| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.109404 |
| LAMA4 | laminin, alpha 4 | 0.0837699 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0779402 |
| MUC4 | mucin 4, cell surface associated | 0.076003 |
| LAMC2 | laminin, gamma 2 | 0.0728968 |
| LDHA | lactate dehydrogenase A | 0.0681887 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0681788 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0615273 |
| LAMB3 | laminin, beta 3 | 0.0578256 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0577022 |
| ANXA2 | annexin A2 | 0.0571882 |
| MKI67 | marker of proliferation Ki-67 | 0.0560321 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0544775 |
| RUNX1 | runt-related transcription factor 1 | 0.0538556 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0510885 |
| ASPH | aspartate beta-hydroxylase | 0.0496932 |
| PLAT | plasminogen activator, tissue | 0.0474677 |
| ENO1 | enolase 1, (alpha) | 0.0462845 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0460212 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0448841 |
| RPS3 | ribosomal protein S3 | 0.0434369 |
| PGK1 | phosphoglycerate kinase 1 | 0.0410329 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0407904 |
| KRT18 | keratin 18, type I | 0.0403785 |
| EGFR | epidermal growth factor receptor | 0.0398962 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0392772 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0390154 |
| PLAU | plasminogen activator, urokinase | 0.0380596 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0377697 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0366144 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0358721 |
| VCL | vinculin | 0.0357004 |
| MUC16 | mucin 16, cell surface associated | 0.0355727 |
| SLTM | SAFB-like, transcription modulator | 0.0351743 |
| MYO6 | myosin VI | 0.0350848 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.035005 |
| FLNB | filamin B, beta | 0.034958 |
| KIF13B | kinesin family member 13B | 0.0348794 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0343531 |
| ANLN | anillin, actin binding protein | 0.0342073 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0334249 |
| MTAP | methylthioadenosine phosphorylase | 0.0332191 |
| FRMD5 | FERM domain containing 5 | 0.0329817 |
| ITGA6 | integrin, alpha 6 | 0.0328516 |
| SVIL | supervillin | 0.0327851 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0322169 |
| C3 | complement component 3 | 0.0321487 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0319653 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.031362 |
| DSG2 | desmoglein 2 | 0.0307458 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0306378 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0303533 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0302512 |
| MT2A | metallothionein 2A | 0.0301945 |
| RNF213 | ring finger protein 213 | 0.0297751 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0295971 |
| EFNA5 | ephrin-A5 | 0.0294711 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0291358 |
| ETV6 | ets variant 6 | 0.0283905 |
| KRT19 | keratin 19, type I | 0.0283773 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0281807 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0278712 |
| FAM3C | family with sequence similarity 3, member C | 0.0276838 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0273352 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0272388 |
| NRP1 | neuropilin 1 | 0.0270789 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0268444 |
| ITGB4 | integrin, beta 4 | 0.026826 |
| EZR | ezrin | 0.026719 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0267176 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0264715 |
| FHIT | fragile histidine triad | 0.0262733 |
| APP | amyloid beta (A4) precursor protein | 0.0260235 |
| TPI1 | triosephosphate isomerase 1 | 0.0259915 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0259623 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.025941 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0255862 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0248087 |
| MYOF | myoferlin | 0.0242576 |
| RASAL2 | RAS protein activator like 2 | 0.0239212 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0238383 |
| TPM4 | tropomyosin 4 | 0.0233982 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0233465 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.023303 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0232539 |
| ANXA11 | annexin A11 | 0.0227927 |
| NAV2 | neuron navigator 2 | 0.0226439 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0225825 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0225227 |
| B2M | beta-2-microglobulin | 0.0223821 |
| PLK2 | polo-like kinase 2 | 0.0223738 |
| DIAPH3 | diaphanous-related formin 3 | 0.0223454 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0222938 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0222591 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0221248 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0221197 |
| WAPL | WAPL cohesin release factor | 0.0219239 |
| ENOSF1 | enolase superfamily member 1 | 0.021865 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0218615 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0216244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.410229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.15853 |
| ACTG1 | actin gamma 1 | -0.139852 |
| RPL35A | ribosomal protein L35a | -0.106433 |
| RPS6 | ribosomal protein S6 | -0.10638 |
| POTEF | POTE ankyrin domain family, member F | -0.089615 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0817861 |
| PTMA | prothymosin, alpha | -0.0796915 |
| RPS15 | ribosomal protein S15 | -0.0740849 |
| TMSB4X | thymosin beta 4, X-linked | -0.0698485 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0688729 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0664423 |
| RPS23 | ribosomal protein S23 | -0.0662121 |
| RPLP1 | ribosomal protein, large, P1 | -0.0657245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0626646 |
| RPS19 | ribosomal protein S19 | -0.0620645 |
| RPL8 | ribosomal protein L8 | -0.0597253 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0595018 |
| EMP1 | epithelial membrane protein 1 | -0.058508 |
| RPL23 | ribosomal protein L23 | -0.0582442 |
| RPL34 | ribosomal protein L34 | -0.0538341 |
| RPS8 | ribosomal protein S8 | -0.0530003 |
| KRT7 | keratin 7, type II | -0.0524771 |
| KRT8 | keratin 8, type II | -0.0466817 |
| RPL28 | ribosomal protein L28 | -0.0465984 |
| TAPBP | TAP binding protein (tapasin) | -0.0455136 |
| PCBP2 | poly(rC) binding protein 2 | -0.0454728 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0454498 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0451726 |
| KRT17 | keratin 17, type I | -0.0444071 |
| RPS5 | ribosomal protein S5 | -0.0443633 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0442108 |
| UBC | ubiquitin C | -0.0441262 |
| RPS21 | ribosomal protein S21 | -0.0434948 |
| VEGFA | vascular endothelial growth factor A | -0.0428629 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0426831 |
| RPS13 | ribosomal protein S13 | -0.0416847 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0413773 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0402633 |
| G0S2 | G0/G1 switch 2 | -0.0381478 |
| BRD2 | bromodomain containing 2 | -0.0371001 |
| RPS14 | ribosomal protein S14 | -0.0364181 |
| S100A10 | S100 calcium binding protein A10 | -0.0353116 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0348591 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0344127 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0343553 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0337116 |
| RPL37 | ribosomal protein L37 | -0.0325678 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0321448 |
| RPL32 | ribosomal protein L32 | -0.0320844 |
| ASTN2 | astrotactin 2 | -0.0319395 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0312703 |
| RPS29 | ribosomal protein S29 | -0.0312123 |
| DEK | DEK proto-oncogene | -0.0308654 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0308347 |
| RPS11 | ribosomal protein S11 | -0.0303356 |
| RND3 | Rho family GTPase 3 | -0.0301467 |
| RPS24 | ribosomal protein S24 | -0.0300475 |
| RPL11 | ribosomal protein L11 | -0.0299334 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0288557 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0281538 |
| INTS6 | integrator complex subunit 6 | -0.0279101 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0278735 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0276884 |
| RPL30 | ribosomal protein L30 | -0.026944 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268483 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0264063 |
| RPL39 | ribosomal protein L39 | -0.0261431 |
| HLA-B | major histocompatibility complex, class I, B | -0.0260483 |
| BBX | bobby sox homolog (Drosophila) | -0.0258508 |
| CCND1 | cyclin D1 | -0.025736 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.025668 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0254829 |
| HMGA1 | high mobility group AT-hook 1 | -0.0253736 |
| ATF3 | activating transcription factor 3 | -0.0252708 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0252589 |
| DSTN | destrin (actin depolymerizing factor) | -0.0252584 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0251828 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0248185 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0248174 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0246521 |
| YBX1 | Y box binding protein 1 | -0.0246211 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0242687 |
| RPL5 | ribosomal protein L5 | -0.0241835 |
| RPLP2 | ribosomal protein, large, P2 | -0.0240878 |
| RPS20 | ribosomal protein S20 | -0.0240572 |
| RPS16 | ribosomal protein S16 | -0.0239765 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0239621 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0239267 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0238447 |
| RPS4X | ribosomal protein S4, X-linked | -0.0235797 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0235496 |
| CANX | calnexin | -0.0233742 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0232561 |
| SEPTIN7 | septin 7 | -0.023229 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0231935 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0230029 |
| NPR2 | natriuretic peptide receptor 2 | -0.0228434 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0226607 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0225915 |
