| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.130545 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0917405 |
| AREG | amphiregulin | 0.0917014 |
| RPS12 | ribosomal protein S12 | 0.0530853 |
| ANXA1 | annexin A1 | 0.0444989 |
| EHBP1 | EH domain binding protein 1 | 0.0384515 |
| RPS3 | ribosomal protein S3 | 0.0384402 |
| RPS7 | ribosomal protein S7 | 0.035458 |
| DST | dystonin | 0.0324774 |
| PCBP2 | poly(rC) binding protein 2 | 0.0300229 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0296879 |
| YAP1 | Yes-associated protein 1 | 0.0295973 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292832 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0284539 |
| VMP1 | vacuole membrane protein 1 | 0.0283289 |
| HMGA2 | high mobility group AT-hook 2 | 0.0276986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0260925 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0256852 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248946 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0248482 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247498 |
| ENO1 | enolase 1, (alpha) | 0.0241314 |
| SYT1 | synaptotagmin I | 0.022565 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0224904 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0222375 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0221111 |
| PCDH9 | protocadherin 9 | 0.0219576 |
| MKI67 | marker of proliferation Ki-67 | 0.021596 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0206786 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0203023 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0202816 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0199334 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.019886 |
| DTNA | dystrobrevin, alpha | 0.0198116 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0197388 |
| HDGF | hepatoma-derived growth factor | 0.0197022 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0190358 |
| RPS2 | ribosomal protein S2 | 0.0188394 |
| SESN2 | sestrin 2 | 0.0184378 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.018207 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.018159 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0180467 |
| EPHA6 | EPH receptor A6 | 0.0178555 |
| RPL21 | ribosomal protein L21 | 0.0176082 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0173787 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0173731 |
| TPM3 | tropomyosin 3 | 0.0172695 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0170202 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0160706 |
| PRELID2 | PRELI domain containing 2 | 0.0157019 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0155416 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0153644 |
| TBK1 | TANK-binding kinase 1 | 0.0153579 |
| LRRC23 | leucine rich repeat containing 23 | 0.0152075 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0151138 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0151047 |
| RPS17 | ribosomal protein S17 | 0.0148535 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0147896 |
| NUP58 | nucleoporin 58 | 0.0147568 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.014743 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0145536 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0143422 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0142446 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.014216 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.014146 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0138567 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0138017 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0135551 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0135074 |
| NFIB | nuclear factor I/B | 0.0134878 |
| SET | SET nuclear proto-oncogene | 0.0134473 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0133834 |
| EFNA5 | ephrin-A5 | 0.0133192 |
| PLK2 | polo-like kinase 2 | 0.0132777 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0131693 |
| JMJD1C | jumonji domain containing 1C | 0.0131645 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0131083 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0130215 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0129611 |
| HDAC9 | histone deacetylase 9 | 0.0129201 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0128545 |
| RPS26 | ribosomal protein S26 | 0.0128507 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.012662 |
| HYOU1 | hypoxia up-regulated 1 | 0.0126092 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0125733 |
| ZNF146 | zinc finger protein 146 | 0.0123658 |
| PEG10 | paternally expressed 10 | 0.0122056 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0121978 |
| INTS6 | integrator complex subunit 6 | 0.0120298 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0119746 |
| RPL37A | ribosomal protein L37a | 0.0119383 |
| MCL1 | myeloid cell leukemia 1 | 0.0119378 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0118692 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0117802 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0117523 |
| KSR2 | kinase suppressor of ras 2 | 0.0117356 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0117098 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0116402 |
| YTHDC1 | YTH domain containing 1 | 0.0116067 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0115971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.321029 |
| ACTG1 | actin gamma 1 | -0.105035 |
| MYL12B | myosin, light chain 12B, regulatory | -0.081346 |
| RPL35A | ribosomal protein L35a | -0.0749549 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0745743 |
| AHNAK | AHNAK nucleoprotein | -0.0619682 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0550246 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0548612 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0526895 |
| PCDH7 | protocadherin 7 | -0.0520051 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0518881 |
| TMSB10 | thymosin beta 10 | -0.0518532 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0516781 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0516003 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0501942 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0482234 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.048105 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0450491 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0446742 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0434312 |
| BCHE | butyrylcholinesterase | -0.0417763 |
| RPS21 | ribosomal protein S21 | -0.0402361 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0400726 |
| FUS | FUS RNA binding protein | -0.0375899 |
| ZNF217 | zinc finger protein 217 | -0.0374702 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0370608 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0362225 |
| RPL34 | ribosomal protein L34 | -0.036167 |
| YBX1 | Y box binding protein 1 | -0.0361332 |
| LMO7 | LIM domain 7 | -0.0360225 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0355162 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0328054 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0326346 |
| GCG | glucagon | -0.0322798 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0321868 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0319355 |
| TMEM41B | transmembrane protein 41B | -0.0318483 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0316503 |
| RPL38 | ribosomal protein L38 | -0.0300965 |
| RPS15 | ribosomal protein S15 | -0.0299216 |
| CANX | calnexin | -0.0295989 |
| RPL8 | ribosomal protein L8 | -0.0294517 |
| RPS24 | ribosomal protein S24 | -0.029053 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0289877 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0284341 |
| VIM | vimentin | -0.0283095 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0282037 |
| UBC | ubiquitin C | -0.0280538 |
| MGAT4C | MGAT4 family, member C | -0.0278097 |
| DEK | DEK proto-oncogene | -0.0277062 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0276201 |
| NLGN1 | neuroligin 1 | -0.0275573 |
| TMEM123 | transmembrane protein 123 | -0.0275159 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0271342 |
| H1-0 | H1.0 linker histone | -0.0269252 |
| RPS23 | ribosomal protein S23 | -0.0268486 |
| CLDN1 | claudin 1 | -0.0263119 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0258129 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0257436 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0254925 |
| RPLP1 | ribosomal protein, large, P1 | -0.0254251 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0250693 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0250229 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0249677 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0243207 |
| TXNRD1 | thioredoxin reductase 1 | -0.0243132 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0242987 |
| CCND1 | cyclin D1 | -0.0237167 |
| TUBB | tubulin, beta class I | -0.0232222 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0228386 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.022342 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0213874 |
| CXADR | coxsackie virus and adenovirus receptor | -0.020945 |
| CDK12 | cyclin-dependent kinase 12 | -0.0209308 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0209102 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0204396 |
| RPL32 | ribosomal protein L32 | -0.0204079 |
| ZNF638 | zinc finger protein 638 | -0.0201365 |
| RPL11 | ribosomal protein L11 | -0.0201041 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0200655 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0200267 |
| MMP12 | matrix metallopeptidase 12 | -0.0200121 |
| RBMX | RNA binding motif protein, X-linked | -0.0199692 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0199508 |
| RPS11 | ribosomal protein S11 | -0.0198492 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0197646 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0197575 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0197219 |
| RPL4 | ribosomal protein L4 | -0.0197102 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0197095 |
| GNAS | GNAS complex locus | -0.0196735 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0196414 |
| THOC1 | THO complex 1 | -0.0194984 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0192225 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0192128 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0191156 |
| CALR | calreticulin | -0.0190258 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.018152 |
| KHSRP | KH-type splicing regulatory protein | -0.0180466 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.0177539 |
