| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0972448 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0938992 |
| MT2A | metallothionein 2A | 0.092228 |
| TMEM165 | transmembrane protein 165 | 0.0623114 |
| NGLY1 | N-glycanase 1 | 0.0596036 |
| MKI67 | marker of proliferation Ki-67 | 0.0525191 |
| CES1 | carboxylesterase 1 | 0.0495438 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.045964 |
| NDRG1 | N-myc downstream regulated 1 | 0.0412633 |
| RPS3 | ribosomal protein S3 | 0.0410417 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0407984 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.038276 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0365598 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0363095 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.035353 |
| HYOU1 | hypoxia up-regulated 1 | 0.0335612 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0333511 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0329057 |
| SEPTIN2 | septin 2 | 0.0328168 |
| ARRDC3 | arrestin domain containing 3 | 0.0320389 |
| OGA | O-GlcNAcase | 0.0320081 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0317047 |
| ZNF292 | zinc finger protein 292 | 0.0314281 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0306973 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0298404 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0296422 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0290358 |
| FTL | ferritin, light polypeptide | 0.0281634 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0278373 |
| TMEM45B | transmembrane protein 45B | 0.0262376 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0260479 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0256436 |
| DTNA | dystrobrevin, alpha | 0.0248372 |
| RUNX1 | runt-related transcription factor 1 | 0.0244625 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0243924 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0236329 |
| WDR26 | WD repeat domain 26 | 0.0235447 |
| RTN4 | reticulon 4 | 0.0232911 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0229209 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.022462 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0222449 |
| WDR45B | WD repeat domain 45B | 0.0211865 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0205136 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0203176 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0200047 |
| RPS12 | ribosomal protein S12 | 0.0197497 |
| RNF149 | ring finger protein 149 | 0.0196626 |
| PYGL | phosphorylase, glycogen, liver | 0.0192678 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0192421 |
| HELZ | helicase with zinc finger | 0.0192145 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0191407 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.019117 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0189443 |
| YTHDC1 | YTH domain containing 1 | 0.0187814 |
| SRP54 | signal recognition particle 54kDa | 0.0187044 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0186977 |
| YEATS2 | YEATS domain containing 2 | 0.0186667 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0186352 |
| NEK7 | NIMA-related kinase 7 | 0.0185516 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0181199 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0179369 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0178724 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.0177634 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0176115 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0176107 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0174487 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0170614 |
| FRY | furry homolog (Drosophila) | 0.0169719 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0167844 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0166674 |
| ATP13A3 | ATPase type 13A3 | 0.0165424 |
| TMEM87A | transmembrane protein 87A | 0.0164536 |
| ZNF148 | zinc finger protein 148 | 0.0164176 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0163419 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0163381 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0161657 |
| AGO2 | argonaute RISC catalytic component 2 | 0.016062 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0160577 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0160237 |
| MYO1B | myosin IB | 0.0157858 |
| RPL37A | ribosomal protein L37a | 0.0153393 |
| SUCO | SUN domain containing ossification factor | 0.0152239 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0152217 |
| CUL3 | cullin 3 | 0.0151479 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0151409 |
| TMF1 | TATA element modulatory factor 1 | 0.0151251 |
| FAM117B | family with sequence similarity 117, member B | 0.0150473 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0149572 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0148622 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0147831 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0147785 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0147107 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0146769 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0145934 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0145812 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0144981 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0144307 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0142649 |
| PCBP2 | poly(rC) binding protein 2 | 0.0142493 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0140789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.249175 |
| ASPH | aspartate beta-hydroxylase | -0.162526 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.149429 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.139275 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0948232 |
| LMO7 | LIM domain 7 | -0.0937908 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0889147 |
| ACTG1 | actin gamma 1 | -0.0781641 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0766599 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0758486 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0734052 |
| INTS6 | integrator complex subunit 6 | -0.0709675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0705689 |
| LAMC2 | laminin, gamma 2 | -0.0688246 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0640921 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0605125 |
| MYOF | myoferlin | -0.0595559 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0591618 |
| RNF213 | ring finger protein 213 | -0.0591398 |
| EFNA5 | ephrin-A5 | -0.0575979 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0567115 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0565253 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0562499 |
| KRT7 | keratin 7, type II | -0.0561494 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.054547 |
| AHNAK | AHNAK nucleoprotein | -0.0540486 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0535521 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0533574 |
| ANXA2 | annexin A2 | -0.0521866 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0505478 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.047759 |
| S100A10 | S100 calcium binding protein A10 | -0.046126 |
| MYO1E | myosin IE | -0.0454204 |
| CCND1 | cyclin D1 | -0.0450289 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0449684 |
| SCEL | sciellin | -0.0447973 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0436728 |
| HOMER1 | homer scaffolding protein 1 | -0.0402423 |
| KRT18 | keratin 18, type I | -0.0398771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0389445 |
| CUX1 | cut-like homeobox 1 | -0.0375293 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0367228 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0363356 |
| VCL | vinculin | -0.0355835 |
| SP100 | SP100 nuclear antigen | -0.0335989 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0334801 |
| DSCAM | Down syndrome cell adhesion molecule | -0.033183 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0331669 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0328848 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0322914 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0319365 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0318702 |
| GRAMD1B | GRAM domain containing 1B | -0.0318262 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0314973 |
| TNS3 | tensin 3 | -0.0314504 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0311096 |
| NABP1 | nucleic acid binding protein 1 | -0.031023 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0306374 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0305925 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.030526 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.030451 |
| TMSB10 | thymosin beta 10 | -0.0303709 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0302078 |
| KRT8 | keratin 8, type II | -0.0301185 |
| EGR1 | early growth response 1 | -0.0301027 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0298564 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0298075 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0296804 |
| CMIP | c-Maf inducing protein | -0.0294922 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0290102 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0287509 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0282538 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0281848 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0279566 |
| PRKCA | protein kinase C, alpha | -0.0277116 |
| SMYD3 | SET and MYND domain containing 3 | -0.0276457 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0276425 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0273586 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0268179 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0266879 |
| SLTM | SAFB-like, transcription modulator | -0.026513 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0260899 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0258818 |
| MAP7 | microtubule-associated protein 7 | -0.0252539 |
| SVIL | supervillin | -0.0252009 |
| PATJ | PATJ crumbs cell polarity complex component | -0.025075 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0249349 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0244079 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0243375 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0240789 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0240132 |
| TPM4 | tropomyosin 4 | -0.0239984 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234966 |
| FOXP1 | forkhead box P1 | -0.0232422 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0232143 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0231528 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.023145 |
| CTBP2 | C-terminal binding protein 2 | -0.0230023 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0229975 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0228888 |
