| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.183381 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.111221 |
| FNDC3B | fibronectin type III domain containing 3B | 0.102408 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0939816 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0855145 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0854805 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0831943 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0815988 |
| CD44 | CD44 molecule (Indian blood group) | 0.0769412 |
| RAD51B | RAD51 paralog B | 0.0758874 |
| GPC6 | glypican 6 | 0.0714512 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0675802 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0646283 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0637114 |
| FAM13A | family with sequence similarity 13, member A | 0.0612363 |
| ADD3 | adducin 3 (gamma) | 0.060709 |
| OSMR | oncostatin M receptor | 0.0572909 |
| EFNA5 | ephrin-A5 | 0.0568156 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0567247 |
| SMAD3 | SMAD family member 3 | 0.0566235 |
| ANGPTL4 | angiopoietin-like 4 | 0.0548502 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0536789 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0531557 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0520505 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0518687 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0510136 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0507219 |
| PRELID2 | PRELI domain containing 2 | 0.0490516 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0478065 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.047793 |
| NAV2 | neuron navigator 2 | 0.0466846 |
| EGFR | epidermal growth factor receptor | 0.044804 |
| FLNB | filamin B, beta | 0.0446573 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0436138 |
| ZNF292 | zinc finger protein 292 | 0.0431084 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.042714 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.042284 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0422346 |
| NRP1 | neuropilin 1 | 0.0421589 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0420672 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0418327 |
| ETV6 | ets variant 6 | 0.0418153 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0414485 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0414334 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0411583 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0406725 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0393471 |
| JMJD1C | jumonji domain containing 1C | 0.0393051 |
| CDCP1 | CUB domain containing protein 1 | 0.0388964 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0384941 |
| YEATS2 | YEATS domain containing 2 | 0.0384427 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0380359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0375477 |
| HAS2 | hyaluronan synthase 2 | 0.0362969 |
| USP34 | ubiquitin specific peptidase 34 | 0.0362373 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0360843 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0358979 |
| CD109 | CD109 molecule | 0.0357831 |
| PFKP | phosphofructokinase, platelet | 0.0357071 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0352039 |
| IL6ST | interleukin 6 signal transducer | 0.0346539 |
| FBXO32 | F-box protein 32 | 0.0341635 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0336672 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0334512 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0331848 |
| ITGAV | integrin, alpha V | 0.0331629 |
| VMP1 | vacuole membrane protein 1 | 0.0331152 |
| MCL1 | myeloid cell leukemia 1 | 0.0329129 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0322989 |
| CDK19 | cyclin-dependent kinase 19 | 0.0321875 |
| SLTM | SAFB-like, transcription modulator | 0.0321707 |
| MYO1E | myosin IE | 0.0319447 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0318847 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0315981 |
| RTN4 | reticulon 4 | 0.0315584 |
| ENO1 | enolase 1, (alpha) | 0.0315468 |
| OGA | O-GlcNAcase | 0.031426 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.031071 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0308439 |
| RUNX2 | runt-related transcription factor 2 | 0.0307949 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0307927 |
| ATP13A3 | ATPase type 13A3 | 0.0307236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0304304 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0301335 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0300048 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0299562 |
| KLF6 | Kruppel-like factor 6 | 0.029698 |
| MSN | moesin | 0.0294915 |
| CA12 | carbonic anhydrase XII | 0.029337 |
| RUNX1 | runt-related transcription factor 1 | 0.0292187 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0288018 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0285717 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0279961 |
| AOPEP | aminopeptidase O (putative) | 0.0279866 |
| PHF21A | PHD finger protein 21A | 0.0276099 |
| CDK17 | cyclin-dependent kinase 17 | 0.0269225 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0266583 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0266047 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0261949 |
| RARB | retinoic acid receptor, beta | 0.0261522 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.15721 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123102 |
| CDH13 | cadherin 13 | -0.122438 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0919231 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0878851 |
| NRG1 | neuregulin 1 | -0.0855135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0764273 |
| MTSS1 | metastasis suppressor 1 | -0.0749685 |
| STC1 | stanniocalcin 1 | -0.0672708 |
| VIM | vimentin | -0.0668985 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0637251 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0620073 |
| FAM20C | family with sequence similarity 20, member C | -0.0608688 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0594685 |
| AADAC | arylacetamide deacetylase | -0.0592154 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0590368 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.056467 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0503476 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0495838 |
| INTS6 | integrator complex subunit 6 | -0.0487053 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0466117 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0465225 |
| RPLP1 | ribosomal protein, large, P1 | -0.0450846 |
| RPL35A | ribosomal protein L35a | -0.0450836 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0444236 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0441047 |
| SP100 | SP100 nuclear antigen | -0.0432496 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0425746 |
| CDK14 | cyclin-dependent kinase 14 | -0.0421334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420922 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0404772 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.038282 |
| RPL34 | ribosomal protein L34 | -0.0382564 |
| FTL | ferritin, light polypeptide | -0.0381271 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0379849 |
| TMSB4X | thymosin beta 4, X-linked | -0.0378326 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0373981 |
| RPS8 | ribosomal protein S8 | -0.0366246 |
| VRK2 | vaccinia related kinase 2 | -0.0356602 |
| RPS6 | ribosomal protein S6 | -0.0349678 |
| PTMA | prothymosin, alpha | -0.0343329 |
| YBX1 | Y box binding protein 1 | -0.0343085 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0336383 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0335056 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0334716 |
| IL1B | interleukin 1, beta | -0.0331392 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0330764 |
| NLK | nemo-like kinase | -0.0327958 |
| TGFB1 | transforming growth factor, beta 1 | -0.0321911 |
| FBN1 | fibrillin 1 | -0.031623 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0314464 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0311871 |
| PARD3 | par-3 family cell polarity regulator | -0.030857 |
| RPS24 | ribosomal protein S24 | -0.030805 |
| DENND1A | DENN/MADD domain containing 1A | -0.0302855 |
| NUMB | numb homolog (Drosophila) | -0.0299602 |
| RPS19 | ribosomal protein S19 | -0.029585 |
| FN1 | fibronectin 1 | -0.0292393 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0287711 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0286384 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0286253 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0285417 |
| UBC | ubiquitin C | -0.0282187 |
| FRMD4A | FERM domain containing 4A | -0.0281984 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0278773 |
| DNER | delta/notch-like EGF repeat containing | -0.0276029 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.027131 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0269236 |
| POTEF | POTE ankyrin domain family, member F | -0.0267097 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0267096 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0264119 |
| GLIS3 | GLIS family zinc finger 3 | -0.026391 |
| RPS21 | ribosomal protein S21 | -0.0260292 |
| RPLP0 | ribosomal protein, large, P0 | -0.0260238 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0257196 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0254258 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0249344 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0246564 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0245601 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0245449 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0240303 |
| DMXL1 | Dmx-like 1 | -0.0239929 |
| DENND4A | DENN/MADD domain containing 4A | -0.0239099 |
| RPL32 | ribosomal protein L32 | -0.0235495 |
| ATG7 | autophagy related 7 | -0.0234967 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0234099 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0233541 |
| RPS23 | ribosomal protein S23 | -0.023225 |
| HMGA2 | high mobility group AT-hook 2 | -0.0227778 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0226198 |
| ACTG1 | actin gamma 1 | -0.0225852 |
| GNAS | GNAS complex locus | -0.0225658 |
| PRRX1 | paired related homeobox 1 | -0.0224064 |
| GLCCI1 | glucocorticoid induced 1 | -0.0221861 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0219967 |
| CTBP2 | C-terminal binding protein 2 | -0.0219528 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0219235 |
| RCOR1 | REST corepressor 1 | -0.0218947 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.021875 |
| CP | ceruloplasmin (ferroxidase) | -0.0218237 |
