| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.203127 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.081561 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0777429 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608924 |
| FN1 | fibronectin 1 | 0.0604647 |
| ENO1 | enolase 1, (alpha) | 0.0590271 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.057935 |
| VIM | vimentin | 0.0556806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498052 |
| RPS12 | ribosomal protein S12 | 0.048408 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0455058 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.044372 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0423827 |
| RPS3 | ribosomal protein S3 | 0.041091 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0390802 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0389846 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0384867 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0375217 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0374524 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0360937 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0359906 |
| FOSL1 | FOS-like antigen 1 | 0.0356546 |
| NUP58 | nucleoporin 58 | 0.0351397 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0343265 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.034162 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.03131 |
| A2M | alpha-2-macroglobulin | 0.0310877 |
| RNF145 | ring finger protein 145 | 0.0305284 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0301266 |
| ADM | adrenomedullin | 0.0300846 |
| RPL36 | ribosomal protein L36 | 0.0298921 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0298014 |
| LDHA | lactate dehydrogenase A | 0.0295606 |
| TMEM178B | transmembrane protein 178B | 0.0293325 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0290211 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0288429 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0280045 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.027742 |
| RPLP2 | ribosomal protein, large, P2 | 0.0275079 |
| PTMA | prothymosin, alpha | 0.0274688 |
| PRELID2 | PRELI domain containing 2 | 0.0259609 |
| CDC73 | cell division cycle 73 | 0.0258357 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0252462 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0251986 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.0247942 |
| PHF21A | PHD finger protein 21A | 0.0246363 |
| RPS8 | ribosomal protein S8 | 0.0243398 |
| ARRDC3 | arrestin domain containing 3 | 0.0241735 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0241514 |
| SLMAP | sarcolemma associated protein | 0.0239687 |
| GOLGA4 | golgin A4 | 0.023823 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0237556 |
| RPL26 | ribosomal protein L26 | 0.023737 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.023667 |
| TNPO3 | transportin 3 | 0.0235364 |
| CD109 | CD109 molecule | 0.0227729 |
| ZNF292 | zinc finger protein 292 | 0.0227486 |
| COG5 | component of oligomeric golgi complex 5 | 0.0227308 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0227018 |
| RPL19 | ribosomal protein L19 | 0.0226053 |
| RPS16 | ribosomal protein S16 | 0.0224402 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0220264 |
| CABIN1 | calcineurin binding protein 1 | 0.0217182 |
| FBXO32 | F-box protein 32 | 0.0217141 |
| DICER1 | dicer 1, ribonuclease type III | 0.0215775 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0213567 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0211978 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0208929 |
| RPL37A | ribosomal protein L37a | 0.0205328 |
| AFDN | afadin, adherens junction formation factor | 0.020326 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.020001 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0197229 |
| WDR45B | WD repeat domain 45B | 0.0196043 |
| RACK1 | receptor for activated C kinase 1 | 0.0191168 |
| RPS2 | ribosomal protein S2 | 0.0186428 |
| RPS27 | ribosomal protein S27 | 0.0185106 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0184511 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0184475 |
| HMGB2 | high mobility group box 2 | 0.0184272 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0183087 |
| TPR | translocated promoter region, nuclear basket protein | 0.0182497 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0178974 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0178731 |
| FTL | ferritin, light polypeptide | 0.0178575 |
| MLEC | malectin | 0.0177375 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.017705 |
| HYOU1 | hypoxia up-regulated 1 | 0.017505 |
| FAM13A | family with sequence similarity 13, member A | 0.0173738 |
| YBX1 | Y box binding protein 1 | 0.0173487 |
| BRD2 | bromodomain containing 2 | 0.0170441 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.0170338 |
| AHR | aryl hydrocarbon receptor | 0.0163496 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.016329 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0163046 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0162901 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0162319 |
| SEM1 | SEM1 26S proteasome subunit | 0.0162142 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0161354 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0161153 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0161048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.393035 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.201164 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.153787 |
| FMN1 | formin 1 | -0.143068 |
| NLGN1 | neuroligin 1 | -0.138741 |
| GPC6 | glypican 6 | -0.134183 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.122745 |
| ACTG1 | actin gamma 1 | -0.108514 |
| ASPH | aspartate beta-hydroxylase | -0.105202 |
| HLA-B | major histocompatibility complex, class I, B | -0.0983362 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0837662 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0829522 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0783598 |
| VGF | VGF nerve growth factor inducible | -0.0731284 |
| FRMD4A | FERM domain containing 4A | -0.0710868 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0555381 |
| PTK2 | protein tyrosine kinase 2 | -0.0529072 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0517387 |
| DCT | dopachrome tautomerase | -0.0514738 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0498501 |
| CALD1 | caldesmon 1 | -0.0494681 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0463745 |
| EHBP1 | EH domain binding protein 1 | -0.0459949 |
| SCFD2 | sec1 family domain containing 2 | -0.0448455 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0434234 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.043371 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0433235 |
| CUX1 | cut-like homeobox 1 | -0.0432868 |
| NAV3 | neuron navigator 3 | -0.04309 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0419534 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0417879 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0415741 |
| CTTNBP2 | cortactin binding protein 2 | -0.039784 |
| CDK14 | cyclin-dependent kinase 14 | -0.0391313 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0389113 |
| CENPF | centromere protein F, 350/400kDa | -0.037799 |
| PCDH7 | protocadherin 7 | -0.0371981 |
| ZNF704 | zinc finger protein 704 | -0.0370948 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0364814 |
| TRIM2 | tripartite motif containing 2 | -0.0363274 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0362739 |
| DST | dystonin | -0.0362346 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0357486 |
| CALU | calumenin | -0.0356654 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0354299 |
| AHNAK | AHNAK nucleoprotein | -0.0350131 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0349608 |
| CD63 | CD63 molecule | -0.0346996 |
| MACROD2 | MACRO domain containing 2 | -0.0337421 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0332631 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0331778 |
| UBC | ubiquitin C | -0.0328411 |
| LAMB1 | laminin, beta 1 | -0.0328042 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0325409 |
| S100A10 | S100 calcium binding protein A10 | -0.0324396 |
| RAD51B | RAD51 paralog B | -0.0318154 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0312074 |
| MYO10 | myosin X | -0.0310147 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0296411 |
| TULP4 | tubby like protein 4 | -0.0293943 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0292205 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0291699 |
| HMGA2 | high mobility group AT-hook 2 | -0.0288381 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0288315 |
| GHR | growth hormone receptor | -0.0286244 |
| DIAPH2 | diaphanous-related formin 2 | -0.0285181 |
| PTCHD4 | patched domain containing 4 | -0.0284612 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0281819 |
| CCND1 | cyclin D1 | -0.0281391 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0276989 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0276102 |
| FHIT | fragile histidine triad | -0.0274181 |
| CADM1 | cell adhesion molecule 1 | -0.0273008 |
| HMCN1 | hemicentin 1 | -0.0271056 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0267054 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0266946 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0265585 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0265189 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0264415 |
| INSIG1 | insulin induced gene 1 | -0.0264093 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0253553 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.02534 |
| PDE10A | phosphodiesterase 10A | -0.0251501 |
| VCL | vinculin | -0.0249824 |
| POTEF | POTE ankyrin domain family, member F | -0.0247738 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0247606 |
| ZNF638 | zinc finger protein 638 | -0.0247297 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0244992 |
| ARFGEF3 | ARFGEF family member 3 | -0.0244233 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.024314 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.024148 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0241371 |
| FUS | FUS RNA binding protein | -0.0237547 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0237021 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0236735 |
| ATF6 | activating transcription factor 6 | -0.0235617 |
| TMEM123 | transmembrane protein 123 | -0.0234529 |
| NAV1 | neuron navigator 1 | -0.0232219 |
| TAGLN2 | transgelin 2 | -0.0231756 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0228401 |
