| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.136602 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.109723 |
| IGF2 | insulin-like growth factor 2 | 0.091916 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0871313 |
| MEF2A | myocyte enhancer factor 2A | 0.082045 |
| ENO1 | enolase 1, (alpha) | 0.070995 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0678799 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0619811 |
| PCDH9 | protocadherin 9 | 0.0618915 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0604006 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0590465 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0572825 |
| VIM | vimentin | 0.0563732 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0553043 |
| B2M | beta-2-microglobulin | 0.0547892 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0526513 |
| RPS3 | ribosomal protein S3 | 0.0486105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0484144 |
| RPS12 | ribosomal protein S12 | 0.0471906 |
| CENPF | centromere protein F, 350/400kDa | 0.0468033 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0441221 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.043211 |
| MKI67 | marker of proliferation Ki-67 | 0.0416919 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0409972 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0391 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0382196 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0378196 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0371589 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0360043 |
| LDHA | lactate dehydrogenase A | 0.0332096 |
| PKM | pyruvate kinase, muscle | 0.0331415 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0323573 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0317919 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0312563 |
| DST | dystonin | 0.031207 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0311138 |
| ZNF148 | zinc finger protein 148 | 0.0305353 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0304463 |
| FLNB | filamin B, beta | 0.0302276 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.02998 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0297698 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0295935 |
| SMC4 | structural maintenance of chromosomes 4 | 0.028974 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0277226 |
| WDR45B | WD repeat domain 45B | 0.0275791 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0273874 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271947 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0271149 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0270996 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0269773 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0269305 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0266881 |
| VEGFA | vascular endothelial growth factor A | 0.0263416 |
| RPL36 | ribosomal protein L36 | 0.0261474 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0255111 |
| FTL | ferritin, light polypeptide | 0.0254468 |
| VCAN | versican | 0.0252512 |
| PCBP2 | poly(rC) binding protein 2 | 0.0250247 |
| YTHDC1 | YTH domain containing 1 | 0.0249506 |
| FNBP1 | formin binding protein 1 | 0.0245271 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0244762 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0242447 |
| ANGPTL4 | angiopoietin-like 4 | 0.0241048 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0238783 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0238295 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0236267 |
| FRMD5 | FERM domain containing 5 | 0.0235776 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.023471 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0231672 |
| SBF2 | SET binding factor 2 | 0.0231542 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0229661 |
| FAM162A | family with sequence similarity 162, member A | 0.0227998 |
| PLAT | plasminogen activator, tissue | 0.0227681 |
| RPL31 | ribosomal protein L31 | 0.0226496 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0225427 |
| RTN4 | reticulon 4 | 0.0223671 |
| DTNA | dystrobrevin, alpha | 0.022184 |
| BPTF | bromodomain PHD finger transcription factor | 0.0220954 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0220517 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0219435 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0218274 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0218128 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0216298 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0215064 |
| EFNA5 | ephrin-A5 | 0.0214611 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0213638 |
| RPL7 | ribosomal protein L7 | 0.0211832 |
| PHF21A | PHD finger protein 21A | 0.0209556 |
| RPL21 | ribosomal protein L21 | 0.0209381 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0208257 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0207908 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0207611 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0204841 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0204647 |
| RPL36A | ribosomal protein L36a | 0.0203651 |
| ZNF146 | zinc finger protein 146 | 0.0202636 |
| TPM3 | tropomyosin 3 | 0.0201491 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0198483 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.019814 |
| HMGA2 | high mobility group AT-hook 2 | 0.0195679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.161315 |
| ACTG1 | actin gamma 1 | -0.157494 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126018 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11434 |
| LPIN1 | lipin 1 | -0.109 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106086 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0948019 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0907692 |
| FMN1 | formin 1 | -0.0828721 |
| VCL | vinculin | -0.0759824 |
| COL3A1 | collagen, type III, alpha 1 | -0.0727221 |
| AOPEP | aminopeptidase O (putative) | -0.0642648 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0641957 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0614444 |
| RPL38 | ribosomal protein L38 | -0.059392 |
| ZNF804A | zinc finger protein 804A | -0.0571816 |
| NRG1 | neuregulin 1 | -0.057025 |
| SYT1 | synaptotagmin I | -0.054674 |
| CANX | calnexin | -0.054283 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.053676 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532579 |
| RPL4 | ribosomal protein L4 | -0.0528155 |
| PTMA | prothymosin, alpha | -0.0509367 |
| AHNAK | AHNAK nucleoprotein | -0.0494685 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0485329 |
| FRMD4A | FERM domain containing 4A | -0.0479709 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.046941 |
| TRIB2 | tribbles pseudokinase 2 | -0.046406 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0456602 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0444999 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0442985 |
| LMNA | lamin A/C | -0.0431347 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0430942 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0426071 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0418764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0415455 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0413918 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0400292 |
| RPL35A | ribosomal protein L35a | -0.0398344 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0396205 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0381222 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0379329 |
| CCND1 | cyclin D1 | -0.0377315 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0376721 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0375038 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0370952 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0360141 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0357989 |
| CDK12 | cyclin-dependent kinase 12 | -0.0356425 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0354534 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0339743 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0337079 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0332507 |
| RPL34 | ribosomal protein L34 | -0.0330883 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0325348 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.032464 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.03232 |
| IER3 | immediate early response 3 | -0.0317527 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0316433 |
| GPHN | gephyrin | -0.0314251 |
| HDLBP | high density lipoprotein binding protein | -0.0312622 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0309179 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0309068 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0308699 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0307911 |
| ARF1 | ADP-ribosylation factor 1 | -0.0295924 |
| THBS1 | thrombospondin 1 | -0.0295611 |
| NREP | neuronal regeneration related protein | -0.0293204 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0291532 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0290566 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.028872 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0287904 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0284063 |
| MATR3 | matrin 3 | -0.0283303 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0281982 |
| FOXK2 | forkhead box K2 | -0.0281572 |
| GLCCI1 | glucocorticoid induced 1 | -0.0277841 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0275932 |
| TULP4 | tubby like protein 4 | -0.0275538 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0275134 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0273675 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0272619 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0269758 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269744 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0268665 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0267192 |
| RPL32 | ribosomal protein L32 | -0.0266302 |
| PCNX4 | pecanex 4 | -0.0265568 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0264649 |
| GPATCH8 | G patch domain containing 8 | -0.0264521 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.026422 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.026152 |
| PTK2 | protein tyrosine kinase 2 | -0.0257705 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0257244 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0256515 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.025486 |
| POU2F1 | POU class 2 homeobox 1 | -0.0252132 |
| MSI2 | musashi RNA-binding protein 2 | -0.0250825 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.024911 |
| CADM2 | cell adhesion molecule 2 | -0.0248084 |
