| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Terfenadine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Terfenadine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.131568 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.122843 |
| NDRG1 | N-myc downstream regulated 1 | 0.122388 |
| STC2 | stanniocalcin 2 | 0.115968 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0878285 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0869188 |
| MT2A | metallothionein 2A | 0.0792934 |
| TMEM156 | transmembrane protein 156 | 0.0772135 |
| EFNA5 | ephrin-A5 | 0.0644809 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0629455 |
| DUSP6 | dual specificity phosphatase 6 | 0.0600472 |
| TMSB4X | thymosin beta 4, X-linked | 0.0590774 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.058656 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0580933 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0578779 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0568022 |
| HMGA2 | high mobility group AT-hook 2 | 0.0567569 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0563566 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0535688 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0524589 |
| FTL | ferritin, light polypeptide | 0.0523742 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.049998 |
| RASAL2 | RAS protein activator like 2 | 0.0495611 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0494292 |
| FAM13A | family with sequence similarity 13, member A | 0.0488406 |
| SFTPA2 | surfactant protein A2 | 0.0457543 |
| SYT1 | synaptotagmin I | 0.0422346 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0416168 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0413354 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0408437 |
| TXNIP | thioredoxin interacting protein | 0.0403424 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0403052 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0400524 |
| RAI14 | retinoic acid induced 14 | 0.0398298 |
| OXR1 | oxidation resistance 1 | 0.0393117 |
| RPL35A | ribosomal protein L35a | 0.0392684 |
| RPS27 | ribosomal protein S27 | 0.0388953 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0373532 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0340175 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0330732 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0327685 |
| GPC6 | glypican 6 | 0.0325318 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0322311 |
| SFXN1 | sideroflexin 1 | 0.0322026 |
| RPS8 | ribosomal protein S8 | 0.0320125 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0310244 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0309509 |
| STC1 | stanniocalcin 1 | 0.0305951 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0305847 |
| HLA-B | major histocompatibility complex, class I, B | 0.0302874 |
| JMJD1C | jumonji domain containing 1C | 0.0301571 |
| VEGFA | vascular endothelial growth factor A | 0.0301451 |
| RPL37A | ribosomal protein L37a | 0.0298585 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0297519 |
| RPS19 | ribosomal protein S19 | 0.0294488 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0294448 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294136 |
| ITGA1 | integrin, alpha 1 | 0.029274 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0288784 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0288096 |
| LMNA | lamin A/C | 0.0285468 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0284702 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0281152 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0274555 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0274069 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.027063 |
| INSIG1 | insulin induced gene 1 | 0.0270423 |
| RTN4 | reticulon 4 | 0.0270136 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0269517 |
| RPL26 | ribosomal protein L26 | 0.0269006 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0262776 |
| RPL36 | ribosomal protein L36 | 0.0259574 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0257897 |
| RPL37 | ribosomal protein L37 | 0.0255393 |
| GOLGA4 | golgin A4 | 0.0255385 |
| CCDC88A | coiled-coil domain containing 88A | 0.0250607 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0246837 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0246272 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.02444 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0240027 |
| TPR | translocated promoter region, nuclear basket protein | 0.0235924 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0235856 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0235438 |
| EMP1 | epithelial membrane protein 1 | 0.023486 |
| SIRT1 | sirtuin 1 | 0.0233096 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0232915 |
| KLF6 | Kruppel-like factor 6 | 0.0230067 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0227609 |
| NRG1 | neuregulin 1 | 0.0227103 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0226959 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0226919 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0225929 |
| FAT1 | FAT atypical cadherin 1 | 0.0222531 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0222193 |
| HDAC9 | histone deacetylase 9 | 0.0221405 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0218076 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0217465 |
| RPL11 | ribosomal protein L11 | 0.0215547 |
| CD109 | CD109 molecule | 0.0210601 |
| BPTF | bromodomain PHD finger transcription factor | 0.0210497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.16607 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.145199 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135043 |
| UBC | ubiquitin C | -0.132726 |
| CANX | calnexin | -0.101824 |
| PTMA | prothymosin, alpha | -0.0901271 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0794507 |
| RPS27A | ribosomal protein S27a | -0.0745577 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0653964 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0576077 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0571723 |
| CENPF | centromere protein F, 350/400kDa | -0.0540814 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0526606 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0517614 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.050938 |
| TMSB10 | thymosin beta 10 | -0.0508629 |
| VCL | vinculin | -0.050158 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0496803 |
| RHEB | Ras homolog enriched in brain | -0.0479044 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0475353 |
| AHNAK | AHNAK nucleoprotein | -0.0466234 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0454385 |
| SMAD3 | SMAD family member 3 | -0.0445273 |
| ACTN4 | actinin, alpha 4 | -0.0424376 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0422702 |
| COPA | coatomer protein complex, subunit alpha | -0.0413016 |
| OGA | O-GlcNAcase | -0.0412141 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0410881 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0399607 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0397303 |
| VMP1 | vacuole membrane protein 1 | -0.0395379 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0388025 |
| RBM39 | RNA binding motif protein 39 | -0.0387343 |
| PKM | pyruvate kinase, muscle | -0.0378387 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0371079 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0362769 |
| RNF145 | ring finger protein 145 | -0.0356089 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.03495 |
| SUCO | SUN domain containing ossification factor | -0.0343076 |
| POTEF | POTE ankyrin domain family, member F | -0.0336635 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0335241 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0331757 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0331671 |
| ADD3 | adducin 3 (gamma) | -0.0329164 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0325962 |
| GLIS3 | GLIS family zinc finger 3 | -0.0324337 |
| AEBP2 | AE binding protein 2 | -0.0318693 |
| APP | amyloid beta (A4) precursor protein | -0.0316954 |
| ETNK1 | ethanolamine kinase 1 | -0.0309473 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0301575 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0301462 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0301079 |
| TFG | TRK-fused gene | -0.0296778 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294713 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0294489 |
| SDC4 | syndecan 4 | -0.0290958 |
| PCBP2 | poly(rC) binding protein 2 | -0.0290032 |
| INTS6 | integrator complex subunit 6 | -0.0288955 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0286842 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0284676 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0284592 |
| RANBP2 | RAN binding protein 2 | -0.0279089 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0278116 |
| NEK7 | NIMA-related kinase 7 | -0.0276466 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0271039 |
| CCDC138 | coiled-coil domain containing 138 | -0.0268703 |
| PTK2 | protein tyrosine kinase 2 | -0.0264211 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0261753 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.026028 |
| HDLBP | high density lipoprotein binding protein | -0.0259835 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0258664 |
| RPS5 | ribosomal protein S5 | -0.0257205 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.025163 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0251175 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0250315 |
| ZNF207 | zinc finger protein 207 | -0.024579 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0243941 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0242601 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.024095 |
| FAM20C | family with sequence similarity 20, member C | -0.0240142 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0240055 |
| XPO1 | exportin 1 | -0.023937 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0239304 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0237502 |
| THBS1 | thrombospondin 1 | -0.0237131 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0237081 |
| RPS24 | ribosomal protein S24 | -0.0236494 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0235455 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0235312 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0235059 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0233323 |
| CUL3 | cullin 3 | -0.0233077 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0232456 |
| AHR | aryl hydrocarbon receptor | -0.0231945 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | -0.0231407 |
| YAP1 | Yes-associated protein 1 | -0.0229517 |
| SERINC3 | serine incorporator 3 | -0.0229007 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0226798 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0226613 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0225653 |
