| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.124863 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.122466 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0967955 |
| TMSB10 | thymosin beta 10 | 0.089231 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0719271 |
| FAM13A | family with sequence similarity 13, member A | 0.0715042 |
| PTMA | prothymosin, alpha | 0.0538356 |
| NGLY1 | N-glycanase 1 | 0.0517691 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0493931 |
| LDHA | lactate dehydrogenase A | 0.0490634 |
| FLNB | filamin B, beta | 0.048363 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0460112 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.045744 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0428879 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.039562 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.038636 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0375762 |
| RUNX1 | runt-related transcription factor 1 | 0.0364928 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0352931 |
| ZNF292 | zinc finger protein 292 | 0.0346115 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0346044 |
| FTL | ferritin, light polypeptide | 0.0336805 |
| RNF24 | ring finger protein 24 | 0.0324549 |
| SEPTIN9 | septin 9 | 0.0319323 |
| ENO1 | enolase 1, (alpha) | 0.0315305 |
| AXL | AXL receptor tyrosine kinase | 0.0300079 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0295661 |
| DUSP6 | dual specificity phosphatase 6 | 0.0295289 |
| DNMBP | dynamin binding protein | 0.0294716 |
| TXNIP | thioredoxin interacting protein | 0.0291686 |
| PDE10A | phosphodiesterase 10A | 0.0290774 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.028175 |
| ARRDC3 | arrestin domain containing 3 | 0.0266894 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0264575 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0261238 |
| MEF2A | myocyte enhancer factor 2A | 0.0252542 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0251105 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0250466 |
| RASA3 | RAS p21 protein activator 3 | 0.0246075 |
| YEATS2 | YEATS domain containing 2 | 0.0244974 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240901 |
| RNF220 | ring finger protein 220 | 0.0236586 |
| LOX | lysyl oxidase | 0.0234182 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0232393 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0229764 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0227222 |
| IRS2 | insulin receptor substrate 2 | 0.0226225 |
| FNDC3B | fibronectin type III domain containing 3B | 0.022613 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0225844 |
| RTN4 | reticulon 4 | 0.0217549 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0216922 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0216273 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0209162 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0209066 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.020486 |
| SBF2 | SET binding factor 2 | 0.0203769 |
| RNF149 | ring finger protein 149 | 0.0201466 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0200581 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0200034 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.019954 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0197894 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0196817 |
| TMEM51 | transmembrane protein 51 | 0.0195193 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0193524 |
| SYNJ2 | synaptojanin 2 | 0.0192927 |
| SP3 | Sp3 transcription factor | 0.0191233 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0190119 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0189951 |
| MKI67 | marker of proliferation Ki-67 | 0.0186418 |
| WDR26 | WD repeat domain 26 | 0.0186081 |
| CD109 | CD109 molecule | 0.0186076 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.018592 |
| LOXL2 | lysyl oxidase-like 2 | 0.0184792 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0183643 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0183191 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0182604 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0182313 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0176144 |
| SMAD3 | SMAD family member 3 | 0.0172272 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0169491 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0167037 |
| CDK19 | cyclin-dependent kinase 19 | 0.0166379 |
| SYAP1 | synapse associated protein 1 | 0.0164914 |
| CENPF | centromere protein F, 350/400kDa | 0.0163643 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0162626 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0162436 |
| RPS3 | ribosomal protein S3 | 0.0162414 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0162169 |
| EFNA5 | ephrin-A5 | 0.0162121 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.016105 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0160316 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0159576 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0158978 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0156103 |
| ARFGEF3 | ARFGEF family member 3 | 0.015546 |
| KLF6 | Kruppel-like factor 6 | 0.0155061 |
| HJURP | Holliday junction recognition protein | 0.0154846 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0152437 |
| ANGPTL4 | angiopoietin-like 4 | 0.0152322 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0149978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.175164 |
| COL5A1 | collagen, type V, alpha 1 | -0.151741 |
| ASPH | aspartate beta-hydroxylase | -0.140635 |
| EXT1 | exostosin glycosyltransferase 1 | -0.134328 |
| ACTG1 | actin gamma 1 | -0.129917 |
| CDH13 | cadherin 13 | -0.124903 |
| HMGA2 | high mobility group AT-hook 2 | -0.118049 |
| VIM | vimentin | -0.108689 |
| NAV1 | neuron navigator 1 | -0.0988342 |
| CD44 | CD44 molecule (Indian blood group) | -0.0987691 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0923972 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0829997 |
| RAI14 | retinoic acid induced 14 | -0.0713909 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0685054 |
| MYO10 | myosin X | -0.0628497 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0595005 |
| AHNAK | AHNAK nucleoprotein | -0.0588647 |
| IGF2 | insulin-like growth factor 2 | -0.0550795 |
| VCL | vinculin | -0.0536133 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0533889 |
| INHBA | inhibin, beta A | -0.051873 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0499025 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0496736 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0486163 |
| CCND1 | cyclin D1 | -0.0471033 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0466186 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0464068 |
| COL1A1 | collagen, type I, alpha 1 | -0.0451377 |
| FRMD4A | FERM domain containing 4A | -0.0421825 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0413403 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0408321 |
| PTK2 | protein tyrosine kinase 2 | -0.040109 |
| EGR1 | early growth response 1 | -0.0399455 |
| INTS6 | integrator complex subunit 6 | -0.0395335 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0395251 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.038779 |
| NABP1 | nucleic acid binding protein 1 | -0.0383836 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0377079 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0376586 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0371984 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0360418 |
| FMN1 | formin 1 | -0.0360183 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0357817 |
| EMP1 | epithelial membrane protein 1 | -0.035768 |
| AFF3 | AF4/FMR2 family, member 3 | -0.035268 |
| EGFR | epidermal growth factor receptor | -0.0344282 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.034002 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0335739 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0335467 |
| TPM1 | tropomyosin 1 (alpha) | -0.0319756 |
| PDLIM5 | PDZ and LIM domain 5 | -0.03163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0316033 |
| PRSS23 | protease, serine, 23 | -0.0313523 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.031179 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0305738 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0304945 |
| RCOR1 | REST corepressor 1 | -0.0304318 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.030388 |
| CLMP | CXADR-like membrane protein | -0.0302707 |
| ANXA2 | annexin A2 | -0.0302645 |
| KIAA1549L | KIAA1549-like | -0.030187 |
| GLIS3 | GLIS family zinc finger 3 | -0.0299602 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0294738 |
| RRBP1 | ribosome binding protein 1 | -0.0293834 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0292577 |
| IL11 | interleukin 11 | -0.0291296 |
| SHISA5 | shisa family member 5 | -0.0289955 |
| CDK6 | cyclin-dependent kinase 6 | -0.0287142 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282578 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0281401 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0280278 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0278777 |
| S100A10 | S100 calcium binding protein A10 | -0.0278039 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0276873 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0276662 |
| AEBP2 | AE binding protein 2 | -0.0275713 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.027565 |
| UBC | ubiquitin C | -0.0274641 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0273447 |
| ATXN1 | ataxin 1 | -0.0272952 |
| GOLGB1 | golgin B1 | -0.0272838 |
| DIAPH2 | diaphanous-related formin 2 | -0.027038 |
| CALU | calumenin | -0.026952 |
| RPL35A | ribosomal protein L35a | -0.0264234 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0264167 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0263688 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0262518 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026018 |
| RND3 | Rho family GTPase 3 | -0.0255357 |
| CCDC138 | coiled-coil domain containing 138 | -0.0255339 |
| CUX1 | cut-like homeobox 1 | -0.0255075 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0253117 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0252483 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0249138 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0243834 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0241883 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0238738 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0237115 |
| POTEF | POTE ankyrin domain family, member F | -0.0235122 |
| ATG7 | autophagy related 7 | -0.0234833 |
