| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.122731 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.114936 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.107249 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.105216 |
| ENO1 | enolase 1, (alpha) | 0.0865419 |
| RPS12 | ribosomal protein S12 | 0.0816741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0767619 |
| FAM13A | family with sequence similarity 13, member A | 0.0754661 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0751738 |
| LDHA | lactate dehydrogenase A | 0.0740757 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0679802 |
| PRELID2 | PRELI domain containing 2 | 0.0623838 |
| FAT1 | FAT atypical cadherin 1 | 0.0585474 |
| TXNIP | thioredoxin interacting protein | 0.0565972 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0561281 |
| RPS3 | ribosomal protein S3 | 0.0544857 |
| DSPP | dentin sialophosphoprotein | 0.0541695 |
| TNS4 | tensin 4 | 0.0521363 |
| KIF5B | kinesin family member 5B | 0.0492113 |
| ITGA6 | integrin, alpha 6 | 0.0458423 |
| MED13L | mediator complex subunit 13-like | 0.0454007 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0431068 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0429621 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0424623 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0414291 |
| RPS2 | ribosomal protein S2 | 0.0404887 |
| EREG | epiregulin | 0.0395404 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0391451 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0388471 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0375979 |
| FOSL1 | FOS-like antigen 1 | 0.0372432 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0361838 |
| ASPH | aspartate beta-hydroxylase | 0.0357017 |
| RPS7 | ribosomal protein S7 | 0.0352699 |
| RPL37A | ribosomal protein L37a | 0.0348959 |
| FLNB | filamin B, beta | 0.0347808 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0347228 |
| HMGB2 | high mobility group box 2 | 0.0343683 |
| TPM3 | tropomyosin 3 | 0.0341335 |
| PTEN | phosphatase and tensin homolog | 0.0339226 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0334051 |
| DNM2 | dynamin 2 | 0.0327195 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0321172 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0316371 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0313141 |
| ZNF292 | zinc finger protein 292 | 0.0311874 |
| RPS17 | ribosomal protein S17 | 0.0310099 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0306344 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0301438 |
| CENPF | centromere protein F, 350/400kDa | 0.0300197 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0298727 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0294472 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0293151 |
| SLTM | SAFB-like, transcription modulator | 0.0292642 |
| EPHA2 | EPH receptor A2 | 0.0287717 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0287591 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0283215 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267518 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0267165 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.026696 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.02655 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0264758 |
| ABHD17C | abhydrolase domain containing 17C | 0.0262808 |
| KIAA0040 | KIAA0040 | 0.0259956 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0253535 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0252453 |
| ANXA2 | annexin A2 | 0.0251434 |
| ANXA11 | annexin A11 | 0.0251354 |
| LIMA1 | LIM domain and actin binding 1 | 0.0246687 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0245064 |
| RNF43 | ring finger protein 43 | 0.0244473 |
| MCL1 | myeloid cell leukemia 1 | 0.0243671 |
| MINK1 | misshapen-like kinase 1 | 0.0242514 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0241948 |
| CCDC6 | coiled-coil domain containing 6 | 0.0241696 |
| ITGB4 | integrin, beta 4 | 0.024121 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240639 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0239165 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0238533 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0237674 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0236336 |
| CDK19 | cyclin-dependent kinase 19 | 0.0235725 |
| SBF2 | SET binding factor 2 | 0.0234813 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0234002 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0233092 |
| BCL2L1 | BCL2-like 1 | 0.0232161 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0229746 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0226748 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0225763 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0224591 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0223998 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0223885 |
| JAG1 | jagged 1 | 0.0222784 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0222621 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0222261 |
| CDCP1 | CUB domain containing protein 1 | 0.0221968 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0218314 |
| SET | SET nuclear proto-oncogene | 0.0217343 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0217174 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0215918 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.435015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.216205 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150394 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.146922 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.124673 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.120722 |
| ACTG1 | actin gamma 1 | -0.106144 |
| RPL35A | ribosomal protein L35a | -0.104483 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0891053 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0790061 |
| AHNAK | AHNAK nucleoprotein | -0.0788264 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0698429 |
| RPS6 | ribosomal protein S6 | -0.0692787 |
| MYO1E | myosin IE | -0.0679008 |
| PIGR | polymeric immunoglobulin receptor | -0.0633665 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0631378 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0621756 |
| AGR2 | anterior gradient 2 | -0.0590581 |
| RPL34 | ribosomal protein L34 | -0.0589325 |
| UBC | ubiquitin C | -0.0581938 |
| CANX | calnexin | -0.0539231 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0530823 |
| S100A10 | S100 calcium binding protein A10 | -0.0517804 |
| RPL8 | ribosomal protein L8 | -0.0488215 |
| H1-0 | H1.0 linker histone | -0.0467799 |
| RPS19 | ribosomal protein S19 | -0.0460592 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0438465 |
| IER3 | immediate early response 3 | -0.0403168 |
| CCNI | cyclin I | -0.0398433 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0389709 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.038885 |
| RPS23 | ribosomal protein S23 | -0.0382593 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0366648 |
| CCND1 | cyclin D1 | -0.0365555 |
| SLC38A2 | solute carrier family 38, member 2 | -0.036162 |
| DEK | DEK proto-oncogene | -0.0358533 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0355912 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0352637 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0332266 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0328369 |
| ARF1 | ADP-ribosylation factor 1 | -0.0327875 |
| NPSR1 | neuropeptide S receptor 1 | -0.0319229 |
| GDF15 | growth differentiation factor 15 | -0.0318808 |
| RPL32 | ribosomal protein L32 | -0.0310713 |
| ABLIM1 | actin binding LIM protein 1 | -0.0310564 |
| RPS11 | ribosomal protein S11 | -0.0307791 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0300645 |
| RRBP1 | ribosome binding protein 1 | -0.0297793 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0290114 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0285414 |
| RPS21 | ribosomal protein S21 | -0.0277679 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0272782 |
| LMO7 | LIM domain 7 | -0.0271246 |
| RPLP1 | ribosomal protein, large, P1 | -0.0269762 |
| PGK1 | phosphoglycerate kinase 1 | -0.0266333 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0260271 |
| MT1X | metallothionein 1X | -0.0257001 |
| RPS15 | ribosomal protein S15 | -0.0256727 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0254849 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254631 |
| FBXO11 | F-box protein 11 | -0.0254287 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0254116 |
| ATF4 | activating transcription factor 4 | -0.0253898 |
| ASTN2 | astrotactin 2 | -0.0252157 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0250505 |
| HDLBP | high density lipoprotein binding protein | -0.0248992 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0247119 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0240197 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0239655 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0238228 |
| CD44 | CD44 molecule (Indian blood group) | -0.0238067 |
| YBX1 | Y box binding protein 1 | -0.0237896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0237822 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.023676 |
| MED13 | mediator complex subunit 13 | -0.023326 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0231179 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0227678 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0225957 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.022282 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0222203 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0216701 |
| S100A6 | S100 calcium binding protein A6 | -0.0214058 |
| CDK12 | cyclin-dependent kinase 12 | -0.0213584 |
| FTL | ferritin, light polypeptide | -0.0205 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0203969 |
| AHI1 | Abelson helper integration site 1 | -0.0203726 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0200847 |
| RPL38 | ribosomal protein L38 | -0.0200833 |
| POTEF | POTE ankyrin domain family, member F | -0.0199175 |
| SNX9 | sorting nexin 9 | -0.0198261 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0197537 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0197228 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0195709 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0194117 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0193853 |
| ZNF33A | zinc finger protein 33A | -0.019095 |
| RPL6 | ribosomal protein L6 | -0.0189717 |
| TFF3 | trefoil factor 3 (intestinal) | -0.018911 |
| RTN3 | reticulon 3 | -0.0188821 |
| RPLP0 | ribosomal protein, large, P0 | -0.0188114 |
