| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0411985 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0399412 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0390444 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0385312 |
| MEIS2 | Meis homeobox 2 | 0.0375961 |
| NDRG1 | N-myc downstream regulated 1 | 0.0368271 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0358001 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0346348 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0307822 |
| ABHD2 | abhydrolase domain containing 2 | 0.0306076 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0304732 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0295206 |
| MUC13 | mucin 13, cell surface associated | 0.027257 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0264356 |
| FOSL2 | FOS-like antigen 2 | 0.0247824 |
| VCL | vinculin | 0.0236847 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0233457 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.022267 |
| RNF43 | ring finger protein 43 | 0.0217814 |
| PTEN | phosphatase and tensin homolog | 0.0213209 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0212581 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0211766 |
| TC2N | tandem C2 domains, nuclear | 0.0211443 |
| DNM2 | dynamin 2 | 0.0210505 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0207097 |
| TXNIP | thioredoxin interacting protein | 0.0199375 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0198368 |
| AREG | amphiregulin | 0.019611 |
| ALPK1 | alpha-kinase 1 | 0.0194143 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0191118 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0189649 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0185427 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0184949 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0180602 |
| MYO10 | myosin X | 0.0179309 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0177127 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0173359 |
| RNF149 | ring finger protein 149 | 0.0171561 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0169603 |
| JUP | junction plakoglobin | 0.0164743 |
| USP54 | ubiquitin specific peptidase 54 | 0.0159306 |
| FHL2 | four and a half LIM domains 2 | 0.0158337 |
| PLIN2 | perilipin 2 | 0.0156189 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.015499 |
| PRELID2 | PRELI domain containing 2 | 0.0153261 |
| NEK7 | NIMA-related kinase 7 | 0.0152647 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0152127 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0151602 |
| HLA-A | major histocompatibility complex, class I, A | 0.0151127 |
| DAND5 | DAN domain family member 5, BMP antagonist | 0.0150863 |
| MKRN1 | makorin ring finger protein 1 | 0.0150586 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0150515 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0150454 |
| PDE10A | phosphodiesterase 10A | 0.0150341 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0148915 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0148601 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.014753 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0147282 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.01467 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0146398 |
| ITGB4 | integrin, beta 4 | 0.01462 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0146124 |
| LIMA1 | LIM domain and actin binding 1 | 0.0145959 |
| CD68 | CD68 molecule | 0.0142553 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0141765 |
| MT2A | metallothionein 2A | 0.0141406 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0141202 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.014091 |
| ERBIN | erbb2 interacting protein | 0.0138645 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0133427 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0133092 |
| KIAA0040 | KIAA0040 | 0.0132786 |
| CORIN | corin, serine peptidase | 0.0130788 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.01301 |
| YAP1 | Yes-associated protein 1 | 0.0129954 |
| TEX9 | testis expressed 9 | 0.0129786 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.012951 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0127982 |
| KIF26B | kinesin family member 26B | 0.0127221 |
| EREG | epiregulin | 0.0127157 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0126573 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0126392 |
| MXI1 | MAX interactor 1, dimerization protein | 0.012612 |
| CCNL1 | cyclin L1 | 0.012576 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.012454 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0124416 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.0124233 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0123839 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0123571 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0122601 |
| TPCN1 | two pore segment channel 1 | 0.0121203 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0120796 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0120442 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0119359 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0118685 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0118021 |
| SP3 | Sp3 transcription factor | 0.0117519 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.0117302 |
| FAT1 | FAT atypical cadherin 1 | 0.011723 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.01156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.237304 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.173721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.17054 |
| UBC | ubiquitin C | -0.163184 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.156086 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.144117 |
| RNF213 | ring finger protein 213 | -0.10825 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100678 |
| RRBP1 | ribosome binding protein 1 | -0.0993365 |
| HLA-B | major histocompatibility complex, class I, B | -0.0991803 |
| CANX | calnexin | -0.0951739 |
| SP100 | SP100 nuclear antigen | -0.0876359 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0874835 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0863158 |
| LYZ | lysozyme | -0.0845172 |
| LMO7 | LIM domain 7 | -0.0842153 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0830779 |
| RIGI | RNA sensor RIG-I | -0.0818404 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0778208 |
| AHNAK | AHNAK nucleoprotein | -0.0760193 |
| PTMA | prothymosin, alpha | -0.0744599 |
| GOLGB1 | golgin B1 | -0.0727379 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0723675 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0681182 |
| XAF1 | XIAP associated factor 1 | -0.0679051 |
| MAP7 | microtubule-associated protein 7 | -0.0678204 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0670074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0664813 |
| PERP | PERP, TP53 apoptosis effector | -0.0656431 |
| AHI1 | Abelson helper integration site 1 | -0.0638048 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0637641 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.062449 |
| MX1 | MX dynamin-like GTPase 1 | -0.0595491 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0585444 |
| LCN2 | lipocalin 2 | -0.0584202 |
| MX2 | MX dynamin-like GTPase 2 | -0.0574182 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0573839 |
| CALR | calreticulin | -0.0559245 |
| HDLBP | high density lipoprotein binding protein | -0.0549774 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0534841 |
| JUN | jun proto-oncogene | -0.0533493 |
| EPCAM | epithelial cell adhesion molecule | -0.0532362 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0530218 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0519387 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0517609 |
| B2M | beta-2-microglobulin | -0.0498502 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0491717 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0483412 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0482427 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0478357 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0472384 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0470583 |
| PKM | pyruvate kinase, muscle | -0.0463947 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0454069 |
| PLSCR1 | phospholipid scramblase 1 | -0.0450271 |
| NF1 | neurofibromin 1 | -0.0439164 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0436322 |
| RPS6 | ribosomal protein S6 | -0.0431357 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0425509 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0424029 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0421379 |
| SPAG9 | sperm associated antigen 9 | -0.0415381 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0408927 |
| ACTG1 | actin gamma 1 | -0.0408833 |
| RPL35A | ribosomal protein L35a | -0.0408162 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0406816 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0403664 |
| CALU | calumenin | -0.0401812 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0400288 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.039104 |
| PMP22 | peripheral myelin protein 22 | -0.0389933 |
| RBM39 | RNA binding motif protein 39 | -0.0371887 |
| ADAR | adenosine deaminase, RNA-specific | -0.0364052 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0358968 |
| ATP11A | ATPase, class VI, type 11A | -0.0356933 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0354574 |
| SEC24D | SEC24 family member D | -0.0351954 |
| RPL34 | ribosomal protein L34 | -0.0349701 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0345774 |
| ABLIM1 | actin binding LIM protein 1 | -0.0340637 |
| SQSTM1 | sequestosome 1 | -0.0340482 |
| INTS6 | integrator complex subunit 6 | -0.0339632 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0337957 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0337323 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0336731 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0334215 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0332986 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0325909 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0323193 |
| GOLGA3 | golgin A3 | -0.0321581 |
| RPL12 | ribosomal protein L12 | -0.0319929 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.03195 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031307 |
| ACTN4 | actinin, alpha 4 | -0.0312419 |
| NPSR1 | neuropeptide S receptor 1 | -0.0311373 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0310955 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309823 |
| RPL19 | ribosomal protein L19 | -0.0309278 |
| IRF1 | interferon regulatory factor 1 | -0.030837 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0308294 |
