| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD51B | RAD51 paralog B | 0.081043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0713867 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0580161 |
| MCL1 | myeloid cell leukemia 1 | 0.057598 |
| GRAMD1B | GRAM domain containing 1B | 0.0499785 |
| EXOC4 | exocyst complex component 4 | 0.0490851 |
| RPS3 | ribosomal protein S3 | 0.0467447 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0453445 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0433127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0407799 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0363418 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0360305 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0329637 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0312386 |
| SMYD3 | SET and MYND domain containing 3 | 0.0311378 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.031056 |
| RPS12 | ribosomal protein S12 | 0.0309221 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304753 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0302562 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0299505 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0296867 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0296621 |
| R3HDM2 | R3H domain containing 2 | 0.0295939 |
| RPS7 | ribosomal protein S7 | 0.028717 |
| CAVIN1 | caveolae associated protein 1 | 0.0284769 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0275369 |
| PRKCE | protein kinase C, epsilon | 0.0274736 |
| EXOC6B | exocyst complex component 6B | 0.0274342 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0264613 |
| DOCK5 | dedicator of cytokinesis 5 | 0.025349 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0251148 |
| ATP11A | ATPase, class VI, type 11A | 0.0250241 |
| PLCB4 | phospholipase C, beta 4 | 0.024529 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0240495 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0239403 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0237862 |
| ENO1 | enolase 1, (alpha) | 0.0237421 |
| MT2A | metallothionein 2A | 0.0237305 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0231643 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.022934 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0226591 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0221729 |
| EGR1 | early growth response 1 | 0.0221525 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0220913 |
| MKI67 | marker of proliferation Ki-67 | 0.0217744 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0216144 |
| WWOX | WW domain containing oxidoreductase | 0.0215648 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.021022 |
| CMIP | c-Maf inducing protein | 0.0208967 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0206094 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0204158 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0203909 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0201035 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0199623 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0199018 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0194403 |
| LDHA | lactate dehydrogenase A | 0.0192451 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0191176 |
| ITSN2 | intersectin 2 | 0.0190514 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0188403 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.018636 |
| TPM3 | tropomyosin 3 | 0.0183867 |
| SET | SET nuclear proto-oncogene | 0.0183622 |
| RPS2 | ribosomal protein S2 | 0.0178305 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0175854 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0175484 |
| EGFR | epidermal growth factor receptor | 0.0175455 |
| JMJD1C | jumonji domain containing 1C | 0.0174754 |
| ACTN1 | actinin, alpha 1 | 0.017248 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0172023 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0171094 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0170506 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0170493 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0169651 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0169006 |
| INTS6 | integrator complex subunit 6 | 0.0168947 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0166828 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0165454 |
| FOXP1 | forkhead box P1 | 0.0165399 |
| MED13L | mediator complex subunit 13-like | 0.0165203 |
| CIP2A | cellular inhibitor of PP2A | 0.016398 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0163672 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0162325 |
| LCLAT1 | lysocardiolipin acyltransferase 1 | 0.0161124 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0160627 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0159521 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0159399 |
| AEBP2 | AE binding protein 2 | 0.0159193 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0158955 |
| ZFHX3 | zinc finger homeobox 3 | 0.0158879 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0158353 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0156646 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0156026 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0153893 |
| DAPK3 | death-associated protein kinase 3 | 0.0153701 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0152079 |
| YBX3 | Y box binding protein 3 | 0.0151703 |
| CCDC91 | coiled-coil domain containing 91 | 0.015169 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0151391 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0151317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.485516 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.190228 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.120632 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0960707 |
| TMSB10 | thymosin beta 10 | -0.0752459 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0672859 |
| PTMA | prothymosin, alpha | -0.0615298 |
| RPL35A | ribosomal protein L35a | -0.059665 |
| CANX | calnexin | -0.0584708 |
| UBC | ubiquitin C | -0.0561425 |
| RPS21 | ribosomal protein S21 | -0.0555644 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0549218 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0487485 |
| AHNAK | AHNAK nucleoprotein | -0.0484192 |
| ACTG1 | actin gamma 1 | -0.0482545 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0480325 |
| RPL8 | ribosomal protein L8 | -0.0476654 |
| TPM2 | tropomyosin 2 (beta) | -0.047437 |
| YBX1 | Y box binding protein 1 | -0.0467338 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0456355 |
| S100A10 | S100 calcium binding protein A10 | -0.0455555 |
| RPS15 | ribosomal protein S15 | -0.0444087 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0423457 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0416059 |
| H1-0 | H1.0 linker histone | -0.0410959 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0409695 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.040739 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0399943 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.039991 |
| RPS19 | ribosomal protein S19 | -0.0395876 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0390855 |
| GNAS | GNAS complex locus | -0.0376794 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0375591 |
| RPL32 | ribosomal protein L32 | -0.0369305 |
| ZFR | zinc finger RNA binding protein | -0.0367755 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0364706 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0361622 |
| RPL23 | ribosomal protein L23 | -0.0355014 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0353127 |
| RBM39 | RNA binding motif protein 39 | -0.0349192 |
| RPL34 | ribosomal protein L34 | -0.034593 |
| VIM | vimentin | -0.0345183 |
| SPAG9 | sperm associated antigen 9 | -0.0345149 |
| WASF2 | WAS protein family, member 2 | -0.0342067 |
| TUBB | tubulin, beta class I | -0.0341159 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0337634 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330963 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0330299 |
| RPS29 | ribosomal protein S29 | -0.0326156 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0325605 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0323669 |
| DEK | DEK proto-oncogene | -0.0319726 |
| PFN1 | profilin 1 | -0.0313765 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0310269 |
| RPL12 | ribosomal protein L12 | -0.030945 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0306724 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0304634 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0303617 |
| FBXO11 | F-box protein 11 | -0.0302254 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0299628 |
| CCND2 | cyclin D2 | -0.0296825 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0295977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0286244 |
| TFG | TRK-fused gene | -0.0281907 |
| OGA | O-GlcNAcase | -0.0281094 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0277919 |
| RPL37 | ribosomal protein L37 | -0.0276569 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.027318 |
| GOLGA4 | golgin A4 | -0.0271386 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0270723 |
| RSF1 | remodeling and spacing factor 1 | -0.0270211 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0269221 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0267876 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0267024 |
| COPA | coatomer protein complex, subunit alpha | -0.0265105 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0265029 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0264959 |
| CD2AP | CD2-associated protein | -0.0264095 |
| FMNL2 | formin-like 2 | -0.0262587 |
| NF1 | neurofibromin 1 | -0.0260263 |
| TAGLN2 | transgelin 2 | -0.0256874 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0256206 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0254789 |
| POTEF | POTE ankyrin domain family, member F | -0.0253462 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0251998 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0249536 |
| TMEM131 | transmembrane protein 131 | -0.024781 |
| RPS6 | ribosomal protein S6 | -0.0247604 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0246193 |
| RPLP1 | ribosomal protein, large, P1 | -0.0244583 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0244096 |
| TMEM263 | transmembrane protein 263 | -0.0243989 |
| SRP72 | signal recognition particle 72kDa | -0.0243402 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0242826 |
| MT1X | metallothionein 1X | -0.0238909 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0237656 |
| GLO1 | glyoxalase I | -0.0237587 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0237423 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0231862 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0231075 |
