| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.17056 |
| NDRG1 | N-myc downstream regulated 1 | 0.17022 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.167912 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125266 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.120777 |
| FAM13A | family with sequence similarity 13, member A | 0.112898 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.107828 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0893863 |
| SBF2 | SET binding factor 2 | 0.0852178 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0841047 |
| RPS3 | ribosomal protein S3 | 0.0820602 |
| PDE10A | phosphodiesterase 10A | 0.0744606 |
| RPL12 | ribosomal protein L12 | 0.0693827 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0691306 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.062735 |
| FNDC3B | fibronectin type III domain containing 3B | 0.060941 |
| RPLP1 | ribosomal protein, large, P1 | 0.0598056 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0590245 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0585727 |
| CA12 | carbonic anhydrase XII | 0.0579719 |
| ASPH | aspartate beta-hydroxylase | 0.0576653 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0565304 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.055045 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0550041 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0548419 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0533243 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0531551 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0531074 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0523696 |
| RPS12 | ribosomal protein S12 | 0.0522178 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0506502 |
| HMGB2 | high mobility group box 2 | 0.0482258 |
| RPL27A | ribosomal protein L27a | 0.0478464 |
| PCBP2 | poly(rC) binding protein 2 | 0.0472073 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0457539 |
| NAV2 | neuron navigator 2 | 0.045696 |
| NGLY1 | N-glycanase 1 | 0.0456046 |
| RAD51B | RAD51 paralog B | 0.0450089 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0448422 |
| ABLIM1 | actin binding LIM protein 1 | 0.0444495 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0430023 |
| TPM3 | tropomyosin 3 | 0.0421865 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0420478 |
| ANLN | anillin, actin binding protein | 0.0420405 |
| LDHA | lactate dehydrogenase A | 0.0408147 |
| RPS8 | ribosomal protein S8 | 0.0407017 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0401406 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0397624 |
| ACTN4 | actinin, alpha 4 | 0.0395692 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0393065 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0392741 |
| ZFR | zinc finger RNA binding protein | 0.0392254 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0391561 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0391157 |
| MKI67 | marker of proliferation Ki-67 | 0.0390676 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0389892 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0389301 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0388542 |
| NUP58 | nucleoporin 58 | 0.0387644 |
| RYBP | RING1 and YY1 binding protein | 0.0386906 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0384355 |
| RPL4 | ribosomal protein L4 | 0.0382351 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0377791 |
| USP34 | ubiquitin specific peptidase 34 | 0.0375088 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0363669 |
| MIS18BP1 | MIS18 binding protein 1 | 0.036281 |
| DTNA | dystrobrevin, alpha | 0.0355839 |
| METTL15 | methyltransferase like 15 | 0.0348722 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0345963 |
| RUNX1 | runt-related transcription factor 1 | 0.0345416 |
| KIAA1217 | KIAA1217 | 0.034535 |
| ZNF292 | zinc finger protein 292 | 0.0343487 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0341298 |
| TKT | transketolase | 0.0337431 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.033396 |
| MCL1 | myeloid cell leukemia 1 | 0.0332719 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0331266 |
| MT2A | metallothionein 2A | 0.0324904 |
| RACK1 | receptor for activated C kinase 1 | 0.0323469 |
| PKM | pyruvate kinase, muscle | 0.0323443 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0319966 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0319314 |
| PRELID2 | PRELI domain containing 2 | 0.0317088 |
| SETD5 | SET domain containing 5 | 0.0314894 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0313707 |
| RPL10A | ribosomal protein L10a | 0.0313636 |
| GOLGA4 | golgin A4 | 0.0313025 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0312348 |
| ATP11A | ATPase, class VI, type 11A | 0.0311546 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0310384 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0309975 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0309162 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0309131 |
| RPS13 | ribosomal protein S13 | 0.0305992 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0303564 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0300815 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0298802 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0297681 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0294192 |
| RPL15 | ribosomal protein L15 | 0.029361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.141686 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130204 |
| S100A9 | S100 calcium binding protein A9 | -0.104296 |
| NCOA3 | nuclear receptor coactivator 3 | -0.099171 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0983588 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0769624 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0745315 |
| LMO7 | LIM domain 7 | -0.0687937 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0679703 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.056916 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0555866 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0551338 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0546287 |
| S100A10 | S100 calcium binding protein A10 | -0.0542816 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0527816 |
| ATOSA | atos homolog A | -0.0521205 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.050867 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0506907 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0499513 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0498172 |
| RPL32 | ribosomal protein L32 | -0.0494117 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0491785 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0484825 |
| SFTPA2 | surfactant protein A2 | -0.0482195 |
| YBX3 | Y box binding protein 3 | -0.0480209 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0479627 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0471256 |
| ABHD17C | abhydrolase domain containing 17C | -0.0470144 |
| AHNAK | AHNAK nucleoprotein | -0.0467465 |
| RPL35A | ribosomal protein L35a | -0.0465887 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0465671 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0462148 |
| TOP1 | topoisomerase (DNA) I | -0.0457181 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.045617 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0456045 |
| MATR3 | matrin 3 | -0.0454771 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0447722 |
| RPS19 | ribosomal protein S19 | -0.0438957 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0438775 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0437573 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0436186 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0432632 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0430266 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0427747 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0420716 |
| CLINT1 | clathrin interactor 1 | -0.0420358 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0415184 |
| DIDO1 | death inducer-obliterator 1 | -0.0413786 |
| CCNI | cyclin I | -0.0413215 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0407025 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0405156 |
| THBS1 | thrombospondin 1 | -0.0400306 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0400295 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.0397057 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0396034 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0394623 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0393706 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0392664 |
| LIMA1 | LIM domain and actin binding 1 | -0.0392627 |
| MORF4L1 | mortality factor 4 like 1 | -0.0390218 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.039016 |
| MEF2A | myocyte enhancer factor 2A | -0.0389973 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.038858 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0387483 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0383543 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.038294 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0382118 |
| RBM47 | RNA binding motif protein 47 | -0.0380995 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0380882 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0377964 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0372427 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0371868 |
| CDC27 | cell division cycle 27 | -0.0371662 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0371297 |
| FTL | ferritin, light polypeptide | -0.037009 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0369784 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0369557 |
| UBAP1 | ubiquitin associated protein 1 | -0.0363872 |
| RIOK3 | RIO kinase 3 | -0.0360269 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0357588 |
| MSI2 | musashi RNA-binding protein 2 | -0.0357311 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0356709 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0356337 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0352486 |
| TMSB10 | thymosin beta 10 | -0.0350106 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0348188 |
| SQSTM1 | sequestosome 1 | -0.0348004 |
| ATP11B | ATPase, class VI, type 11B | -0.0347524 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0346575 |
| MFSD14A | major facilitator superfamily domain containing 14A | -0.0342233 |
| FN1 | fibronectin 1 | -0.034158 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0340427 |
| TPM4 | tropomyosin 4 | -0.0339681 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0339593 |
| TRIM33 | tripartite motif containing 33 | -0.0338887 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.033569 |
| SP100 | SP100 nuclear antigen | -0.0332774 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0332292 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0331452 |
| LAMB1 | laminin, beta 1 | -0.0327497 |
