| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SRP54 | signal recognition particle 54kDa | 0.113239 |
| ZNF292 | zinc finger protein 292 | 0.109174 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0694327 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0649178 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0610319 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0551416 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0544294 |
| NCKAP1 | NCK-associated protein 1 | 0.0526408 |
| MTF2 | metal response element binding transcription factor 2 | 0.0509873 |
| PDGFC | platelet derived growth factor C | 0.0490186 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0484962 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.046581 |
| MYO10 | myosin X | 0.0463223 |
| HDAC9 | histone deacetylase 9 | 0.0455896 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0455765 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0446879 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0444448 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0432827 |
| WDR43 | WD repeat domain 43 | 0.041558 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0415125 |
| ITGAV | integrin, alpha V | 0.0405064 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0399307 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0395411 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0384362 |
| XPO1 | exportin 1 | 0.0378183 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0372137 |
| SHROOM3 | shroom family member 3 | 0.036536 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0365352 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0363307 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.035605 |
| SIK3 | SIK family kinase 3 | 0.0351347 |
| ANK2 | ankyrin 2, neuronal | 0.0349373 |
| PCBP2 | poly(rC) binding protein 2 | 0.0341452 |
| ZNF608 | zinc finger protein 608 | 0.034129 |
| RANBP9 | RAN binding protein 9 | 0.0340436 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0339911 |
| CARD16 | caspase recruitment domain family, member 16 | 0.032362 |
| TENM2 | teneurin transmembrane protein 2 | 0.0317714 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0314945 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0312039 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0309506 |
| NTM | neurotrimin | 0.0307312 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296684 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0296193 |
| VMP1 | vacuole membrane protein 1 | 0.0293492 |
| ZNF207 | zinc finger protein 207 | 0.0293066 |
| IPO7 | importin 7 | 0.0293022 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0292811 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0290312 |
| RPL5 | ribosomal protein L5 | 0.0287245 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0286886 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0286359 |
| PAIP1 | poly(A) binding protein interacting protein 1 | 0.0283575 |
| PHF21A | PHD finger protein 21A | 0.0281954 |
| ANXA1 | annexin A1 | 0.0278847 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0278496 |
| RPL21 | ribosomal protein L21 | 0.0277792 |
| QKI | QKI, KH domain containing, RNA binding | 0.0277261 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0276614 |
| RPS2 | ribosomal protein S2 | 0.0276227 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0271701 |
| GPC3 | glypican 3 | 0.027102 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0270747 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0270589 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0269784 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0269029 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0266218 |
| DIAPH3 | diaphanous-related formin 3 | 0.0264477 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0262621 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0261288 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.026113 |
| YAP1 | Yes-associated protein 1 | 0.0261116 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0260463 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0259047 |
| RPS7 | ribosomal protein S7 | 0.0257948 |
| PLPP1 | phospholipid phosphatase 1 | 0.0257865 |
| HELZ | helicase with zinc finger | 0.0255276 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.025526 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255154 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254747 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0253849 |
| METAP2 | methionyl aminopeptidase 2 | 0.0253561 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0253281 |
| MED13L | mediator complex subunit 13-like | 0.0253134 |
| PCDH18 | protocadherin 18 | 0.0250248 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.024709 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0246367 |
| SFMBT1 | Scm-like with four mbt domains 1 | 0.0245753 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0245028 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0244108 |
| NCAM2 | neural cell adhesion molecule 2 | 0.024361 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.024218 |
| NBAS | neuroblastoma amplified sequence | 0.0240606 |
| FAM168A | family with sequence similarity 168, member A | 0.0240509 |
| WWC2 | WW and C2 domain containing 2 | 0.0240293 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0239933 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0239538 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0239241 |
| RNF13 | ring finger protein 13 | 0.0232646 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0231144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.159985 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145203 |
| ACTG1 | actin gamma 1 | -0.124791 |
| PTMA | prothymosin, alpha | -0.119762 |
| RPL35A | ribosomal protein L35a | -0.0786277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0756653 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0746227 |
| RPS16 | ribosomal protein S16 | -0.0728469 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0726721 |
| COL3A1 | collagen, type III, alpha 1 | -0.0701141 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0656169 |
| PCDH9 | protocadherin 9 | -0.0630353 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0625209 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0623899 |
| TMSB10 | thymosin beta 10 | -0.0619591 |
| TMSB4X | thymosin beta 4, X-linked | -0.0609099 |
| RPL34 | ribosomal protein L34 | -0.0584606 |
| S100A10 | S100 calcium binding protein A10 | -0.0548323 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0540693 |
| RPS8 | ribosomal protein S8 | -0.0540272 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053455 |
| EMP1 | epithelial membrane protein 1 | -0.0531739 |
| GNAS | GNAS complex locus | -0.0528363 |
| AHNAK | AHNAK nucleoprotein | -0.0527024 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.051267 |
| MYL12B | myosin, light chain 12B, regulatory | -0.050778 |
| RPS6 | ribosomal protein S6 | -0.0487093 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0473982 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0473517 |
| RPS21 | ribosomal protein S21 | -0.0468388 |
| THBS1 | thrombospondin 1 | -0.0463182 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0458677 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456157 |
| RPS24 | ribosomal protein S24 | -0.045574 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0448216 |
| RPS15 | ribosomal protein S15 | -0.0432781 |
| FOXP2 | forkhead box P2 | -0.0431372 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0419843 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0414241 |
| RPL31 | ribosomal protein L31 | -0.0408631 |
| COL1A2 | collagen, type I, alpha 2 | -0.0408536 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0408514 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0408309 |
| ACTN4 | actinin, alpha 4 | -0.0396065 |
| RPL11 | ribosomal protein L11 | -0.0395779 |
| RPL37 | ribosomal protein L37 | -0.0386896 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0385722 |
| CAVIN1 | caveolae associated protein 1 | -0.0384643 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0383451 |
| MKI67 | marker of proliferation Ki-67 | -0.0377757 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.037748 |
| FBXO27 | F-box protein 27 | -0.03755 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0374295 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0373361 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372344 |
| MAP4 | microtubule-associated protein 4 | -0.037072 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0367871 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0363251 |
| WASF2 | WAS protein family, member 2 | -0.0360865 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0358978 |
| RPL8 | ribosomal protein L8 | -0.0353822 |
| RPS10 | ribosomal protein S10 | -0.0350925 |
| UBB | ubiquitin B | -0.0350716 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0347239 |
| H1-0 | H1.0 linker histone | -0.0346382 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0340769 |
| RAB31 | RAB31, member RAS oncogene family | -0.0339118 |
| RPS23 | ribosomal protein S23 | -0.0335138 |
| DEK | DEK proto-oncogene | -0.0334259 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0330683 |
| CDK12 | cyclin-dependent kinase 12 | -0.0329505 |
| POU3F2 | POU class 3 homeobox 2 | -0.0327664 |
| RPL38 | ribosomal protein L38 | -0.0313931 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0313586 |
| PARK7 | parkinson protein 7 | -0.0311452 |
| FGF13 | fibroblast growth factor 13 | -0.03106 |
| NF1 | neurofibromin 1 | -0.0309951 |
| ARF1 | ADP-ribosylation factor 1 | -0.0309895 |
| FBL | fibrillarin | -0.0309453 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.0309315 |
| UBC | ubiquitin C | -0.0305964 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0305454 |
| RPL27A | ribosomal protein L27a | -0.0302508 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0301214 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0300989 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0300791 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0299691 |
| RAB10 | RAB10, member RAS oncogene family | -0.02969 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0295777 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0288127 |
| MEIS2 | Meis homeobox 2 | -0.0286258 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0285271 |
| ZNF217 | zinc finger protein 217 | -0.0285075 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0284221 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0282839 |
| VCL | vinculin | -0.0281841 |
| RPL32 | ribosomal protein L32 | -0.0275205 |
| RLF | rearranged L-myc fusion | -0.0274639 |
| NEBL | nebulette | -0.0273494 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0271494 |
