| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.103568 |
| MSN | moesin | 0.0659946 |
| ENO1 | enolase 1, (alpha) | 0.06256 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0620822 |
| FOXO1 | forkhead box O1 | 0.0586111 |
| ITGA6 | integrin, alpha 6 | 0.0573346 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0543489 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0523296 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0486086 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0475594 |
| MT2A | metallothionein 2A | 0.0462927 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.044719 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0445883 |
| FOSL1 | FOS-like antigen 1 | 0.0432922 |
| BCL2L1 | BCL2-like 1 | 0.042925 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0409648 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0407882 |
| PLAT | plasminogen activator, tissue | 0.0398172 |
| RPL21 | ribosomal protein L21 | 0.0386975 |
| ANGPTL4 | angiopoietin-like 4 | 0.0376448 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0368233 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365452 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0360134 |
| PDLIM1 | PDZ and LIM domain 1 | 0.035636 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0350715 |
| ZNF292 | zinc finger protein 292 | 0.0348915 |
| TGM2 | transglutaminase 2 | 0.0344813 |
| LDHA | lactate dehydrogenase A | 0.0337173 |
| ASPH | aspartate beta-hydroxylase | 0.0332795 |
| DOK5 | docking protein 5 | 0.0329742 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0323266 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0308173 |
| B2M | beta-2-microglobulin | 0.0307907 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0307901 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.030501 |
| RIN2 | Ras and Rab interactor 2 | 0.0303106 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0300371 |
| PRELID2 | PRELI domain containing 2 | 0.0299951 |
| LAMA5 | laminin, alpha 5 | 0.0298375 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0297832 |
| TPM3 | tropomyosin 3 | 0.0296266 |
| TNS4 | tensin 4 | 0.0295172 |
| LUZP1 | leucine zipper protein 1 | 0.0294272 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0291967 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0285648 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0285263 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0284824 |
| RPS12 | ribosomal protein S12 | 0.0283224 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0278851 |
| MYO10 | myosin X | 0.027233 |
| SMYD3 | SET and MYND domain containing 3 | 0.0268658 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0261054 |
| PCDH1 | protocadherin 1 | 0.0257733 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0252457 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0252128 |
| MYOF | myoferlin | 0.0251947 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0249327 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0248742 |
| JAG1 | jagged 1 | 0.024669 |
| LIMA1 | LIM domain and actin binding 1 | 0.0245744 |
| CLU | clusterin | 0.0244503 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0243054 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0239793 |
| MTSS1 | metastasis suppressor 1 | 0.0235609 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0235608 |
| FAM13A | family with sequence similarity 13, member A | 0.023516 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023482 |
| RNF220 | ring finger protein 220 | 0.0233993 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0230016 |
| CENPF | centromere protein F, 350/400kDa | 0.0227166 |
| KIAA0040 | KIAA0040 | 0.0218093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0216439 |
| SLTM | SAFB-like, transcription modulator | 0.0215421 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0213511 |
| SLK | STE20-like kinase | 0.0210812 |
| CAPRIN2 | caprin family member 2 | 0.0210715 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0209991 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0204589 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0204137 |
| IFI44 | interferon-induced protein 44 | 0.020312 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0202806 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0200932 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0199163 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0196053 |
| RAD51B | RAD51 paralog B | 0.019324 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190518 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.018946 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0188621 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0181112 |
| C4BPB | complement component 4 binding protein, beta | 0.0179726 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0179221 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.017845 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0177492 |
| PLS3 | plastin 3 | 0.0177386 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0175138 |
| PRKCH | protein kinase C, eta | 0.0173944 |
| C1D | C1D nuclear receptor corepressor | 0.0172064 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0170155 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0169689 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0169217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.187741 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.187037 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172152 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165893 |
| TMSB4X | thymosin beta 4, X-linked | -0.121422 |
| AHNAK | AHNAK nucleoprotein | -0.114796 |
| S100A10 | S100 calcium binding protein A10 | -0.113767 |
| PTMA | prothymosin, alpha | -0.10847 |
| EMP1 | epithelial membrane protein 1 | -0.103142 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0963738 |
| RBM39 | RNA binding motif protein 39 | -0.0900034 |
| FLNB | filamin B, beta | -0.0889145 |
| RPS21 | ribosomal protein S21 | -0.0776997 |
| LMO7 | LIM domain 7 | -0.0767845 |
| CANX | calnexin | -0.0760293 |
| GNAS | GNAS complex locus | -0.0708577 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0695516 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.068832 |
| IGF2 | insulin-like growth factor 2 | -0.0647416 |
| ANXA1 | annexin A1 | -0.0638189 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0611261 |
| RPL8 | ribosomal protein L8 | -0.0607232 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0577883 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0575583 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0554822 |
| LMNA | lamin A/C | -0.0550498 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0543207 |
| TMSB10 | thymosin beta 10 | -0.0543186 |
| H1-0 | H1.0 linker histone | -0.0543178 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0537958 |
| WASF2 | WAS protein family, member 2 | -0.0537497 |
| UBC | ubiquitin C | -0.0519011 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.049697 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0495455 |
| HLA-E | major histocompatibility complex, class I, E | -0.0492935 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0477893 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0477738 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0475419 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0474885 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0474239 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0458602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0455847 |
| RPS24 | ribosomal protein S24 | -0.0455777 |
| KRT17 | keratin 17, type I | -0.0455298 |
| RAI14 | retinoic acid induced 14 | -0.045404 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0450141 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0449742 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0437686 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0430515 |
| SQLE | squalene epoxidase | -0.0422383 |
| RPL34 | ribosomal protein L34 | -0.0421188 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0414214 |
| RRBP1 | ribosome binding protein 1 | -0.0412154 |
| ANXA2 | annexin A2 | -0.0410559 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.040746 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0402587 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0401054 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0393556 |
| HLA-B | major histocompatibility complex, class I, B | -0.0392669 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0391551 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0389732 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0386574 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385891 |
| NAV2 | neuron navigator 2 | -0.0384927 |
| RPS6 | ribosomal protein S6 | -0.0383965 |
| ACTG1 | actin gamma 1 | -0.0383085 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0382619 |
| MORF4L2 | mortality factor 4 like 2 | -0.0380165 |
| RPL35A | ribosomal protein L35a | -0.0379601 |
| ARF1 | ADP-ribosylation factor 1 | -0.0378624 |
| INTS6 | integrator complex subunit 6 | -0.0377 |
| THBD | thrombomodulin | -0.0375474 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0374019 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0373022 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0370953 |
| STC1 | stanniocalcin 1 | -0.0367707 |
| HM13 | histocompatibility (minor) 13 | -0.0366625 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0363914 |
| PGK1 | phosphoglycerate kinase 1 | -0.0361793 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0355063 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.035501 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0354856 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0352374 |
| SQSTM1 | sequestosome 1 | -0.0351028 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0347807 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0343073 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0342199 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0338049 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0330879 |
| SDC4 | syndecan 4 | -0.0327509 |
| CLINT1 | clathrin interactor 1 | -0.0326554 |
| CAVIN1 | caveolae associated protein 1 | -0.0320761 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0318872 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0318235 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0317911 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0314596 |
| RPL11 | ribosomal protein L11 | -0.0311182 |
| TKT | transketolase | -0.0311045 |
| CD44 | CD44 molecule (Indian blood group) | -0.0305363 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0304795 |
