| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.092715 |
| ENO1 | enolase 1, (alpha) | 0.0915967 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0871165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0857856 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0737809 |
| RAD51B | RAD51 paralog B | 0.0643139 |
| FRMD4A | FERM domain containing 4A | 0.060109 |
| NAV2 | neuron navigator 2 | 0.0560228 |
| ZNF438 | zinc finger protein 438 | 0.0499225 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0498156 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0478647 |
| EXOC4 | exocyst complex component 4 | 0.0478537 |
| ASPH | aspartate beta-hydroxylase | 0.046634 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0436824 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0421329 |
| HMGA2 | high mobility group AT-hook 2 | 0.0417654 |
| MTAP | methylthioadenosine phosphorylase | 0.0416125 |
| FLNB | filamin B, beta | 0.0405252 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0402514 |
| SMYD3 | SET and MYND domain containing 3 | 0.0388489 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0383925 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0378952 |
| RPS3 | ribosomal protein S3 | 0.0377505 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0375113 |
| FLNA | filamin A, alpha | 0.0368044 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0367734 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0356008 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.035058 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0342231 |
| RPL13A | ribosomal protein L13a | 0.03401 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0322405 |
| DGKI | diacylglycerol kinase, iota | 0.0321059 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0315516 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.031464 |
| MKI67 | marker of proliferation Ki-67 | 0.0308966 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0305554 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0299749 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0295403 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0295061 |
| ANK2 | ankyrin 2, neuronal | 0.029475 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0292707 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0288782 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0288607 |
| STK4 | serine/threonine kinase 4 | 0.0287361 |
| LAMB3 | laminin, beta 3 | 0.0282565 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0279403 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.027726 |
| CCDC91 | coiled-coil domain containing 91 | 0.0275401 |
| FHIT | fragile histidine triad | 0.027078 |
| RPS7 | ribosomal protein S7 | 0.0268644 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0268111 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0268031 |
| LDHA | lactate dehydrogenase A | 0.0260791 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0260698 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0259776 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0258616 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253427 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0253311 |
| SP100 | SP100 nuclear antigen | 0.025107 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.024904 |
| DST | dystonin | 0.0248165 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0240498 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0236843 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0234814 |
| TCF12 | transcription factor 12 | 0.0229071 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0228632 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0227697 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0226299 |
| RPS12 | ribosomal protein S12 | 0.0222237 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0218907 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0216844 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0215975 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0214946 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0213867 |
| CPQ | carboxypeptidase Q | 0.0213042 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0212977 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0210858 |
| ANO6 | anoctamin 6 | 0.020957 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.020895 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0206782 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0206777 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0206505 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0204106 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0203524 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0203509 |
| WDR37 | WD repeat domain 37 | 0.0198231 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0197052 |
| WDR33 | WD repeat domain 33 | 0.0196573 |
| CAPRIN2 | caprin family member 2 | 0.0194611 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0194104 |
| PRKCE | protein kinase C, epsilon | 0.0193799 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0193774 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.019285 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0192025 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0191019 |
| FAM13A | family with sequence similarity 13, member A | 0.0190342 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0189996 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 0.0189844 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0189627 |
| ALPK1 | alpha-kinase 1 | 0.018949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.273307 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134242 |
| ACTG1 | actin gamma 1 | -0.116621 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.110268 |
| STC1 | stanniocalcin 1 | -0.10509 |
| RPL8 | ribosomal protein L8 | -0.0864594 |
| POTEF | POTE ankyrin domain family, member F | -0.0864412 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0819209 |
| RPS6 | ribosomal protein S6 | -0.0776949 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.076277 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0726749 |
| RPL35A | ribosomal protein L35a | -0.0659235 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.065674 |
| NUP58 | nucleoporin 58 | -0.0636925 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0558212 |
| PARD3 | par-3 family cell polarity regulator | -0.0532587 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0530103 |
| HMGA1 | high mobility group AT-hook 1 | -0.0528256 |
| PTK2 | protein tyrosine kinase 2 | -0.0526721 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0518743 |
| SETD5 | SET domain containing 5 | -0.0518261 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0511642 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0491666 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0489372 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0456399 |
| RBM39 | RNA binding motif protein 39 | -0.0442221 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0438986 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0434636 |
| TPM4 | tropomyosin 4 | -0.0431869 |
| RPS21 | ribosomal protein S21 | -0.0426046 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0425134 |
| ZNF207 | zinc finger protein 207 | -0.0419309 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0415033 |
| USP3 | ubiquitin specific peptidase 3 | -0.0414531 |
| YBX1 | Y box binding protein 1 | -0.0406162 |
| FTL | ferritin, light polypeptide | -0.0403799 |
| GOLGA4 | golgin A4 | -0.0399569 |
| TTR | transthyretin | -0.0399092 |
| RHOA | ras homolog family member A | -0.0395648 |
| UBC | ubiquitin C | -0.0395193 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0390522 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0388418 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0381753 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0380077 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0376032 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0373318 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0372201 |
| SRPK2 | SRSF protein kinase 2 | -0.0363744 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0362623 |
| PFN1 | profilin 1 | -0.0362489 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0357207 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0355579 |
| TSC22D2 | TSC22 domain family, member 2 | -0.035493 |
| DIAPH3 | diaphanous-related formin 3 | -0.0353584 |
| RLF | rearranged L-myc fusion | -0.0352684 |
| RPS19 | ribosomal protein S19 | -0.0352356 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0349171 |
| ZNF292 | zinc finger protein 292 | -0.034901 |
| RPL34 | ribosomal protein L34 | -0.0344628 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.033795 |
| BBX | bobby sox homolog (Drosophila) | -0.0337335 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0334814 |
| RPLP1 | ribosomal protein, large, P1 | -0.0333634 |
| CANX | calnexin | -0.033089 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0330394 |
| TRAM1 | translocation associated membrane protein 1 | -0.0327901 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0325181 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0324042 |
| TPD52 | tumor protein D52 | -0.0321036 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0316069 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0315413 |
| RPS8 | ribosomal protein S8 | -0.0312565 |
| RHEB | Ras homolog enriched in brain | -0.0309682 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0307739 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0305521 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0299835 |
| CCNL1 | cyclin L1 | -0.0298549 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0290578 |
| DEK | DEK proto-oncogene | -0.0289389 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0289034 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0288975 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0287837 |
| FOXJ3 | forkhead box J3 | -0.0286252 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0284517 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.027725 |
| RNF145 | ring finger protein 145 | -0.0276455 |
| OLA1 | Obg-like ATPase 1 | -0.0276287 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0275985 |
| RAB18 | RAB18, member RAS oncogene family | -0.0273338 |
| RPS11 | ribosomal protein S11 | -0.0271068 |
| RPS15 | ribosomal protein S15 | -0.0268618 |
| RPS23 | ribosomal protein S23 | -0.0267773 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0267634 |
| CD2AP | CD2-associated protein | -0.0263989 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0263308 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0262366 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0261108 |
| WDR45B | WD repeat domain 45B | -0.0260146 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0256718 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0254475 |
