| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.182144 |
| FN1 | fibronectin 1 | 0.160955 |
| MT2A | metallothionein 2A | 0.149422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.110468 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0915206 |
| ENO1 | enolase 1, (alpha) | 0.0812947 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0801705 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0793264 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0725872 |
| FLNB | filamin B, beta | 0.0673893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.05958 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0581492 |
| COL5A1 | collagen, type V, alpha 1 | 0.0550835 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0536105 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0497005 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0484781 |
| CD44 | CD44 molecule (Indian blood group) | 0.0482929 |
| DST | dystonin | 0.0475639 |
| TMSB10 | thymosin beta 10 | 0.0454685 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0442253 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0437451 |
| RAD51B | RAD51 paralog B | 0.0435077 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0427656 |
| PODXL | podocalyxin-like | 0.0427533 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0411094 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0402409 |
| NAV1 | neuron navigator 1 | 0.0388579 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0364644 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0363522 |
| SMYD3 | SET and MYND domain containing 3 | 0.0358781 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355233 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0352338 |
| TENM3 | teneurin transmembrane protein 3 | 0.0345952 |
| ERBIN | erbb2 interacting protein | 0.0345791 |
| NAV2 | neuron navigator 2 | 0.0342199 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0333973 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0331161 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0328789 |
| GLIS3 | GLIS family zinc finger 3 | 0.0304734 |
| VIM | vimentin | 0.0300016 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.029164 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0282038 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.02814 |
| EGFR | epidermal growth factor receptor | 0.0280601 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0278035 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0277851 |
| FHIT | fragile histidine triad | 0.0276189 |
| VCL | vinculin | 0.0274087 |
| SBF2 | SET binding factor 2 | 0.0272323 |
| EGR1 | early growth response 1 | 0.0267074 |
| ANXA2 | annexin A2 | 0.0262221 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0259483 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0258628 |
| FLNA | filamin A, alpha | 0.0256701 |
| PLCB4 | phospholipase C, beta 4 | 0.0256499 |
| CUX1 | cut-like homeobox 1 | 0.0253561 |
| MYO1E | myosin IE | 0.0252691 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0251976 |
| PRELID2 | PRELI domain containing 2 | 0.0250193 |
| RAI14 | retinoic acid induced 14 | 0.0248148 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.024786 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.024619 |
| OSMR | oncostatin M receptor | 0.0245779 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0243761 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0241445 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0240332 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0238683 |
| HLA-A | major histocompatibility complex, class I, A | 0.0237563 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0235905 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.023382 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0233055 |
| VEGFC | vascular endothelial growth factor C | 0.0232394 |
| WWOX | WW domain containing oxidoreductase | 0.0230783 |
| MECOM | MDS1 and EVI1 complex locus | 0.0229656 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.022922 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.022608 |
| STC2 | stanniocalcin 2 | 0.0225596 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0224171 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0223431 |
| MYLK | myosin light chain kinase | 0.0222545 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0221784 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.02206 |
| RPS3 | ribosomal protein S3 | 0.0219205 |
| DIAPH3 | diaphanous-related formin 3 | 0.021842 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0217117 |
| LOXL2 | lysyl oxidase-like 2 | 0.0216696 |
| TNS3 | tensin 3 | 0.0215858 |
| SULF1 | sulfatase 1 | 0.0213298 |
| CAVIN1 | caveolae associated protein 1 | 0.0213135 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0213019 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0212731 |
| FOXP1 | forkhead box P1 | 0.0211766 |
| ZNF804A | zinc finger protein 804A | 0.0208756 |
| FER | fer (fps/fes related) tyrosine kinase | 0.020861 |
| PDE10A | phosphodiesterase 10A | 0.0198965 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0198542 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0196667 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0194305 |
| GANAB | glucosidase, alpha; neutral AB | 0.0191323 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0190606 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.321785 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.159865 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148029 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.131577 |
| DEK | DEK proto-oncogene | -0.103131 |
| FTL | ferritin, light polypeptide | -0.0942786 |
| HLA-B | major histocompatibility complex, class I, B | -0.078796 |
| ADM | adrenomedullin | -0.0766265 |
| CANX | calnexin | -0.0739827 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0688831 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0687554 |
| UBC | ubiquitin C | -0.0673272 |
| NDRG1 | N-myc downstream regulated 1 | -0.0670566 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0633454 |
| SPAG9 | sperm associated antigen 9 | -0.0619365 |
| GOLGA4 | golgin A4 | -0.0597788 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0574043 |
| NUP58 | nucleoporin 58 | -0.0483285 |
| POTEF | POTE ankyrin domain family, member F | -0.0465659 |
| B2M | beta-2-microglobulin | -0.0464855 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0461882 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0431085 |
| SQSTM1 | sequestosome 1 | -0.0430647 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0420746 |
| ACTG1 | actin gamma 1 | -0.0402504 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0389275 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388435 |
| S100A10 | S100 calcium binding protein A10 | -0.0384826 |
| RLF | rearranged L-myc fusion | -0.0382075 |
| BRD2 | bromodomain containing 2 | -0.0373179 |
| TPD52 | tumor protein D52 | -0.0370441 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0368811 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0366946 |
| NOP58 | NOP58 ribonucleoprotein | -0.0357981 |
| USP3 | ubiquitin specific peptidase 3 | -0.0357937 |
| TMSB4X | thymosin beta 4, X-linked | -0.0357714 |
| RYBP | RING1 and YY1 binding protein | -0.0352198 |
| QKI | QKI, KH domain containing, RNA binding | -0.0351319 |
| TXNRD1 | thioredoxin reductase 1 | -0.0347182 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0345773 |
| TFG | TRK-fused gene | -0.0342912 |
| CCNL1 | cyclin L1 | -0.0341834 |
| WTAP | Wilms tumor 1 associated protein | -0.0339015 |
| GOLGB1 | golgin B1 | -0.0335855 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.033513 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.033423 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0331297 |
| MT1X | metallothionein 1X | -0.0330714 |
| RPL35A | ribosomal protein L35a | -0.0326829 |
| RPS6 | ribosomal protein S6 | -0.0326618 |
| RIOK3 | RIO kinase 3 | -0.0323122 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0322955 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0319721 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0316441 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0313941 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0310793 |
| H1-4 | H1.4 linker histone, cluster member | -0.0307332 |
| JUN | jun proto-oncogene | -0.0298811 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.029547 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0294827 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0291273 |
| USP12 | ubiquitin specific peptidase 12 | -0.029047 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0289005 |
| RND3 | Rho family GTPase 3 | -0.0288999 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0288899 |
| GOLT1B | golgi transport 1B | -0.0283248 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0282684 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0282675 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0279924 |
| RHEB | Ras homolog enriched in brain | -0.0279314 |
| WDR45B | WD repeat domain 45B | -0.0277136 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.027562 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0272254 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0271848 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0271631 |
| TRAM1 | translocation associated membrane protein 1 | -0.0268739 |
| AHNAK | AHNAK nucleoprotein | -0.0264955 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0261014 |
| TPX2 | TPX2, microtubule-associated | -0.0260935 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0260443 |
| PAPOLA | poly(A) polymerase alpha | -0.0255909 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0255116 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0252062 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025079 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0249061 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0248743 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0248281 |
| GNAS | GNAS complex locus | -0.0246454 |
| INSIG1 | insulin induced gene 1 | -0.0246077 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0245029 |
| YBX1 | Y box binding protein 1 | -0.0244348 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0243129 |
| CALR | calreticulin | -0.0242306 |
| OPTN | optineurin | -0.0240514 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0240372 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.024012 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0239309 |
| BRD4 | bromodomain containing 4 | -0.0239194 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0238124 |
| MLF1 | myeloid leukemia factor 1 | -0.0237892 |
