| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0575106 |
| PRELID2 | PRELI domain containing 2 | 0.0422879 |
| ASPH | aspartate beta-hydroxylase | 0.0417497 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0408417 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0304006 |
| RPS3 | ribosomal protein S3 | 0.0269379 |
| CALR | calreticulin | 0.0267939 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0257933 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0252805 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0242415 |
| RPS7 | ribosomal protein S7 | 0.0241187 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0229732 |
| STC1 | stanniocalcin 1 | 0.0227332 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0227086 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0226995 |
| DST | dystonin | 0.022426 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217627 |
| EFNA5 | ephrin-A5 | 0.021641 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0212262 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0208733 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0206091 |
| ANLN | anillin, actin binding protein | 0.0202791 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0202118 |
| RUNX1 | runt-related transcription factor 1 | 0.0195034 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0194839 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0193144 |
| ATM | ATM serine/threonine kinase | 0.0192071 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0190561 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0190536 |
| SRP54 | signal recognition particle 54kDa | 0.0189245 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0186656 |
| HYOU1 | hypoxia up-regulated 1 | 0.0182466 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0180848 |
| STX16 | syntaxin 16 | 0.0180135 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0179681 |
| ITGA6 | integrin, alpha 6 | 0.0179309 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0178581 |
| CALU | calumenin | 0.0178579 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0176907 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0174653 |
| RAD51B | RAD51 paralog B | 0.0172514 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0172155 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0170937 |
| LMO7 | LIM domain 7 | 0.0170092 |
| FRMD4A | FERM domain containing 4A | 0.0169789 |
| MEOX2 | mesenchyme homeobox 2 | 0.0168708 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0168656 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0167358 |
| TET1 | tet methylcytosine dioxygenase 1 | 0.0165401 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0164711 |
| USP11 | ubiquitin specific peptidase 11 | 0.016435 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0161986 |
| OXR1 | oxidation resistance 1 | 0.0161263 |
| PIR | pirin (iron-binding nuclear protein) | 0.016096 |
| MGA | MGA, MAX dimerization protein | 0.0160253 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0157317 |
| KIZ | kizuna centrosomal protein | 0.0156912 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0156542 |
| SPATA13 | spermatogenesis associated 13 | 0.0156502 |
| FMN1 | formin 1 | 0.0156202 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0155874 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.0155009 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0154676 |
| PRDX3 | peroxiredoxin 3 | 0.0152375 |
| RBM26 | RNA binding motif protein 26 | 0.0152209 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0152139 |
| PCDH7 | protocadherin 7 | 0.0151933 |
| PEG10 | paternally expressed 10 | 0.0151004 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0150935 |
| MTAP | methylthioadenosine phosphorylase | 0.0150884 |
| AFDN | afadin, adherens junction formation factor | 0.0150415 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.014948 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0149407 |
| MYO10 | myosin X | 0.0148989 |
| CD109 | CD109 molecule | 0.014889 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0147768 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0147704 |
| TMEM123 | transmembrane protein 123 | 0.014757 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0147393 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0146423 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0145443 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0145251 |
| OGA | O-GlcNAcase | 0.0145214 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0144047 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0144 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0143637 |
| EREG | epiregulin | 0.0142931 |
| FAM169A | family with sequence similarity 169, member A | 0.0142314 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0142303 |
| DPYD | dihydropyrimidine dehydrogenase | 0.014228 |
| VIRMA | vir like m6A methyltransferase associated | 0.0141772 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0141736 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0140456 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0140359 |
| CCNL1 | cyclin L1 | 0.0140212 |
| PLIN2 | perilipin 2 | 0.0139443 |
| PHF21A | PHD finger protein 21A | 0.0138998 |
| ZNF432 | zinc finger protein 432 | 0.013887 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0138611 |
| SMYD3 | SET and MYND domain containing 3 | 0.0138462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.195988 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178624 |
| MT2A | metallothionein 2A | -0.0754794 |
| JMJD1C | jumonji domain containing 1C | -0.0750435 |
| ACTG1 | actin gamma 1 | -0.067466 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0673239 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.065594 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0641182 |
| NFIB | nuclear factor I/B | -0.0633125 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0630847 |
| RPS6 | ribosomal protein S6 | -0.0630312 |
| SBF2 | SET binding factor 2 | -0.0621528 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0616764 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0607859 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0604407 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0596515 |
| MED13L | mediator complex subunit 13-like | -0.0579315 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0578512 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0575511 |
| ERBIN | erbb2 interacting protein | -0.0564197 |
| UBC | ubiquitin C | -0.0562196 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0559024 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0538439 |
| SRPK2 | SRSF protein kinase 2 | -0.0517655 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.051183 |
| CTBP2 | C-terminal binding protein 2 | -0.0503973 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0500716 |
| DEK | DEK proto-oncogene | -0.0497066 |
| MEST | mesoderm specific transcript | -0.0486343 |
| SEPTIN11 | septin 11 | -0.0481434 |
| PARD3 | par-3 family cell polarity regulator | -0.0478013 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0472482 |
| RPS23 | ribosomal protein S23 | -0.047164 |
| BCOR | BCL6 corepressor | -0.0465831 |
| HMGA1 | high mobility group AT-hook 1 | -0.0464189 |
| ZNF292 | zinc finger protein 292 | -0.045916 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0458315 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0448351 |
| CADM2 | cell adhesion molecule 2 | -0.0446102 |
| PHIP | pleckstrin homology domain interacting protein | -0.0443153 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0436813 |
| GOLGA4 | golgin A4 | -0.0436356 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0420634 |
| RPS19 | ribosomal protein S19 | -0.041361 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.04111 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0402718 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.040231 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0399645 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0394809 |
| BBX | bobby sox homolog (Drosophila) | -0.0394073 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0390778 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0389744 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0387911 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0385064 |
| CDK6 | cyclin-dependent kinase 6 | -0.038354 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0383291 |
| RPS11 | ribosomal protein S11 | -0.0380444 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0379397 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0377104 |
| RPLP1 | ribosomal protein, large, P1 | -0.0375782 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0374718 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0373039 |
| GPHN | gephyrin | -0.0371499 |
| PCM1 | pericentriolar material 1 | -0.0367855 |
| DMXL1 | Dmx-like 1 | -0.0366272 |
| RPS8 | ribosomal protein S8 | -0.0364408 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0360053 |
| TCF12 | transcription factor 12 | -0.0359378 |
| UST | uronyl-2-sulfotransferase | -0.035766 |
| PKM | pyruvate kinase, muscle | -0.0357251 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0353979 |
| GSE1 | Gse1 coiled-coil protein | -0.0353595 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0352274 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0349624 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.034915 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0346043 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0345958 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0344986 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0344881 |
| ZFHX3 | zinc finger homeobox 3 | -0.0341659 |
| VEGFA | vascular endothelial growth factor A | -0.0339685 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0337866 |
| YBX1 | Y box binding protein 1 | -0.0337414 |
| RNF216 | ring finger protein 216 | -0.033593 |
| CANX | calnexin | -0.033449 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0326865 |
| BRD4 | bromodomain containing 4 | -0.0324323 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0321551 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0319682 |
| RPL32 | ribosomal protein L32 | -0.0316852 |
| PTK2 | protein tyrosine kinase 2 | -0.0315516 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0314897 |
| ENAH | enabled homolog (Drosophila) | -0.0312548 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0312453 |
| RPS27A | ribosomal protein S27a | -0.0311837 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0309144 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0309004 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308136 |
| AOPEP | aminopeptidase O (putative) | -0.0306245 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.030427 |
