| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.210775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.074463 |
| TMSB10 | thymosin beta 10 | 0.0630717 |
| ANGPTL4 | angiopoietin-like 4 | 0.0551634 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0493752 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0459292 |
| MT1E | metallothionein 1E | 0.0435777 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0425109 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0415042 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0411775 |
| RPS12 | ribosomal protein S12 | 0.0406744 |
| CAPRIN2 | caprin family member 2 | 0.0391657 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0366392 |
| ENO1 | enolase 1, (alpha) | 0.0365694 |
| EZR | ezrin | 0.0350806 |
| SQSTM1 | sequestosome 1 | 0.0347411 |
| FTL | ferritin, light polypeptide | 0.0343666 |
| RPS3 | ribosomal protein S3 | 0.0330277 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0321967 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0313018 |
| RPL12 | ribosomal protein L12 | 0.0312352 |
| RPL23 | ribosomal protein L23 | 0.0300041 |
| RTTN | rotatin | 0.0293652 |
| WDR26 | WD repeat domain 26 | 0.0293331 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0289141 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.027448 |
| VCL | vinculin | 0.0271736 |
| MKI67 | marker of proliferation Ki-67 | 0.0258489 |
| RTN4 | reticulon 4 | 0.0254607 |
| RPS17 | ribosomal protein S17 | 0.0254579 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0253108 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0250408 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0248971 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0246572 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0241323 |
| FOSL1 | FOS-like antigen 1 | 0.0238766 |
| RACK1 | receptor for activated C kinase 1 | 0.0234303 |
| RPL18 | ribosomal protein L18 | 0.0233412 |
| YBX3 | Y box binding protein 3 | 0.0229682 |
| RAD51B | RAD51 paralog B | 0.0227848 |
| PTMA | prothymosin, alpha | 0.0227258 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0224821 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.022333 |
| RPL36 | ribosomal protein L36 | 0.022135 |
| HPCAL1 | hippocalcin-like 1 | 0.0220353 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0216558 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0213526 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0212545 |
| RPS2 | ribosomal protein S2 | 0.0210747 |
| HMGB2 | high mobility group box 2 | 0.0210521 |
| S100A6 | S100 calcium binding protein A6 | 0.0209459 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208831 |
| RPS7 | ribosomal protein S7 | 0.0204209 |
| RRM2 | ribonucleotide reductase M2 | 0.0203281 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0202486 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0200261 |
| F2R | coagulation factor II (thrombin) receptor | 0.019762 |
| KLF6 | Kruppel-like factor 6 | 0.0195904 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.019518 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0195116 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0192736 |
| USP34 | ubiquitin specific peptidase 34 | 0.0191786 |
| OGA | O-GlcNAcase | 0.0190598 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0189725 |
| PHF21A | PHD finger protein 21A | 0.0189567 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0188009 |
| CENPF | centromere protein F, 350/400kDa | 0.0185886 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0185317 |
| RPLP2 | ribosomal protein, large, P2 | 0.0181993 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0179741 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0178312 |
| RAI1 | retinoic acid induced 1 | 0.0178019 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0176417 |
| PRDX1 | peroxiredoxin 1 | 0.0172668 |
| SERINC1 | serine incorporator 1 | 0.0170443 |
| ERBIN | erbb2 interacting protein | 0.0170386 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0170022 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0168469 |
| KIAA1958 | KIAA1958 | 0.0164668 |
| SNX14 | sorting nexin 14 | 0.0164631 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0163282 |
| RPS16 | ribosomal protein S16 | 0.0162334 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.0162097 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0161018 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0157089 |
| SGO2 | shugoshin 2 | 0.0156941 |
| MEF2A | myocyte enhancer factor 2A | 0.0156276 |
| SEPTIN2 | septin 2 | 0.0153545 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0152734 |
| MCL1 | myeloid cell leukemia 1 | 0.0152021 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0152018 |
| BARX2 | BARX homeobox 2 | 0.0151857 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0151598 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0150761 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0149572 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0148848 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0148685 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.014867 |
| FAM13A | family with sequence similarity 13, member A | 0.0148211 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0146571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.176944 |
| TP63 | tumor protein p63 | -0.146617 |
| CD44 | CD44 molecule (Indian blood group) | -0.135137 |
| TMSB4X | thymosin beta 4, X-linked | -0.122674 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.110243 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.074129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0734774 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.072323 |
| HLA-B | major histocompatibility complex, class I, B | -0.0715075 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0695437 |
| CADM2 | cell adhesion molecule 2 | -0.0691608 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.066584 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0652084 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0631172 |
| EPHA4 | EPH receptor A4 | -0.0625121 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0618546 |
| CANX | calnexin | -0.0545909 |
| DST | dystonin | -0.0529946 |
| TNS3 | tensin 3 | -0.0522395 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0473817 |
| ACTG1 | actin gamma 1 | -0.0456774 |
| RPL35A | ribosomal protein L35a | -0.0455315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0429631 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0424557 |
| EHBP1 | EH domain binding protein 1 | -0.0416448 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0408956 |
| RIGI | RNA sensor RIG-I | -0.0369069 |
| RNF213 | ring finger protein 213 | -0.0352519 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0351984 |
| APP | amyloid beta (A4) precursor protein | -0.0349081 |
| DNER | delta/notch-like EGF repeat containing | -0.0345517 |
| PDE10A | phosphodiesterase 10A | -0.0342505 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0339615 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.033646 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0328657 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0325556 |
| COL5A2 | collagen, type V, alpha 2 | -0.0323833 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0321565 |
| FMNL2 | formin-like 2 | -0.0318281 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0314597 |
| EFNA5 | ephrin-A5 | -0.0312412 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0304879 |
| TMEM123 | transmembrane protein 123 | -0.0302833 |
| POTEF | POTE ankyrin domain family, member F | -0.030267 |
| SRGN | serglycin | -0.0298282 |
| UBC | ubiquitin C | -0.0293669 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0290195 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0289476 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0283875 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.028361 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0282016 |
| RPS23 | ribosomal protein S23 | -0.0276817 |
| HDAC9 | histone deacetylase 9 | -0.0273292 |
| TGM2 | transglutaminase 2 | -0.0271835 |
| HMGA1 | high mobility group AT-hook 1 | -0.0269362 |
| DENND1A | DENN/MADD domain containing 1A | -0.026795 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0264354 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0261808 |
| WDR27 | WD repeat domain 27 | -0.0255235 |
| SP100 | SP100 nuclear antigen | -0.025316 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0251535 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0250364 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0245774 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0245745 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0245496 |
| MYOF | myoferlin | -0.0244111 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243234 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0241051 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0239194 |
| WASF2 | WAS protein family, member 2 | -0.0234388 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0233829 |
| AHNAK | AHNAK nucleoprotein | -0.0232372 |
| TAPBP | TAP binding protein (tapasin) | -0.0228948 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0224178 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0221687 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0221345 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0220295 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0219931 |
| CMIP | c-Maf inducing protein | -0.0219283 |
| GLG1 | golgi glycoprotein 1 | -0.0218155 |
| FNBP4 | formin binding protein 4 | -0.0215576 |
| RPL8 | ribosomal protein L8 | -0.0215415 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0212739 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0210575 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0209651 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0208802 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0208422 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0206084 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0205548 |
| CUX1 | cut-like homeobox 1 | -0.0204349 |
| VIM | vimentin | -0.020403 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0202886 |
| UBE3C | ubiquitin protein ligase E3C | -0.0201979 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0199291 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0197877 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0197289 |
| WDR43 | WD repeat domain 43 | -0.0196236 |
| SLC38A1 | solute carrier family 38, member 1 | -0.019607 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.019483 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0193307 |
