| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.128139 |
| FAT1 | FAT atypical cadherin 1 | 0.125257 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.101152 |
| PKP2 | plakophilin 2 | 0.0977692 |
| ANXA2 | annexin A2 | 0.0965845 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0956168 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0911361 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0857048 |
| ABHD17C | abhydrolase domain containing 17C | 0.0834316 |
| MYO1E | myosin IE | 0.0800959 |
| PRSS3 | protease, serine, 3 | 0.0760668 |
| ITGA6 | integrin, alpha 6 | 0.0740212 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0680421 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0660811 |
| RPS12 | ribosomal protein S12 | 0.065875 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0642349 |
| LMO7 | LIM domain 7 | 0.0627298 |
| MYOF | myoferlin | 0.0603119 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0579813 |
| WWC1 | WW and C2 domain containing 1 | 0.057166 |
| SERINC5 | serine incorporator 5 | 0.0567151 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.055407 |
| VCL | vinculin | 0.055302 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0549441 |
| TMEM45B | transmembrane protein 45B | 0.0546546 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0536499 |
| RPS3 | ribosomal protein S3 | 0.053045 |
| LAMB3 | laminin, beta 3 | 0.052496 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0490154 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0484675 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0480413 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0478303 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0464279 |
| DSPP | dentin sialophosphoprotein | 0.0464248 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.046396 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0449776 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0447546 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0447538 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0441695 |
| TLN2 | talin 2 | 0.0438089 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0431159 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0426514 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0423587 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0418491 |
| ACTN4 | actinin, alpha 4 | 0.0416901 |
| MUC13 | mucin 13, cell surface associated | 0.0414186 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0411961 |
| SEPTIN10 | septin 10 | 0.0409795 |
| TC2N | tandem C2 domains, nuclear | 0.0409725 |
| RAD51B | RAD51 paralog B | 0.0408804 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0408295 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0396811 |
| ENO1 | enolase 1, (alpha) | 0.0390215 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0379076 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376148 |
| SLTM | SAFB-like, transcription modulator | 0.037402 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0364487 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0359971 |
| ASPH | aspartate beta-hydroxylase | 0.03555 |
| MX1 | MX dynamin-like GTPase 1 | 0.035298 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0352791 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0349956 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0349167 |
| FHL2 | four and a half LIM domains 2 | 0.034813 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0347022 |
| FOXP1 | forkhead box P1 | 0.0343456 |
| FOXO1 | forkhead box O1 | 0.0343005 |
| MSI2 | musashi RNA-binding protein 2 | 0.0342791 |
| PRELID2 | PRELI domain containing 2 | 0.0341914 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0332722 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0331079 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0330303 |
| RPS17 | ribosomal protein S17 | 0.0330246 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0327975 |
| EFNB2 | ephrin-B2 | 0.0326732 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0326013 |
| ETV6 | ets variant 6 | 0.0325779 |
| RPS7 | ribosomal protein S7 | 0.03251 |
| PARD3B | par-3 family cell polarity regulator beta | 0.032199 |
| PYGB | phosphorylase, glycogen; brain | 0.0317879 |
| EZR | ezrin | 0.0315143 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0311505 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0309963 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0309042 |
| ITGB4 | integrin, beta 4 | 0.0301992 |
| LAMA4 | laminin, alpha 4 | 0.0299976 |
| RPL13A | ribosomal protein L13a | 0.0296982 |
| MTAP | methylthioadenosine phosphorylase | 0.0294441 |
| SHROOM3 | shroom family member 3 | 0.0294321 |
| RIGI | RNA sensor RIG-I | 0.0286462 |
| CTBP2 | C-terminal binding protein 2 | 0.0285103 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.028449 |
| TSPAN8 | tetraspanin 8 | 0.0281114 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0279361 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0276865 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0273566 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0272735 |
| BCL2L1 | BCL2-like 1 | 0.0271471 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0270847 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0270308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219559 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.206497 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.151131 |
| RPS6 | ribosomal protein S6 | -0.115471 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0916788 |
| GOLGA4 | golgin A4 | -0.0916663 |
| ACTG1 | actin gamma 1 | -0.0822596 |
| RPS23 | ribosomal protein S23 | -0.0753111 |
| RPL35A | ribosomal protein L35a | -0.075204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0737953 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0639926 |
| PTMA | prothymosin, alpha | -0.0593537 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0573191 |
| RPS19 | ribosomal protein S19 | -0.0562977 |
| RPL8 | ribosomal protein L8 | -0.053676 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0531698 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0528984 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0519188 |
| UBC | ubiquitin C | -0.0503199 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0498547 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.049845 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497822 |
| CCNI | cyclin I | -0.0490333 |
| CANX | calnexin | -0.0489282 |
| CALB1 | calbindin 1, 28kDa | -0.0477794 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.046421 |
| RPL34 | ribosomal protein L34 | -0.0449183 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446163 |
| ARF4 | ADP-ribosylation factor 4 | -0.0415477 |
| YBX1 | Y box binding protein 1 | -0.040868 |
| SETD5 | SET domain containing 5 | -0.0408479 |
| RPS11 | ribosomal protein S11 | -0.0407118 |
| HLA-B | major histocompatibility complex, class I, B | -0.0404265 |
| BRD2 | bromodomain containing 2 | -0.0401449 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0384237 |
| DEK | DEK proto-oncogene | -0.0371803 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0365392 |
| GLG1 | golgi glycoprotein 1 | -0.0361242 |
| RPS13 | ribosomal protein S13 | -0.0354273 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0354131 |
| TMSB10 | thymosin beta 10 | -0.0345222 |
| RPS14 | ribosomal protein S14 | -0.034458 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.034024 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0339827 |
| COPA | coatomer protein complex, subunit alpha | -0.0339322 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0326759 |
| JMY | junction mediating and regulatory protein, p53 cofactor | -0.0324238 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0321351 |
| HMGA1 | high mobility group AT-hook 1 | -0.0318927 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0316753 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316399 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.031215 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0311089 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0310376 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0308618 |
| RPS8 | ribosomal protein S8 | -0.0305648 |
| NKTR | natural killer cell triggering receptor | -0.0302575 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0301802 |
| MORF4L2 | mortality factor 4 like 2 | -0.0301219 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0300272 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.029859 |
| RPS21 | ribosomal protein S21 | -0.029473 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0294489 |
| GDF15 | growth differentiation factor 15 | -0.0289779 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0287747 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0284368 |
| ZNF638 | zinc finger protein 638 | -0.0281912 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0281476 |
| SRP54 | signal recognition particle 54kDa | -0.0278096 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0276979 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0275399 |
| RPL32 | ribosomal protein L32 | -0.0273919 |
| S100A10 | S100 calcium binding protein A10 | -0.0273895 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0272483 |
| POTEF | POTE ankyrin domain family, member F | -0.0272237 |
| ASTN2 | astrotactin 2 | -0.0270583 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0269923 |
| USP3 | ubiquitin specific peptidase 3 | -0.0268921 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0268108 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267423 |
| RPS15 | ribosomal protein S15 | -0.0264937 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0263091 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.026161 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0255712 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.025539 |
| CALU | calumenin | -0.0255246 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0251879 |
| RRBP1 | ribosome binding protein 1 | -0.025045 |
| SEC61G | Sec61 gamma subunit | -0.0248804 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0246378 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.024631 |
| MTDH | metadherin | -0.0245502 |
| SEC24A | SEC24 family member A | -0.0244474 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0238029 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0234446 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0234135 |
| RNF145 | ring finger protein 145 | -0.0232256 |
| RPS5 | ribosomal protein S5 | -0.0230571 |
| COG5 | component of oligomeric golgi complex 5 | -0.0229486 |
| CCNG1 | cyclin G1 | -0.0228277 |
