| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.119953 |
| ENO1 | enolase 1, (alpha) | 0.0705365 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0542035 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0486483 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0478076 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.045064 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0447116 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0411211 |
| EHBP1 | EH domain binding protein 1 | 0.0404819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0389169 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0370481 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0359561 |
| DST | dystonin | 0.0350788 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0322832 |
| RAD51B | RAD51 paralog B | 0.032024 |
| APP | amyloid beta (A4) precursor protein | 0.0303265 |
| MCL1 | myeloid cell leukemia 1 | 0.0294565 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0290207 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0290149 |
| DTNA | dystrobrevin, alpha | 0.0288386 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0278891 |
| ZNF148 | zinc finger protein 148 | 0.0265067 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0263724 |
| RPS3 | ribosomal protein S3 | 0.0258405 |
| RPS12 | ribosomal protein S12 | 0.0254804 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0253114 |
| ANGPTL4 | angiopoietin-like 4 | 0.0249983 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0245744 |
| HMGA2 | high mobility group AT-hook 2 | 0.0241259 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.022523 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0224386 |
| NCKAP5 | NCK-associated protein 5 | 0.0222988 |
| KIF13B | kinesin family member 13B | 0.0222431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0219414 |
| PRELID2 | PRELI domain containing 2 | 0.0214052 |
| ATXN1 | ataxin 1 | 0.0209745 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0208218 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0207933 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020685 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0203621 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0200157 |
| HPCAL1 | hippocalcin-like 1 | 0.0199146 |
| HMGB2 | high mobility group box 2 | 0.0197032 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.0193723 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0192644 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0192199 |
| SYNRG | synergin, gamma | 0.0183995 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0182894 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0181566 |
| ITGA6 | integrin, alpha 6 | 0.0181215 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0177944 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0176685 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0176479 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0176409 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0176365 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0174116 |
| SRP54 | signal recognition particle 54kDa | 0.0173367 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0172867 |
| RPS17 | ribosomal protein S17 | 0.0172654 |
| PDZD8 | PDZ domain containing 8 | 0.0172629 |
| FNIP1 | folliculin interacting protein 1 | 0.0172388 |
| RPS7 | ribosomal protein S7 | 0.0170305 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0170222 |
| VCAN | versican | 0.0169151 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0168365 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0168245 |
| MKI67 | marker of proliferation Ki-67 | 0.0168116 |
| FLNB | filamin B, beta | 0.0168096 |
| NPC1 | Niemann-Pick disease, type C1 | 0.016425 |
| FAM13A | family with sequence similarity 13, member A | 0.0162869 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0162113 |
| LIPH | lipase, member H | 0.0161121 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0160852 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0160751 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0160462 |
| TGFB2 | transforming growth factor, beta 2 | 0.0158882 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.015716 |
| FLNA | filamin A, alpha | 0.0155675 |
| TPM3 | tropomyosin 3 | 0.0154766 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0152945 |
| SLC35F5 | solute carrier family 35, member F5 | 0.015239 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0152035 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0151255 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0150855 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0150808 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0150514 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0149734 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0149468 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.014903 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0148958 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0147857 |
| CMIP | c-Maf inducing protein | 0.0147617 |
| NBEAL1 | neurobeachin-like 1 | 0.0146956 |
| TMF1 | TATA element modulatory factor 1 | 0.0146716 |
| BCL2L1 | BCL2-like 1 | 0.0146714 |
| EFNA5 | ephrin-A5 | 0.0146136 |
| NOTCH2 | notch 2 | 0.0145737 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.014295 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0142474 |
| MKRN1 | makorin ring finger protein 1 | 0.0141762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349027 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.213577 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.180292 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.159776 |
| UBC | ubiquitin C | -0.156512 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139999 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.134269 |
| ACTG1 | actin gamma 1 | -0.129531 |
| TMSB4X | thymosin beta 4, X-linked | -0.121349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10387 |
| PTMA | prothymosin, alpha | -0.103268 |
| MT1X | metallothionein 1X | -0.0949963 |
| HLA-B | major histocompatibility complex, class I, B | -0.0924218 |
| RPL35A | ribosomal protein L35a | -0.0758007 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0733878 |
| AHNAK | AHNAK nucleoprotein | -0.071895 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0716849 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0699877 |
| POTEF | POTE ankyrin domain family, member F | -0.0674762 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0653207 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0645446 |
| ANXA2 | annexin A2 | -0.0639852 |
| RBM39 | RNA binding motif protein 39 | -0.063565 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0626554 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0604853 |
| CANX | calnexin | -0.0602841 |
| S100A10 | S100 calcium binding protein A10 | -0.0584068 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0582414 |
| NDRG1 | N-myc downstream regulated 1 | -0.0575285 |
| PGK1 | phosphoglycerate kinase 1 | -0.0571342 |
| IER3 | immediate early response 3 | -0.0564113 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0558658 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0556673 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0534477 |
| MMP7 | matrix metallopeptidase 7 | -0.0519895 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0507898 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0500791 |
| SPAG9 | sperm associated antigen 9 | -0.0494598 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0494258 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0476138 |
| RPLP1 | ribosomal protein, large, P1 | -0.0467135 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0462423 |
| USP3 | ubiquitin specific peptidase 3 | -0.0455339 |
| RPL34 | ribosomal protein L34 | -0.0440706 |
| H1-0 | H1.0 linker histone | -0.0430761 |
| YBX1 | Y box binding protein 1 | -0.0416621 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0415096 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0412442 |
| RPS23 | ribosomal protein S23 | -0.0403398 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0398553 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0367284 |
| HMGA1 | high mobility group AT-hook 1 | -0.0353568 |
| TPM1 | tropomyosin 1 (alpha) | -0.0351926 |
| RPS6 | ribosomal protein S6 | -0.0351742 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0348776 |
| CP | ceruloplasmin (ferroxidase) | -0.0348341 |
| TAPBP | TAP binding protein (tapasin) | -0.0346409 |
| APOL2 | apolipoprotein L, 2 | -0.0345596 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.033974 |
| GNAS | GNAS complex locus | -0.033847 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0336433 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0331067 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0330856 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0330731 |
| RPS24 | ribosomal protein S24 | -0.0330226 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0327175 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0323747 |
| G0S2 | G0/G1 switch 2 | -0.0314174 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0313635 |
| KRT8 | keratin 8, type II | -0.0312399 |
| FAM3C | family with sequence similarity 3, member C | -0.0311239 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0306453 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0302435 |
| CD2AP | CD2-associated protein | -0.0301753 |
| RPS21 | ribosomal protein S21 | -0.0301616 |
| CCNI | cyclin I | -0.0300299 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300146 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0295753 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0294284 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0293763 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0288205 |
| DSG2 | desmoglein 2 | -0.0287684 |
| RPS19 | ribosomal protein S19 | -0.028523 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0284507 |
| RPL4 | ribosomal protein L4 | -0.0283893 |
| DEK | DEK proto-oncogene | -0.02825 |
| RRBP1 | ribosome binding protein 1 | -0.0278826 |
| WAC | WW domain containing adaptor with coiled-coil | -0.027449 |
| APOL1 | apolipoprotein L, 1 | -0.0274472 |
| TFG | TRK-fused gene | -0.0274084 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0273057 |
| IRF1 | interferon regulatory factor 1 | -0.0271226 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0269188 |
| KRT19 | keratin 19, type I | -0.0264577 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0263229 |
| RPL23 | ribosomal protein L23 | -0.0262936 |
| TMSB10 | thymosin beta 10 | -0.0262875 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0261517 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0260789 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260141 |
