| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.170909 |
| MT2A | metallothionein 2A | 0.135044 |
| FTL | ferritin, light polypeptide | 0.0901815 |
| ENO1 | enolase 1, (alpha) | 0.0874406 |
| STC1 | stanniocalcin 1 | 0.0871117 |
| NDRG1 | N-myc downstream regulated 1 | 0.0834587 |
| B2M | beta-2-microglobulin | 0.0799194 |
| ANGPTL4 | angiopoietin-like 4 | 0.0776132 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0751744 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0633403 |
| VEGFA | vascular endothelial growth factor A | 0.0629662 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0622984 |
| CD109 | CD109 molecule | 0.0616658 |
| FAM13A | family with sequence similarity 13, member A | 0.0598969 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0584015 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0581021 |
| PKM | pyruvate kinase, muscle | 0.0532316 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0517117 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0511503 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0488103 |
| FOSL1 | FOS-like antigen 1 | 0.0486642 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0461897 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.044968 |
| FLNB | filamin B, beta | 0.0448162 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0416936 |
| MMP2 | matrix metallopeptidase 2 | 0.0402497 |
| MEF2A | myocyte enhancer factor 2A | 0.0398077 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0394949 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0390767 |
| LDHA | lactate dehydrogenase A | 0.0367341 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0360688 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.035783 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0356612 |
| RPS17 | ribosomal protein S17 | 0.0355137 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0351954 |
| MSN | moesin | 0.0349269 |
| TMSB10 | thymosin beta 10 | 0.0346972 |
| RPS12 | ribosomal protein S12 | 0.0325584 |
| RPS8 | ribosomal protein S8 | 0.0322065 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0321124 |
| CDK19 | cyclin-dependent kinase 19 | 0.0320876 |
| NAV2 | neuron navigator 2 | 0.0318467 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0318155 |
| RPL37A | ribosomal protein L37a | 0.0314134 |
| YEATS2 | YEATS domain containing 2 | 0.0312024 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0311434 |
| XPO1 | exportin 1 | 0.030816 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0307878 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0303762 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0289724 |
| HLA-A | major histocompatibility complex, class I, A | 0.0288587 |
| RAD51B | RAD51 paralog B | 0.0287629 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.028709 |
| MTSS1 | metastasis suppressor 1 | 0.0286719 |
| RPS3 | ribosomal protein S3 | 0.028452 |
| FHIT | fragile histidine triad | 0.0276103 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274668 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0258792 |
| PTMA | prothymosin, alpha | 0.0258349 |
| MMP12 | matrix metallopeptidase 12 | 0.025622 |
| PLIN2 | perilipin 2 | 0.0249654 |
| ZNF292 | zinc finger protein 292 | 0.0249007 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0248586 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0245935 |
| LOXL2 | lysyl oxidase-like 2 | 0.0245725 |
| FBXO32 | F-box protein 32 | 0.024246 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0237428 |
| MT1E | metallothionein 1E | 0.0236252 |
| MKI67 | marker of proliferation Ki-67 | 0.0229253 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0223998 |
| HYOU1 | hypoxia up-regulated 1 | 0.0223376 |
| ZNF148 | zinc finger protein 148 | 0.0217017 |
| CCDC88A | coiled-coil domain containing 88A | 0.0215199 |
| PFKP | phosphofructokinase, platelet | 0.0215156 |
| AXL | AXL receptor tyrosine kinase | 0.0213485 |
| ZNF395 | zinc finger protein 395 | 0.0210702 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0210583 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0210133 |
| HMGB2 | high mobility group box 2 | 0.0209275 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0207617 |
| VIM | vimentin | 0.0205041 |
| NUP58 | nucleoporin 58 | 0.020415 |
| CENPF | centromere protein F, 350/400kDa | 0.0202531 |
| RPL9 | ribosomal protein L9 | 0.0202 |
| TMEM178B | transmembrane protein 178B | 0.0201865 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0200393 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0199583 |
| C1D | C1D nuclear receptor corepressor | 0.0198468 |
| MYO1B | myosin IB | 0.0197307 |
| RPLP2 | ribosomal protein, large, P2 | 0.0195254 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0194842 |
| COL1A2 | collagen, type I, alpha 2 | 0.0193861 |
| RTN4 | reticulon 4 | 0.0192938 |
| TGM2 | transglutaminase 2 | 0.0190033 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0189451 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0189063 |
| RPL36 | ribosomal protein L36 | 0.0189038 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0188746 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0188258 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0187883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.260505 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.200835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.121156 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.095328 |
| CD44 | CD44 molecule (Indian blood group) | -0.0876829 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0833057 |
| FRMD4A | FERM domain containing 4A | -0.0797608 |
| COL1A1 | collagen, type I, alpha 1 | -0.0780929 |
| RRBP1 | ribosome binding protein 1 | -0.0691169 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.067204 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0666072 |
| AHNAK | AHNAK nucleoprotein | -0.063418 |
| PGK1 | phosphoglycerate kinase 1 | -0.0622851 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0620674 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0601886 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0587494 |
| GLIS3 | GLIS family zinc finger 3 | -0.0574874 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0505691 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0491431 |
| H1-0 | H1.0 linker histone | -0.0490602 |
| HPCAL1 | hippocalcin-like 1 | -0.0477123 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0471593 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0469108 |
| HDLBP | high density lipoprotein binding protein | -0.0460172 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0458209 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0445314 |
| ACTG1 | actin gamma 1 | -0.0429206 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.041781 |
| FAM20C | family with sequence similarity 20, member C | -0.0415956 |
| RAB1A | RAB1A, member RAS oncogene family | -0.040309 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.040181 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0399401 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0398731 |
| VCL | vinculin | -0.0386543 |
| ASPH | aspartate beta-hydroxylase | -0.0384481 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0379584 |
| COL5A3 | collagen, type V, alpha 3 | -0.0378396 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0378097 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0372932 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0371824 |
| TCF12 | transcription factor 12 | -0.0370097 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0368849 |
| MAP4 | microtubule-associated protein 4 | -0.0363629 |
| NF1 | neurofibromin 1 | -0.036119 |
| FBXO11 | F-box protein 11 | -0.0359768 |
| TPM4 | tropomyosin 4 | -0.035946 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0357486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347341 |
| UBC | ubiquitin C | -0.0347016 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034633 |
| RBM39 | RNA binding motif protein 39 | -0.0346315 |
| SMAD3 | SMAD family member 3 | -0.0345517 |
| HMGA2 | high mobility group AT-hook 2 | -0.0338756 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0337811 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0331336 |
| RSU1 | Ras suppressor protein 1 | -0.033059 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0323774 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0323072 |
| SVIL | supervillin | -0.0321896 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0321844 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0319777 |
| CANX | calnexin | -0.0317243 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0313245 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0312512 |
| ZNF644 | zinc finger protein 644 | -0.0301916 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0301264 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0298452 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0296339 |
| TPM1 | tropomyosin 1 (alpha) | -0.0292466 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0292358 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0292301 |
| HLA-B | major histocompatibility complex, class I, B | -0.0291305 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.02902 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0288218 |
| PLSCR1 | phospholipid scramblase 1 | -0.0287459 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0286996 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0286801 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283801 |
| KYNU | kynureninase | -0.0283681 |
| ATM | ATM serine/threonine kinase | -0.0283129 |
| GOLGA3 | golgin A3 | -0.028263 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279347 |
| IER3 | immediate early response 3 | -0.027926 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0277989 |
| CDK13 | cyclin-dependent kinase 13 | -0.0274095 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0268908 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0268395 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267852 |
| TNNC1 | troponin C type 1 (slow) | -0.0267399 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0265226 |
| RLIM | ring finger protein, LIM domain interacting | -0.0264959 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0264758 |
| OSMR | oncostatin M receptor | -0.0263819 |
| NBEA | neurobeachin | -0.0263528 |
| POTEF | POTE ankyrin domain family, member F | -0.0263519 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0261378 |
| PDE10A | phosphodiesterase 10A | -0.0261274 |
| INTS6 | integrator complex subunit 6 | -0.0260353 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0256161 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0255158 |
