| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.118511 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.116768 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0778605 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0664679 |
| TMSB10 | thymosin beta 10 | 0.0625076 |
| ANGPTL4 | angiopoietin-like 4 | 0.0561539 |
| PTMA | prothymosin, alpha | 0.0489098 |
| ENO1 | enolase 1, (alpha) | 0.0481001 |
| LDHA | lactate dehydrogenase A | 0.0461417 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0456538 |
| VCL | vinculin | 0.0413004 |
| RPS3 | ribosomal protein S3 | 0.0397416 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0384378 |
| L1CAM | L1 cell adhesion molecule | 0.037656 |
| HMGA2 | high mobility group AT-hook 2 | 0.03616 |
| RNF220 | ring finger protein 220 | 0.0343591 |
| MT2A | metallothionein 2A | 0.0335169 |
| NAV2 | neuron navigator 2 | 0.0325188 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0324874 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0320074 |
| RPS12 | ribosomal protein S12 | 0.031246 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0293806 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0286695 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0284563 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0269136 |
| MAP1B | microtubule-associated protein 1B | 0.026817 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0262634 |
| RPS17 | ribosomal protein S17 | 0.0262019 |
| CD109 | CD109 molecule | 0.0261053 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0260517 |
| RTN4 | reticulon 4 | 0.02598 |
| FOSL1 | FOS-like antigen 1 | 0.02577 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0256049 |
| EGFR | epidermal growth factor receptor | 0.0248605 |
| RPS7 | ribosomal protein S7 | 0.0237774 |
| MEF2A | myocyte enhancer factor 2A | 0.0237065 |
| FHL2 | four and a half LIM domains 2 | 0.0235716 |
| HYOU1 | hypoxia up-regulated 1 | 0.0234726 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0228653 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0225546 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0223209 |
| SEPTIN9 | septin 9 | 0.0217436 |
| STC2 | stanniocalcin 2 | 0.0216397 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0215779 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0205824 |
| EGR1 | early growth response 1 | 0.0203112 |
| MCL1 | myeloid cell leukemia 1 | 0.0201824 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.0193306 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0189386 |
| SYNJ2 | synaptojanin 2 | 0.0186696 |
| RPL23 | ribosomal protein L23 | 0.0173863 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0172114 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0171675 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0168418 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0165516 |
| PDE10A | phosphodiesterase 10A | 0.0164511 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0163621 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0163394 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0161339 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0161105 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0158127 |
| FLNA | filamin A, alpha | 0.0155203 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.015471 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0153323 |
| HMGB2 | high mobility group box 2 | 0.0152538 |
| ITGA6 | integrin, alpha 6 | 0.0150862 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0149756 |
| BCL10 | B-cell CLL/lymphoma 10 | 0.0149143 |
| HPCAL1 | hippocalcin-like 1 | 0.0145035 |
| NHSL1 | NHS-like 1 | 0.014357 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0142811 |
| KRT18 | keratin 18, type I | 0.0142282 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0139333 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0138852 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0138309 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0137908 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0136341 |
| RAD51B | RAD51 paralog B | 0.013626 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0135055 |
| RNF213 | ring finger protein 213 | 0.013336 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0133108 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.013097 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0130739 |
| FTL | ferritin, light polypeptide | 0.0130448 |
| SNX3 | sorting nexin 3 | 0.0129442 |
| CMIP | c-Maf inducing protein | 0.0129046 |
| ATXN2L | ataxin 2-like | 0.0128275 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0125812 |
| EHBP1 | EH domain binding protein 1 | 0.0124289 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0123165 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0123055 |
| MKI67 | marker of proliferation Ki-67 | 0.0122782 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0120864 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0120528 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0119875 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0119651 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0119192 |
| KMT5B | lysine methyltransferase 5B | 0.0117435 |
| MYO10 | myosin X | 0.0116809 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0116579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.370734 |
| FBL | fibrillarin | -0.146079 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.14566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.118511 |
| ACTG1 | actin gamma 1 | -0.089823 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0874797 |
| UBC | ubiquitin C | -0.0830948 |
| ACTN4 | actinin, alpha 4 | -0.082073 |
| AHNAK | AHNAK nucleoprotein | -0.0801314 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0755436 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0742058 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0722142 |
| RPS16 | ribosomal protein S16 | -0.0708073 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0662578 |
| TXNRD1 | thioredoxin reductase 1 | -0.0661651 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0621562 |
| RPL35A | ribosomal protein L35a | -0.0619963 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.06153 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0546711 |
| SMAD3 | SMAD family member 3 | -0.0533558 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0531071 |
| ZFP36 | ZFP36 ring finger protein | -0.0525057 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0488251 |
| CANX | calnexin | -0.0462684 |
| ZNF780B | zinc finger protein 780B | -0.0460622 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0451712 |
| SFTPA2 | surfactant protein A2 | -0.0446368 |
| SPAG9 | sperm associated antigen 9 | -0.044218 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0425627 |
| ASPH | aspartate beta-hydroxylase | -0.0424884 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0409638 |
| CD44 | CD44 molecule (Indian blood group) | -0.0394038 |
| YBX1 | Y box binding protein 1 | -0.0393437 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0385225 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0384942 |
| NUP98 | nucleoporin 98kDa | -0.038122 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0375717 |
| S100A10 | S100 calcium binding protein A10 | -0.0365269 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0360003 |
| RBM39 | RNA binding motif protein 39 | -0.0348197 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0344863 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0344744 |
| CUL4B | cullin 4B | -0.0334537 |
| GOLGB1 | golgin B1 | -0.032908 |
| RPS2 | ribosomal protein S2 | -0.0323871 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320444 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0320106 |
| CDK13 | cyclin-dependent kinase 13 | -0.0318077 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0317445 |
| ATF6 | activating transcription factor 6 | -0.0315026 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0313958 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.03131 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0312701 |
| RPL28 | ribosomal protein L28 | -0.0310561 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0308137 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0307765 |
| ARRDC3 | arrestin domain containing 3 | -0.0305473 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0304008 |
| RPL4 | ribosomal protein L4 | -0.0301975 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.029838 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0298247 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0297799 |
| RPL8 | ribosomal protein L8 | -0.0293641 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0290971 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0290459 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0290306 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0290278 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0290058 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.028829 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0282802 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0281541 |
| NOP58 | NOP58 ribonucleoprotein | -0.0280595 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0278516 |
| BRD2 | bromodomain containing 2 | -0.0268729 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0267393 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0267026 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0264631 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0263377 |
| FOXO3 | forkhead box O3 | -0.0260152 |
| JAK1 | Janus kinase 1 | -0.0258638 |
| JMJD1C | jumonji domain containing 1C | -0.0258148 |
| OGA | O-GlcNAcase | -0.0256967 |
| TAOK1 | TAO kinase 1 | -0.0256826 |
| WDR45B | WD repeat domain 45B | -0.0255347 |
| CTTN | cortactin | -0.025491 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0252433 |
| TAPBP | TAP binding protein (tapasin) | -0.025184 |
| GLG1 | golgi glycoprotein 1 | -0.0248165 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0247293 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.024207 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0241914 |
| DEK | DEK proto-oncogene | -0.0240824 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.023885 |
| MATR3 | matrin 3 | -0.0238412 |
| CCND1 | cyclin D1 | -0.0236858 |
| TMSB4X | thymosin beta 4, X-linked | -0.0232431 |
| THOC2 | THO complex 2 | -0.0230217 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0228584 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0227294 |
| RAB10 | RAB10, member RAS oncogene family | -0.0223693 |
