| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.189825 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.157056 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.13748 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.131876 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0882143 |
| FBN1 | fibrillin 1 | 0.0854172 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0849096 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0830716 |
| LOX | lysyl oxidase | 0.08202 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0767794 |
| COL3A1 | collagen, type III, alpha 1 | 0.0754688 |
| FLNB | filamin B, beta | 0.0666481 |
| THBS2 | thrombospondin 2 | 0.0645568 |
| PRELID2 | PRELI domain containing 2 | 0.0643682 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0632597 |
| SBF2 | SET binding factor 2 | 0.0560183 |
| ATP13A3 | ATPase type 13A3 | 0.0520948 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0484115 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0466665 |
| LOXL2 | lysyl oxidase-like 2 | 0.0465004 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0460599 |
| GPC6 | glypican 6 | 0.0457504 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0449374 |
| NAV2 | neuron navigator 2 | 0.0446752 |
| DST | dystonin | 0.0431887 |
| YEATS2 | YEATS domain containing 2 | 0.0412689 |
| APP | amyloid beta (A4) precursor protein | 0.0408343 |
| ENO1 | enolase 1, (alpha) | 0.0405704 |
| COL1A2 | collagen, type I, alpha 2 | 0.039917 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0388893 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0383748 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0374432 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0369644 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0367576 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0366368 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0365886 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0364815 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0364571 |
| SP3 | Sp3 transcription factor | 0.0364496 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0360278 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0353699 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0349233 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0338909 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0335614 |
| FLNA | filamin A, alpha | 0.0334804 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0332349 |
| OGA | O-GlcNAcase | 0.033067 |
| ZNF292 | zinc finger protein 292 | 0.0325648 |
| C1D | C1D nuclear receptor corepressor | 0.0321523 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.03201 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0315128 |
| MYOF | myoferlin | 0.0306061 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.030469 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0302002 |
| RUNX1 | runt-related transcription factor 1 | 0.0301137 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0297504 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0296776 |
| NBEAL1 | neurobeachin-like 1 | 0.0294325 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.029371 |
| LDHA | lactate dehydrogenase A | 0.0293418 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0292214 |
| STC1 | stanniocalcin 1 | 0.0288893 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0284651 |
| STK10 | serine/threonine kinase 10 | 0.0284043 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0282369 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0282066 |
| COL5A2 | collagen, type V, alpha 2 | 0.0275061 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0273746 |
| MTSS1 | metastasis suppressor 1 | 0.0273083 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0268 |
| ARRDC3 | arrestin domain containing 3 | 0.0267732 |
| HMGB2 | high mobility group box 2 | 0.026743 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0267238 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0266393 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0261511 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0260562 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0257248 |
| SMYD3 | SET and MYND domain containing 3 | 0.0255806 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0254595 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0249507 |
| AFDN | afadin, adherens junction formation factor | 0.0248736 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0247153 |
| UBQLN1 | ubiquilin 1 | 0.024336 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.024099 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0233408 |
| MYO9A | myosin IXA | 0.0232944 |
| SERINC1 | serine incorporator 1 | 0.0232605 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.023183 |
| TMOD1 | tropomodulin 1 | 0.0229616 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0229189 |
| RAI1 | retinoic acid induced 1 | 0.022909 |
| MB21D2 | Mab-21 domain containing 2 | 0.02277 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0226862 |
| CD109 | CD109 molecule | 0.0223749 |
| SEPTIN9 | septin 9 | 0.0223021 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0222927 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0222701 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0219556 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0218727 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349778 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.286318 |
| S100A10 | S100 calcium binding protein A10 | -0.119779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.116304 |
| AHNAK | AHNAK nucleoprotein | -0.109674 |
| MAP1B | microtubule-associated protein 1B | -0.0952747 |
| POTEF | POTE ankyrin domain family, member F | -0.0945264 |
| UBC | ubiquitin C | -0.0924487 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0785067 |
| TMSB10 | thymosin beta 10 | -0.0715641 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0639214 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0619039 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0614357 |
| NDRG1 | N-myc downstream regulated 1 | -0.0609736 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0574504 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0574096 |
| CDH13 | cadherin 13 | -0.0559795 |
| ACTG1 | actin gamma 1 | -0.0536986 |
| RIGI | RNA sensor RIG-I | -0.0536343 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0527745 |
| HLA-B | major histocompatibility complex, class I, B | -0.0520468 |
| MT1X | metallothionein 1X | -0.050418 |
| FN1 | fibronectin 1 | -0.0499612 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0490879 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0436654 |
| TAGLN2 | transgelin 2 | -0.040923 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0405308 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.039914 |
| TAOK1 | TAO kinase 1 | -0.0390893 |
| S100A6 | S100 calcium binding protein A6 | -0.038203 |
| FSTL1 | follistatin-like 1 | -0.0381214 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0365618 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0360939 |
| CANX | calnexin | -0.0359183 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0347358 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0337425 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.030991 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0309054 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0306852 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304972 |
| CCND1 | cyclin D1 | -0.0301327 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0301062 |
| TMSB4X | thymosin beta 4, X-linked | -0.0298339 |
| VIM | vimentin | -0.0297479 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0296352 |
| PFN1 | profilin 1 | -0.0290526 |
| TAPBP | TAP binding protein (tapasin) | -0.029004 |
| RPL35A | ribosomal protein L35a | -0.0289275 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.028343 |
| COPA | coatomer protein complex, subunit alpha | -0.0282947 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0275995 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0275669 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0271231 |
| SQSTM1 | sequestosome 1 | -0.0269573 |
| IL7R | interleukin 7 receptor | -0.0269154 |
| ADAR | adenosine deaminase, RNA-specific | -0.0266791 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0260507 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0260024 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0256949 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.025028 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0248752 |
| RPS15 | ribosomal protein S15 | -0.0247858 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024148 |
| JAZF1 | JAZF zinc finger 1 | -0.0239194 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0237864 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0233203 |
| ACLY | ATP citrate lyase | -0.0231183 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0229365 |
| THY1 | Thy-1 cell surface antigen | -0.0227354 |
| IRF1 | interferon regulatory factor 1 | -0.0221648 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0220856 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0219458 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0217688 |
| PCDH7 | protocadherin 7 | -0.0213077 |
| RPL28 | ribosomal protein L28 | -0.0210135 |
| CYTH3 | cytohesin 3 | -0.0209097 |
| PLXNA2 | plexin A2 | -0.0208286 |
| MX2 | MX dynamin-like GTPase 2 | -0.0208134 |
| FBXO11 | F-box protein 11 | -0.0207162 |
| TGFB1 | transforming growth factor, beta 1 | -0.020449 |
| LMNA | lamin A/C | -0.0202988 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0201805 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0200339 |
| TPM1 | tropomyosin 1 (alpha) | -0.0198006 |
| HLA-C | major histocompatibility complex, class I, C | -0.0195105 |
| INTS6 | integrator complex subunit 6 | -0.0193901 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0193739 |
| RPS6 | ribosomal protein S6 | -0.0193641 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0192476 |
| RND3 | Rho family GTPase 3 | -0.0189628 |
| RPS11 | ribosomal protein S11 | -0.0188203 |
| RPS23 | ribosomal protein S23 | -0.0187679 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.018676 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0185715 |
| SETX | senataxin | -0.0185116 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0184203 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.018418 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0182438 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0182216 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0180543 |
