopoietin-like 4 | 0.117885 |
| FNDC3B | fibronectin type III domain containing 3B | 0.100695 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0955516 |
| RIGI | RNA sensor RIG-I | 0.0904289 |
| MT2A | metallothionein 2A | 0.0895063 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0888095 |
| IGF2 | insulin-like growth factor 2 | 0.0850687 |
| NDRG1 | N-myc downstream regulated 1 | 0.0776782 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0590891 |
| TMSB10 | thymosin beta 10 | 0.055876 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0558271 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0501845 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.049682 |
| FMNL2 | formin-like 2 | 0.0496371 |
| DTNA | dystrobrevin, alpha | 0.0444377 |
| EGR1 | early growth response 1 | 0.044058 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0439964 |
| EGFR | epidermal growth factor receptor | 0.0428192 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0425181 |
| JMJD1C | jumonji domain containing 1C | 0.0422381 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0415688 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0413851 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.040573 |
| RPS3 | ribosomal protein S3 | 0.0405572 |
| SQSTM1 | sequestosome 1 | 0.0403419 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0403114 |
| INTS6 | integrator complex subunit 6 | 0.0398253 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0393554 |
| RACK1 | receptor for activated C kinase 1 | 0.0384588 |
| GPC5 | glypican 5 | 0.0378427 |
| ACTN1 | actinin, alpha 1 | 0.0377095 |
| HLA-B | major histocompatibility complex, class I, B | 0.0364569 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0357804 |
| HLA-A | major histocompatibility complex, class I, A | 0.0340641 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0339339 |
| PFN1 | profilin 1 | 0.0334917 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0331564 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0327091 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0323376 |
| RPL35A | ribosomal protein L35a | 0.0323305 |
| RPS12 | ribosomal protein S12 | 0.0319144 |
| RPL23 | ribosomal protein L23 | 0.0316611 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0313799 |
| GGT7 | gamma-glutamyltransferase 7 | 0.031258 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0312576 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0306397 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0305809 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0299518 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0294655 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0293088 |
| GLRX | glutaredoxin (thioltransferase) | 0.0284676 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.02834 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.028184 |
| VIM | vimentin | 0.0279402 |
| TXNIP | thioredoxin interacting protein | 0.0278667 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276702 |
| BRD4 | bromodomain containing 4 | 0.0273921 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0270626 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.026663 |
| CTBP2 | C-terminal binding protein 2 | 0.0264794 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0264725 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0263895 |
| FLNA | filamin A, alpha | 0.0261851 |
| PRSS23 | protease, serine, 23 | 0.0260523 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0260204 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0259005 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0258301 |
| IER3 | immediate early response 3 | 0.0254679 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0252819 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0252301 |
| RPS17 | ribosomal protein S17 | 0.0252235 |
| SKIL | SKI-like proto-oncogene | 0.0252232 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0250392 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248526 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0247626 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0247149 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0246666 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0246321 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0245098 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0240911 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0238292 |
| MT1X | metallothionein 1X | 0.0237175 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0234291 |
| SATB2 | SATB homeobox 2 | 0.023303 |
| CLDN1 | claudin 1 | 0.0230959 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0228927 |
| MCL1 | myeloid cell leukemia 1 | 0.0228586 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.02269 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0223943 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0223771 |
| SVIL | supervillin | 0.022327 |
| ASPH | aspartate beta-hydroxylase | 0.0222623 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0222495 |
| RPS19 | ribosomal protein S19 | 0.0221256 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.02198 |
| HLA-C | major histocompatibility complex, class I, C | 0.0219492 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0219115 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0218993 |
| LAMA5 | laminin, alpha 5 | 0.0217321 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0215217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2639 |
| CENPF | centromere protein F, 350/400kDa | -0.0900589 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0857598 |
| TPX2 | TPX2, microtubule-associated | -0.0807855 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0757096 |
| RBM39 | RNA binding motif protein 39 | -0.0737661 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0637017 |
| GOLGA4 | golgin A4 | -0.0632596 |
| ANLN | anillin, actin binding protein | -0.0596341 |
| SMYD3 | SET and MYND domain containing 3 | -0.0582617 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0548249 |
| PTMA | prothymosin, alpha | -0.0545797 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0515402 |
| DIAPH3 | diaphanous-related formin 3 | -0.0495977 |
| CKAP5 | cytoskeleton associated protein 5 | -0.049228 |
| OSMR | oncostatin M receptor | -0.0486326 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0468912 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0451824 |
| AHNAK | AHNAK nucleoprotein | -0.0449065 |
| MKI67 | marker of proliferation Ki-67 | -0.0435135 |
| PHF20 | PHD finger protein 20 | -0.0425499 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0412405 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0398985 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0392224 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0373622 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0373482 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0369755 |
| LMO7 | LIM domain 7 | -0.0365814 |
| TMEM123 | transmembrane protein 123 | -0.0364058 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0361369 |
| TPM4 | tropomyosin 4 | -0.035983 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0359095 |
| YBX3 | Y box binding protein 3 | -0.0358353 |
| RRBP1 | ribosome binding protein 1 | -0.0356584 |
| CANX | calnexin | -0.03552 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351085 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0350681 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0347537 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.034463 |
| TAOK1 | TAO kinase 1 | -0.0344132 |
| CPNE1 | copine I | -0.0339152 |
| ATM | ATM serine/threonine kinase | -0.0334922 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0330525 |
| NUP58 | nucleoporin 58 | -0.032989 |
| KIF23 | kinesin family member 23 | -0.0328846 |
| CCNB1 | cyclin B1 | -0.0327095 |
| KIAA1328 | KIAA1328 | -0.0325327 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0325304 |
| KIF4A | kinesin family member 4A | -0.03246 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0323797 |
| TXNRD1 | thioredoxin reductase 1 | -0.0323176 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0319318 |
| AURKA | aurora kinase A | -0.0315136 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0307459 |
| ABI2 | abl-interactor 2 | -0.0306494 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.030572 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0305384 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0305352 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304658 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0302131 |
| GOLGB1 | golgin B1 | -0.0301459 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0301058 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0300088 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.029947 |
| PRR11 | proline rich 11 | -0.0298162 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0297906 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0297621 |
| OLA1 | Obg-like ATPase 1 | -0.0293898 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0293804 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0292709 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0289572 |
| ECT2 | epithelial cell transforming 2 | -0.028701 |
| NF1 | neurofibromin 1 | -0.0286513 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0282978 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0279435 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0279233 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.027708 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0277029 |
| HJURP | Holliday junction recognition protein | -0.0276961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276404 |
| BRD8 | bromodomain containing 8 | -0.0276384 |
| RPS25 | ribosomal protein S25 | -0.0270362 |
| DEK | DEK proto-oncogene | -0.0270043 |
| HMGB2 | high mobility group box 2 | -0.0268714 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.026864 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0266435 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0266273 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0264097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.026294 |
| TFRC | transferrin receptor | -0.0261941 |
| KIF18B | kinesin family member 18B | -0.0261747 |
| WDR45B | WD repeat domain 45B | -0.0261704 |
| USP22 | ubiquitin specific peptidase 22 | -0.0258352 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0258098 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0256573 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0254147 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0253153 |
| LDHA | lactate dehydrogenase A | -0.0252904 |
| IL6ST | interleukin 6 signal transducer | -0.0252799 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0252131 |
