| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAUR | plasminogen activator, urokinase receptor | 0.0815098 |
| VCL | vinculin | 0.0739217 |
| RPL21 | ribosomal protein L21 | 0.0686087 |
| RPS12 | ribosomal protein S12 | 0.0684299 |
| MCL1 | myeloid cell leukemia 1 | 0.0677024 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.066726 |
| HYOU1 | hypoxia up-regulated 1 | 0.0598253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0590643 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0572409 |
| RPS3 | ribosomal protein S3 | 0.0569929 |
| STK24 | serine/threonine kinase 24 | 0.0530997 |
| ENO1 | enolase 1, (alpha) | 0.0496014 |
| LDHA | lactate dehydrogenase A | 0.0439953 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0436663 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0427383 |
| EGR1 | early growth response 1 | 0.0402981 |
| RAD51B | RAD51 paralog B | 0.0386136 |
| MSN | moesin | 0.0379549 |
| FOSL1 | FOS-like antigen 1 | 0.0365406 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0364017 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0357472 |
| NDRG1 | N-myc downstream regulated 1 | 0.0356578 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.035597 |
| ASPH | aspartate beta-hydroxylase | 0.0349162 |
| MKI67 | marker of proliferation Ki-67 | 0.0330744 |
| VIM | vimentin | 0.0324857 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0323677 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0304051 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0299653 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0297019 |
| RPS17 | ribosomal protein S17 | 0.0295662 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0292544 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0291122 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0287056 |
| RPS7 | ribosomal protein S7 | 0.0277734 |
| TPM3 | tropomyosin 3 | 0.027377 |
| BCL2L1 | BCL2-like 1 | 0.0271696 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0269838 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0266861 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0259301 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0259292 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0258918 |
| JUP | junction plakoglobin | 0.0252918 |
| ABHD2 | abhydrolase domain containing 2 | 0.0249286 |
| RPL9 | ribosomal protein L9 | 0.0249118 |
| IL6ST | interleukin 6 signal transducer | 0.0247635 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0247531 |
| DSPP | dentin sialophosphoprotein | 0.0246688 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0244382 |
| RTN4 | reticulon 4 | 0.0234892 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0233986 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0233459 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0227287 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0223574 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0222775 |
| WDR26 | WD repeat domain 26 | 0.0219006 |
| EHD4 | EH-domain containing 4 | 0.0216538 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0211661 |
| TPM4 | tropomyosin 4 | 0.0211331 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0209302 |
| LATS2 | large tumor suppressor kinase 2 | 0.0208641 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0207372 |
| RIOK3 | RIO kinase 3 | 0.0207134 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0206956 |
| CLDN4 | claudin 4 | 0.0205903 |
| FLNA | filamin A, alpha | 0.0205412 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0204436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203774 |
| CDK19 | cyclin-dependent kinase 19 | 0.0203525 |
| VEGFA | vascular endothelial growth factor A | 0.0202874 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0201715 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0201509 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.020124 |
| RPLP2 | ribosomal protein, large, P2 | 0.0201006 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0200313 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.020028 |
| SEPTIN9 | septin 9 | 0.0197965 |
| PCBP2 | poly(rC) binding protein 2 | 0.0195913 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0194504 |
| PLK2 | polo-like kinase 2 | 0.0193104 |
| HMGB2 | high mobility group box 2 | 0.0192143 |
| RPL37A | ribosomal protein L37a | 0.0191723 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0190654 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.019043 |
| SMAP1 | small ArfGAP 1 | 0.0187883 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0187558 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0187312 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0186615 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0184752 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.018264 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.018223 |
| TNS4 | tensin 4 | 0.0181857 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0181605 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0181532 |
| CHKA | choline kinase alpha | 0.0181256 |
| UBE3A | ubiquitin protein ligase E3A | 0.018108 |
| SMYD3 | SET and MYND domain containing 3 | 0.0179161 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.017871 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0177118 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0176348 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217503 |
| AHNAK | AHNAK nucleoprotein | -0.130802 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123266 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0929991 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0928737 |
| KRT8 | keratin 8, type II | -0.0903862 |
| LYZ | lysozyme | -0.0900028 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0888576 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0884356 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0874958 |
| KRT20 | keratin 20, type I | -0.0791641 |
| CD2AP | CD2-associated protein | -0.0778489 |
| ACTG1 | actin gamma 1 | -0.0773391 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0747209 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0737537 |
| RTN3 | reticulon 3 | -0.0723185 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0715134 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0648942 |
| RPLP1 | ribosomal protein, large, P1 | -0.0606757 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0606333 |
| S100A10 | S100 calcium binding protein A10 | -0.0597124 |
| RPS19 | ribosomal protein S19 | -0.0595715 |
| RPL35A | ribosomal protein L35a | -0.0586859 |
| PTMA | prothymosin, alpha | -0.0586338 |
| RPS21 | ribosomal protein S21 | -0.0584301 |
| RRBP1 | ribosome binding protein 1 | -0.0577921 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0565476 |
| UBC | ubiquitin C | -0.056446 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0563385 |
| NF1 | neurofibromin 1 | -0.0559669 |
| EXPH5 | exophilin 5 | -0.0550293 |
| ASTN2 | astrotactin 2 | -0.0534694 |
| CANX | calnexin | -0.0524217 |
| RPL8 | ribosomal protein L8 | -0.0516248 |
| RPL34 | ribosomal protein L34 | -0.0512285 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0512278 |
| RPS5 | ribosomal protein S5 | -0.051224 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0492552 |
| AGR2 | anterior gradient 2 | -0.0487592 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0484733 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0480312 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0469974 |
| TMEM65 | transmembrane protein 65 | -0.0467322 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0463383 |
| KRT18 | keratin 18, type I | -0.045933 |
| S100A6 | S100 calcium binding protein A6 | -0.0448889 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0438924 |
| RBM39 | RNA binding motif protein 39 | -0.0437243 |
| USP3 | ubiquitin specific peptidase 3 | -0.0432479 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0428735 |
| ARF1 | ADP-ribosylation factor 1 | -0.0423998 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0419683 |
| H1-0 | H1.0 linker histone | -0.0415862 |
| SMAD3 | SMAD family member 3 | -0.0414842 |
| RPS6 | ribosomal protein S6 | -0.0412865 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0409501 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0399071 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0397014 |
| RPS11 | ribosomal protein S11 | -0.0395067 |
| TJP1 | tight junction protein 1 | -0.0389045 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.038733 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.037546 |
| TMEM123 | transmembrane protein 123 | -0.037308 |
| HM13 | histocompatibility (minor) 13 | -0.0368548 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0366196 |
| HDLBP | high density lipoprotein binding protein | -0.036241 |
| ATF3 | activating transcription factor 3 | -0.0357369 |
| RPS23 | ribosomal protein S23 | -0.0355576 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0350537 |
| COG5 | component of oligomeric golgi complex 5 | -0.0347536 |
| POF1B | premature ovarian failure, 1B | -0.0347226 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0345517 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.033639 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0335789 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0334788 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0332093 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0332041 |
| GNAS | GNAS complex locus | -0.0331897 |
| RPLP0 | ribosomal protein, large, P0 | -0.0331547 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0331378 |
| CCNI | cyclin I | -0.0331206 |
| PTK2 | protein tyrosine kinase 2 | -0.0330809 |
| NPR2 | natriuretic peptide receptor 2 | -0.0330252 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0330247 |
| JUN | jun proto-oncogene | -0.0327819 |
| FTL | ferritin, light polypeptide | -0.0325636 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0318705 |
| ECT2 | epithelial cell transforming 2 | -0.0313861 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0312029 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0307812 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.030747 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0305886 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0305078 |
| HMGB1 | high mobility group box 1 | -0.0305074 |
| EPCAM | epithelial cell adhesion molecule | -0.0304751 |
| MMP7 | matrix metallopeptidase 7 | -0.0303349 |
| UBL3 | ubiquitin-like 3 | -0.0300467 |
| RPL4 | ribosomal protein L4 | -0.0298629 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.029705 |
| EMP1 | epithelial membrane protein 1 | -0.0288892 |
