| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101309 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.085883 |
| ZNF292 | zinc finger protein 292 | 0.0736431 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.069324 |
| ANKRD12 | ankyrin repeat domain 12 | 0.065343 |
| RAD51B | RAD51 paralog B | 0.0643066 |
| TMF1 | TATA element modulatory factor 1 | 0.0642813 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0635718 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0625554 |
| PRELID2 | PRELI domain containing 2 | 0.0612305 |
| GOLGA4 | golgin A4 | 0.0608191 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0600273 |
| MKI67 | marker of proliferation Ki-67 | 0.0592257 |
| TXNRD1 | thioredoxin reductase 1 | 0.0557541 |
| HMGB2 | high mobility group box 2 | 0.0541001 |
| RPS3 | ribosomal protein S3 | 0.0530814 |
| DIAPH3 | diaphanous-related formin 3 | 0.0528813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.052307 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.051447 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0513333 |
| PTMA | prothymosin, alpha | 0.0500236 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0497398 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0488977 |
| TENM3 | teneurin transmembrane protein 3 | 0.046682 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0453003 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0443847 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0441872 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0436352 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0424764 |
| SET | SET nuclear proto-oncogene | 0.0420267 |
| RBM26 | RNA binding motif protein 26 | 0.0419128 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0405819 |
| ENO1 | enolase 1, (alpha) | 0.0398584 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0393963 |
| MED13L | mediator complex subunit 13-like | 0.0393295 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0391698 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0390411 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0390293 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0387985 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0375696 |
| CENPF | centromere protein F, 350/400kDa | 0.0373131 |
| RPS12 | ribosomal protein S12 | 0.0373035 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0368249 |
| CDK19 | cyclin-dependent kinase 19 | 0.0364002 |
| KIF5B | kinesin family member 5B | 0.0355147 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0353331 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0352492 |
| NUP58 | nucleoporin 58 | 0.0351151 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0350149 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0350031 |
| OGA | O-GlcNAcase | 0.0349499 |
| YME1L1 | YME1-like 1 ATPase | 0.0347537 |
| RPS2 | ribosomal protein S2 | 0.0346583 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0345194 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0340786 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.033927 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0333604 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0329461 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0326859 |
| SBF2 | SET binding factor 2 | 0.0322139 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0321389 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0318357 |
| SFPQ | splicing factor proline/glutamine-rich | 0.03167 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0316269 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0315287 |
| LDHA | lactate dehydrogenase A | 0.0313946 |
| XPO1 | exportin 1 | 0.0312354 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0308713 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0308496 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0306331 |
| TMEM87A | transmembrane protein 87A | 0.0304792 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0304168 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0300049 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0297693 |
| SON | SON DNA binding protein | 0.0296887 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0293171 |
| YEATS2 | YEATS domain containing 2 | 0.0292958 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0291774 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0290825 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0290764 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0289468 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0286633 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0285908 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.028443 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0283854 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0278444 |
| METTL15 | methyltransferase like 15 | 0.027758 |
| TPM3 | tropomyosin 3 | 0.0277022 |
| TPR | translocated promoter region, nuclear basket protein | 0.0276978 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0273097 |
| RBM25 | RNA binding motif protein 25 | 0.0272975 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.027183 |
| YTHDC1 | YTH domain containing 1 | 0.0271648 |
| CEP152 | centrosomal protein 152kDa | 0.0270663 |
| SETD2 | SET domain containing 2 | 0.0269885 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0269247 |
| CEP350 | centrosomal protein 350kDa | 0.0268818 |
| MT2A | metallothionein 2A | 0.0267749 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0267324 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0263722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.378451 |
| AHNAK | AHNAK nucleoprotein | -0.288001 |
| NDRG1 | N-myc downstream regulated 1 | -0.122904 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0882397 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0851711 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0701034 |
| INTS6 | integrator complex subunit 6 | -0.0667852 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0654061 |
| RPL35A | ribosomal protein L35a | -0.0639527 |
| CANX | calnexin | -0.0596837 |
| UBC | ubiquitin C | -0.059469 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0523374 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0499745 |
| VCL | vinculin | -0.0467222 |
| ACTG1 | actin gamma 1 | -0.0460651 |
| S100A10 | S100 calcium binding protein A10 | -0.0451969 |
| CTBP2 | C-terminal binding protein 2 | -0.0440115 |
| FUS | FUS RNA binding protein | -0.043185 |
| PGK1 | phosphoglycerate kinase 1 | -0.0429234 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.042843 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0427684 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0414932 |
| LRRC23 | leucine rich repeat containing 23 | -0.039177 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0363616 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0359597 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0350998 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0338301 |
| ARF1 | ADP-ribosylation factor 1 | -0.0336734 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0334779 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331997 |
| SDC4 | syndecan 4 | -0.0314146 |
| SERINC5 | serine incorporator 5 | -0.0305275 |
| HDLBP | high density lipoprotein binding protein | -0.0304562 |
| PKM | pyruvate kinase, muscle | -0.0304393 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0303743 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0303322 |
| DSG2 | desmoglein 2 | -0.0302816 |
| RPS15 | ribosomal protein S15 | -0.0291958 |
| SQSTM1 | sequestosome 1 | -0.0287693 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0287461 |
| FOXO3 | forkhead box O3 | -0.0286602 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0285266 |
| RPL8 | ribosomal protein L8 | -0.0283367 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0282191 |
| H1-0 | H1.0 linker histone | -0.0270939 |
| RPL4 | ribosomal protein L4 | -0.0257973 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0254111 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0252689 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0251952 |
| UBB | ubiquitin B | -0.0250464 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.024548 |
| MCL1 | myeloid cell leukemia 1 | -0.0245113 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0244904 |
| JUN | jun proto-oncogene | -0.0244786 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0243684 |
| CCNI | cyclin I | -0.024057 |
| CCND1 | cyclin D1 | -0.0239401 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0234639 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0233024 |
| CADPS | Ca++-dependent secretion activator | -0.0231602 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0228519 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0228414 |
| RPL34 | ribosomal protein L34 | -0.0227062 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0226711 |
| HOMER1 | homer scaffolding protein 1 | -0.0223423 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0222729 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0221215 |
| PFKP | phosphofructokinase, platelet | -0.0220202 |
| RCC1 | regulator of chromosome condensation 1 | -0.0220184 |
| VEGFA | vascular endothelial growth factor A | -0.0214277 |
| ADD1 | adducin 1 (alpha) | -0.0213545 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0213488 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0212951 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0212236 |
| S100A6 | S100 calcium binding protein A6 | -0.02118 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0208668 |
| SH3BP2 | SH3-domain binding protein 2 | -0.0206964 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0205805 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0202245 |
| GTF2B | general transcription factor IIB | -0.0201979 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | -0.0196856 |
| TGFB1 | transforming growth factor, beta 1 | -0.0196698 |
| MYO1E | myosin IE | -0.0195733 |
| ATF4 | activating transcription factor 4 | -0.0194707 |
| RPS11 | ribosomal protein S11 | -0.0194044 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0192893 |
| HLA-E | major histocompatibility complex, class I, E | -0.0192301 |
| NABP1 | nucleic acid binding protein 1 | -0.0191857 |
| SLC38A1 | solute carrier family 38, member 1 | -0.018813 |
| EPCAM | epithelial cell adhesion molecule | -0.0183488 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0182689 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0180315 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0180252 |
| PALD1 | phosphatase domain containing, paladin 1 | -0.0177803 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0174968 |
| TAOK1 | TAO kinase 1 | -0.0174749 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0174091 |
| EZR | ezrin | -0.0173385 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0173092 |
| ARF4 | ADP-ribosylation factor 4 | -0.0172886 |
