| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.124491 |
| NDRG1 | N-myc downstream regulated 1 | 0.107981 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0906906 |
| PDE10A | phosphodiesterase 10A | 0.0576526 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0514178 |
| FNDC3B | fibronectin type III domain containing 3B | 0.051106 |
| NAV2 | neuron navigator 2 | 0.0483196 |
| VEGFA | vascular endothelial growth factor A | 0.0475711 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0433784 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0431252 |
| MTSS1 | metastasis suppressor 1 | 0.0421519 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0410797 |
| ENO1 | enolase 1, (alpha) | 0.0395028 |
| RUNX1 | runt-related transcription factor 1 | 0.0390787 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0386633 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0369032 |
| CD44 | CD44 molecule (Indian blood group) | 0.0362602 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0344806 |
| HYOU1 | hypoxia up-regulated 1 | 0.033745 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.03334 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0329878 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0321561 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0321207 |
| NAV1 | neuron navigator 1 | 0.029235 |
| LDHA | lactate dehydrogenase A | 0.0289048 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0287057 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0284281 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.027398 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0270648 |
| SMAD3 | SMAD family member 3 | 0.0268425 |
| EGFR | epidermal growth factor receptor | 0.0264597 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0261813 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.026064 |
| ANGPTL4 | angiopoietin-like 4 | 0.0254213 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0246337 |
| LOXL2 | lysyl oxidase-like 2 | 0.0244958 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0243917 |
| WWOX | WW domain containing oxidoreductase | 0.0238204 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.023633 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.02342 |
| HAS2 | hyaluronan synthase 2 | 0.0227656 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227026 |
| PRELID2 | PRELI domain containing 2 | 0.022461 |
| ANO6 | anoctamin 6 | 0.0223382 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0222346 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0218429 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0214979 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0213438 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0212747 |
| TBC1D10A | TBC1 domain family, member 10A | 0.0207971 |
| EFNA5 | ephrin-A5 | 0.0207582 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0197158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194335 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0193172 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.01928 |
| ARRDC3 | arrestin domain containing 3 | 0.0192643 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0191463 |
| RPS12 | ribosomal protein S12 | 0.0187202 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0182984 |
| NOTCH2 | notch 2 | 0.018053 |
| FTL | ferritin, light polypeptide | 0.0179659 |
| APP | amyloid beta (A4) precursor protein | 0.017875 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0178384 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0178172 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0175261 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0175238 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0173445 |
| RPL36 | ribosomal protein L36 | 0.0170284 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0169279 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0168594 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0167796 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0165238 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0164567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0164523 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0162987 |
| TNS1 | tensin 1 | 0.0154711 |
| BMP1 | bone morphogenetic protein 1 | 0.0153973 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0150249 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0150043 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0148662 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0147282 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.014668 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0143385 |
| COL6A2 | collagen, type VI, alpha 2 | 0.014108 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0140004 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.0138494 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0138264 |
| PGM3 | phosphoglucomutase 3 | 0.013823 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0137828 |
| CABIN1 | calcineurin binding protein 1 | 0.0137617 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0136484 |
| CHMP5 | charged multivesicular body protein 5 | 0.0136226 |
| FLNA | filamin A, alpha | 0.0135942 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0135295 |
| PRKCE | protein kinase C, epsilon | 0.0134719 |
| KALRN | kalirin, RhoGEF kinase | 0.0133416 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0132766 |
| VMP1 | vacuole membrane protein 1 | 0.0130832 |
| FAM13A | family with sequence similarity 13, member A | 0.0130642 |
| RPS17 | ribosomal protein S17 | 0.0130205 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.425645 |
| COL1A1 | collagen, type I, alpha 1 | -0.308654 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153342 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.150272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133385 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.102642 |
| VIM | vimentin | -0.09521 |
| FBN1 | fibrillin 1 | -0.0847573 |
| ACTG1 | actin gamma 1 | -0.0777916 |
| COL1A2 | collagen, type I, alpha 2 | -0.0773099 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0768057 |
| CANX | calnexin | -0.0767664 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0702479 |
| TPM4 | tropomyosin 4 | -0.0685218 |
| TMSB4X | thymosin beta 4, X-linked | -0.0626255 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0602192 |
| CALD1 | caldesmon 1 | -0.0586248 |
| MAP1B | microtubule-associated protein 1B | -0.0560835 |
| EXT1 | exostosin glycosyltransferase 1 | -0.05491 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0538023 |
| RPL35A | ribosomal protein L35a | -0.0497212 |
| FN1 | fibronectin 1 | -0.0492751 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0478498 |
| UBC | ubiquitin C | -0.0475419 |
| AHNAK | AHNAK nucleoprotein | -0.0473081 |
| CALU | calumenin | -0.0468975 |
| RRBP1 | ribosome binding protein 1 | -0.0440451 |
| RPS6 | ribosomal protein S6 | -0.0421138 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0407566 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0407198 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0396513 |
| CADM1 | cell adhesion molecule 1 | -0.0390731 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0389757 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0386783 |
| IER3 | immediate early response 3 | -0.0371255 |
| HMGA2 | high mobility group AT-hook 2 | -0.0371116 |
| RAB2A | RAB2A, member RAS oncogene family | -0.036922 |
| QKI | QKI, KH domain containing, RNA binding | -0.0366328 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0359222 |
| DSTN | destrin (actin depolymerizing factor) | -0.0356612 |
| CDH13 | cadherin 13 | -0.0351879 |
| DST | dystonin | -0.0349277 |
| MAP4 | microtubule-associated protein 4 | -0.0334013 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.032035 |
| YBX1 | Y box binding protein 1 | -0.0312749 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0312376 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0309283 |
| PALLD | palladin, cytoskeletal associated protein | -0.0308403 |
| CAVIN1 | caveolae associated protein 1 | -0.0305149 |
| WASF2 | WAS protein family, member 2 | -0.030348 |
| HMCN1 | hemicentin 1 | -0.030278 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0298209 |
| RBM39 | RNA binding motif protein 39 | -0.0296246 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0295772 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0294122 |
| TPM2 | tropomyosin 2 (beta) | -0.0289602 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0287121 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0283924 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0283242 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0276242 |
| POTEF | POTE ankyrin domain family, member F | -0.0275719 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0274792 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0272559 |
| GOLGB1 | golgin B1 | -0.0271046 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0267341 |
| RPL8 | ribosomal protein L8 | -0.0267329 |
| CCND1 | cyclin D1 | -0.0264494 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0263451 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0263357 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0262275 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0261753 |
| HDLBP | high density lipoprotein binding protein | -0.0260174 |
| FSTL1 | follistatin-like 1 | -0.0259528 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0259027 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0258147 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0256852 |
| GLG1 | golgi glycoprotein 1 | -0.0255758 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0254814 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0253444 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0251861 |
| TRAM1 | translocation associated membrane protein 1 | -0.0250627 |
| INHBA | inhibin, beta A | -0.0250205 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0247927 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0247476 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0246667 |
| MT1X | metallothionein 1X | -0.0246231 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0245741 |
| TPM1 | tropomyosin 1 (alpha) | -0.024442 |
| IL6ST | interleukin 6 signal transducer | -0.0243115 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0242955 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0242307 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0241412 |
| FOXP1 | forkhead box P1 | -0.0240538 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0240297 |
| IRF1 | interferon regulatory factor 1 | -0.0238671 |
| THY1 | Thy-1 cell surface antigen | -0.0238309 |
| LOX | lysyl oxidase | -0.0238027 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0237963 |
| GOLGA4 | golgin A4 | -0.0236295 |
| GLIS3 | GLIS family zinc finger 3 | -0.0233915 |
