| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.170117 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0894015 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0710641 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0673145 |
| NUP58 | nucleoporin 58 | 0.0613034 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0610911 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0577477 |
| ENO1 | enolase 1, (alpha) | 0.0527027 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0519073 |
| LDHA | lactate dehydrogenase A | 0.0500893 |
| HELZ | helicase with zinc finger | 0.0500461 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0494067 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0469697 |
| KIAA1958 | KIAA1958 | 0.0460702 |
| ZNF292 | zinc finger protein 292 | 0.0459438 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0456413 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0446661 |
| HMGB2 | high mobility group box 2 | 0.0437717 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0437503 |
| XPO1 | exportin 1 | 0.0397198 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0390959 |
| BBX | bobby sox homolog (Drosophila) | 0.0378262 |
| TXNRD1 | thioredoxin reductase 1 | 0.0364401 |
| SHROOM3 | shroom family member 3 | 0.0359557 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0359206 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0346137 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0338656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0337625 |
| PRELID2 | PRELI domain containing 2 | 0.0332392 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0326995 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0326147 |
| TNPO3 | transportin 3 | 0.032564 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0318599 |
| IPO7 | importin 7 | 0.0314468 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0309821 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0308559 |
| TENM2 | teneurin transmembrane protein 2 | 0.030267 |
| SMYD3 | SET and MYND domain containing 3 | 0.030239 |
| ATRN | attractin | 0.0297066 |
| CENPF | centromere protein F, 350/400kDa | 0.0295174 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0292031 |
| MKI67 | marker of proliferation Ki-67 | 0.0291949 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0290562 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0282991 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0282615 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0281874 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0280137 |
| TBK1 | TANK-binding kinase 1 | 0.0279554 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0278834 |
| OGA | O-GlcNAcase | 0.0276812 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0276747 |
| SET | SET nuclear proto-oncogene | 0.0276365 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0273892 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0269338 |
| CNN2 | calponin 2 | 0.0267826 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0267016 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0264692 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0258449 |
| RPL22L1 | ribosomal protein L22-like 1 | 0.0257088 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0253231 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0251701 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0249541 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0247294 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0247021 |
| FAM162A | family with sequence similarity 162, member A | 0.0244815 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0244268 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.024362 |
| RPS12 | ribosomal protein S12 | 0.0242911 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0239548 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0238207 |
| LPIN2 | lipin 2 | 0.0234966 |
| LMNB1 | lamin B1 | 0.0233705 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0233325 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0231877 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0231346 |
| YEATS2 | YEATS domain containing 2 | 0.0231002 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0230445 |
| GPHN | gephyrin | 0.0230372 |
| ZNF608 | zinc finger protein 608 | 0.023006 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0230042 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0229007 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0227201 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0226527 |
| RTN4 | reticulon 4 | 0.0226217 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0225713 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0224772 |
| LATS2 | large tumor suppressor kinase 2 | 0.0223509 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0222541 |
| KIF5B | kinesin family member 5B | 0.0222365 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0222147 |
| FAM13A | family with sequence similarity 13, member A | 0.022203 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0219384 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0219084 |
| EGR1 | early growth response 1 | 0.0218829 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0218563 |
| PNN | pinin, desmosome associated protein | 0.021622 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0215674 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0215471 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0215186 |
| KIAA1328 | KIAA1328 | 0.0213982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18044 |
| ACTG1 | actin gamma 1 | -0.114904 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0982975 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0837574 |
| TENM3 | teneurin transmembrane protein 3 | -0.0803124 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0692095 |
| RPL35A | ribosomal protein L35a | -0.0529417 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0451059 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0420501 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0416439 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.040496 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0392167 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0388057 |
| RPL34 | ribosomal protein L34 | -0.0368118 |
| RPS11 | ribosomal protein S11 | -0.0361662 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0360554 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.035265 |
| RPS23 | ribosomal protein S23 | -0.0350861 |
| MLIP | muscular LMNA-interacting protein | -0.0349721 |
| RPL8 | ribosomal protein L8 | -0.0345652 |
| UBC | ubiquitin C | -0.0338419 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0336766 |
| RIGI | RNA sensor RIG-I | -0.0335117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0329948 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0324601 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0315205 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299154 |
| PCNX4 | pecanex 4 | -0.0297889 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0296533 |
| BNC2 | basonuclin 2 | -0.0288161 |
| RPS21 | ribosomal protein S21 | -0.0275983 |
| SETX | senataxin | -0.0275383 |
| GNAS | GNAS complex locus | -0.0274267 |
| CCDC138 | coiled-coil domain containing 138 | -0.0265564 |
| RAD51B | RAD51 paralog B | -0.0258372 |
| RPLP1 | ribosomal protein, large, P1 | -0.025314 |
| RPS29 | ribosomal protein S29 | -0.0251617 |
| CANX | calnexin | -0.024994 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | -0.0249426 |
| HMGB1 | high mobility group box 1 | -0.0247301 |
| RPS10 | ribosomal protein S10 | -0.0245006 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0244236 |
| AHI1 | Abelson helper integration site 1 | -0.0243558 |
| WLS | wntless Wnt ligand secretion mediator | -0.0241326 |
| ZNF644 | zinc finger protein 644 | -0.0232984 |
| RPS24 | ribosomal protein S24 | -0.0229324 |
| RPS19 | ribosomal protein S19 | -0.0229104 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0223245 |
| RPS15 | ribosomal protein S15 | -0.0222868 |
| CADM2 | cell adhesion molecule 2 | -0.0219237 |
| RPL37 | ribosomal protein L37 | -0.0217892 |
| TBCA | tubulin folding cofactor A | -0.0216819 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0215626 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0214497 |
| RCC1 | regulator of chromosome condensation 1 | -0.0213414 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0210314 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0209815 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0208507 |
| RPL31 | ribosomal protein L31 | -0.0208206 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0207399 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.020416 |
| ATF4 | activating transcription factor 4 | -0.0202289 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0201553 |
| UBAP2 | ubiquitin associated protein 2 | -0.0200909 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200796 |
| REEP3 | receptor accessory protein 3 | -0.0200128 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0200019 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | -0.0199134 |
| RBMX | RNA binding motif protein, X-linked | -0.0199053 |
| RPL9 | ribosomal protein L9 | -0.0197348 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.0196317 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0194057 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.019328 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0188173 |
| RPL38 | ribosomal protein L38 | -0.0184303 |
| RPL11 | ribosomal protein L11 | -0.0183443 |
| RHOA | ras homolog family member A | -0.0183322 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0183288 |
| INTS6 | integrator complex subunit 6 | -0.0182962 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0180037 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0178747 |
| FASN | fatty acid synthase | -0.0177951 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0177561 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0177298 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0174534 |
| CDK12 | cyclin-dependent kinase 12 | -0.0174439 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0174176 |
| COMMD10 | COMM domain containing 10 | -0.0173668 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0173414 |
| ZNF33A | zinc finger protein 33A | -0.0168994 |
| HDAC4 | histone deacetylase 4 | -0.016898 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0168754 |
| RHEB | Ras homolog enriched in brain | -0.0168079 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0167991 |
| NEBL | nebulette | -0.0167755 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0166164 |
| FUS | FUS RNA binding protein | -0.0165475 |
| PMP22 | peripheral myelin protein 22 | -0.0164498 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0164397 |
| SIK2 | salt-inducible kinase 2 | -0.0163476 |
