| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.126073 |
| PRELID2 | PRELI domain containing 2 | 0.0963366 |
| ENO1 | enolase 1, (alpha) | 0.0744365 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0684877 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0550506 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0532151 |
| FLNA | filamin A, alpha | 0.0484535 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0439634 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0372348 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0340647 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0336035 |
| RPS12 | ribosomal protein S12 | 0.0301601 |
| PAX8 | paired box 8 | 0.029266 |
| ITGB8 | integrin, beta 8 | 0.028843 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 0.0284651 |
| CLDN4 | claudin 4 | 0.0283732 |
| LDHA | lactate dehydrogenase A | 0.0280985 |
| RPS3 | ribosomal protein S3 | 0.0279942 |
| RPL21 | ribosomal protein L21 | 0.0273553 |
| FOSL1 | FOS-like antigen 1 | 0.0272928 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0270087 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0251439 |
| RPL18 | ribosomal protein L18 | 0.0248979 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0247391 |
| SLTM | SAFB-like, transcription modulator | 0.0243389 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0233914 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0233315 |
| FHIT | fragile histidine triad | 0.0220529 |
| EGR1 | early growth response 1 | 0.0217744 |
| VIM | vimentin | 0.0217325 |
| RPS7 | ribosomal protein S7 | 0.0215192 |
| RPS17 | ribosomal protein S17 | 0.0210749 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0203271 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.019958 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0196883 |
| ANGPTL4 | angiopoietin-like 4 | 0.019661 |
| MACROD2 | MACRO domain containing 2 | 0.0195806 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0194304 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0192918 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0191645 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190262 |
| ANXA3 | annexin A3 | 0.018971 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0188385 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0187283 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0187272 |
| NUP58 | nucleoporin 58 | 0.0185399 |
| VCL | vinculin | 0.0183665 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0183455 |
| YEATS2 | YEATS domain containing 2 | 0.0181694 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0180863 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0180147 |
| SMC4 | structural maintenance of chromosomes 4 | 0.017827 |
| CIP2A | cellular inhibitor of PP2A | 0.0177576 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0176566 |
| CDK19 | cyclin-dependent kinase 19 | 0.0171161 |
| HYOU1 | hypoxia up-regulated 1 | 0.0169843 |
| SFXN1 | sideroflexin 1 | 0.0167005 |
| AGRN | agrin | 0.016365 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 0.0161974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0161159 |
| DIAPH3 | diaphanous-related formin 3 | 0.0160264 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0159876 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.0159375 |
| GPX4 | glutathione peroxidase 4 | 0.0157934 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0155916 |
| RAI1 | retinoic acid induced 1 | 0.0155779 |
| TPI1 | triosephosphate isomerase 1 | 0.0155513 |
| VCAN | versican | 0.0150922 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0150838 |
| WWOX | WW domain containing oxidoreductase | 0.0150598 |
| KLF6 | Kruppel-like factor 6 | 0.0149506 |
| LAMA5 | laminin, alpha 5 | 0.0148407 |
| DAPK3 | death-associated protein kinase 3 | 0.0147939 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0147095 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0146675 |
| KIF23 | kinesin family member 23 | 0.0145681 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.014445 |
| RPL35 | ribosomal protein L35 | 0.0144307 |
| RPLP2 | ribosomal protein, large, P2 | 0.0144285 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0144244 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0142998 |
| RAD51B | RAD51 paralog B | 0.0140667 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0139405 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0138702 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0137641 |
| MEAK7 | MTOR associated protein, eak-7 homolog | 0.0136005 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0135475 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.0135302 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0134711 |
| TBC1D5 | TBC1 domain family, member 5 | 0.013435 |
| ITGB4 | integrin, beta 4 | 0.0130958 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0130748 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0130022 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0129568 |
| EFNA5 | ephrin-A5 | 0.0128442 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0128254 |
| RHOF | ras homolog family member F (in filopodia) | 0.0127801 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0127034 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0126772 |
| FANCC | Fanconi anemia, complementation group C | 0.0126411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.352998 |
| ACTG1 | actin gamma 1 | -0.231745 |
| AHNAK | AHNAK nucleoprotein | -0.129748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127482 |
| RPL35A | ribosomal protein L35a | -0.113903 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101704 |
| TMSB4X | thymosin beta 4, X-linked | -0.09722 |
| CCND1 | cyclin D1 | -0.0931256 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0868998 |
| S100A10 | S100 calcium binding protein A10 | -0.0860077 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0839237 |
| KRT7 | keratin 7, type II | -0.0778702 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0776418 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0742117 |
| RPL34 | ribosomal protein L34 | -0.0736182 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0682878 |
| ASPH | aspartate beta-hydroxylase | -0.0654893 |
| DSG2 | desmoglein 2 | -0.0630616 |
| RPS6 | ribosomal protein S6 | -0.061316 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.058831 |
| UBC | ubiquitin C | -0.0573904 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0572424 |
| EMP1 | epithelial membrane protein 1 | -0.0559643 |
| PTMA | prothymosin, alpha | -0.0547317 |
| LAMB3 | laminin, beta 3 | -0.0536793 |
| CANX | calnexin | -0.0530869 |
| ANKRD11 | ankyrin repeat domain 11 | -0.053075 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0516776 |
| RPL8 | ribosomal protein L8 | -0.0495261 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0491877 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0484361 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0480112 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0476084 |
| MAP4 | microtubule-associated protein 4 | -0.0473909 |
| DEK | DEK proto-oncogene | -0.0473278 |
| H1-0 | H1.0 linker histone | -0.0467847 |
| RPL32 | ribosomal protein L32 | -0.0464709 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0449588 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0441191 |
| APP | amyloid beta (A4) precursor protein | -0.0435995 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0434943 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0432229 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0422341 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0420974 |
| FUS | FUS RNA binding protein | -0.0414385 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0410586 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.041042 |
| CD2AP | CD2-associated protein | -0.0410107 |
| LAMA4 | laminin, alpha 4 | -0.0403371 |
| SMAD3 | SMAD family member 3 | -0.0402421 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0401274 |
| GOLGA4 | golgin A4 | -0.0395531 |
| SEPTIN7 | septin 7 | -0.0393767 |
| RPS19 | ribosomal protein S19 | -0.0393152 |
| CD44 | CD44 molecule (Indian blood group) | -0.0391096 |
| PGK1 | phosphoglycerate kinase 1 | -0.0389961 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0385516 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0380969 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0376062 |
| ANXA2 | annexin A2 | -0.0374741 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0373469 |
| PLCB4 | phospholipase C, beta 4 | -0.037092 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0366554 |
| WWC1 | WW and C2 domain containing 1 | -0.0366044 |
| CLINT1 | clathrin interactor 1 | -0.0362039 |
| TXNRD1 | thioredoxin reductase 1 | -0.0359926 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359372 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0357889 |
| GOLGB1 | golgin B1 | -0.0351756 |
| FBXO11 | F-box protein 11 | -0.0350042 |
| ACTN4 | actinin, alpha 4 | -0.0349615 |
| RBM39 | RNA binding motif protein 39 | -0.0346185 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0345491 |
| MED13 | mediator complex subunit 13 | -0.0345059 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.034469 |
| CDK12 | cyclin-dependent kinase 12 | -0.034395 |
| RPL14 | ribosomal protein L14 | -0.0343837 |
| RPL38 | ribosomal protein L38 | -0.0341417 |
| RPS11 | ribosomal protein S11 | -0.0339228 |
| SETD5 | SET domain containing 5 | -0.0338103 |
| RPL4 | ribosomal protein L4 | -0.0334445 |
| RTN3 | reticulon 3 | -0.033207 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0327699 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0327326 |
| RPS15 | ribosomal protein S15 | -0.0322274 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0318571 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.031789 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0316312 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0313137 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0310982 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0310018 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0309776 |
| NOP58 | NOP58 ribonucleoprotein | -0.0308673 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0308216 |
| GNAS | GNAS complex locus | -0.0301338 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0294969 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0293975 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0292879 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0292474 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0291116 |
