| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANGPTL4 | angiopoietin-like 4 | 0.0467974 |
| FLNA | filamin A, alpha | 0.0432146 |
| ENO1 | enolase 1, (alpha) | 0.0418081 |
| MSN | moesin | 0.0407013 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0374282 |
| NAV2 | neuron navigator 2 | 0.0360586 |
| CENPF | centromere protein F, 350/400kDa | 0.0341198 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0325261 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0325209 |
| MT2A | metallothionein 2A | 0.0324448 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0321315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0308347 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0305204 |
| CFAP20DC | CFAP20 domain containing | 0.0303736 |
| FLNB | filamin B, beta | 0.0298409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294965 |
| LDHA | lactate dehydrogenase A | 0.0275973 |
| MKI67 | marker of proliferation Ki-67 | 0.0272919 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.025656 |
| NOTCH2 | notch 2 | 0.0255755 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0250731 |
| TENM1 | teneurin transmembrane protein 1 | 0.0250531 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0247648 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0245181 |
| PKM | pyruvate kinase, muscle | 0.0244152 |
| SMC4 | structural maintenance of chromosomes 4 | 0.024202 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0231699 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0225519 |
| ANLN | anillin, actin binding protein | 0.0215957 |
| PRELID2 | PRELI domain containing 2 | 0.0211977 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0199349 |
| CABIN1 | calcineurin binding protein 1 | 0.0197597 |
| RAD51B | RAD51 paralog B | 0.0197026 |
| CDK19 | cyclin-dependent kinase 19 | 0.0191257 |
| NLGN1 | neuroligin 1 | 0.0188581 |
| FAM13A | family with sequence similarity 13, member A | 0.0185684 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0184974 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0176521 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0169143 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0167953 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0157867 |
| MKRN1 | makorin ring finger protein 1 | 0.0157463 |
| WWOX | WW domain containing oxidoreductase | 0.0154254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0153123 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0148549 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0148332 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0148032 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0147499 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0146719 |
| TPM3 | tropomyosin 3 | 0.0144483 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0143503 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0142933 |
| SETD5 | SET domain containing 5 | 0.0142569 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.014253 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0142466 |
| FTL | ferritin, light polypeptide | 0.0141935 |
| RPS12 | ribosomal protein S12 | 0.0140013 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0139829 |
| HELZ | helicase with zinc finger | 0.0139421 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0136572 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0136193 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0135788 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0135393 |
| EEIG2 | EEIG family member 2 | 0.0135059 |
| XPO1 | exportin 1 | 0.0131042 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0129476 |
| KIF11 | kinesin family member 11 | 0.0127235 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0126916 |
| RPL3 | ribosomal protein L3 | 0.0126664 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0126396 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.0125995 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0125964 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0125491 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0124795 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0124637 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0124606 |
| ATXN1 | ataxin 1 | 0.0124353 |
| ASPH | aspartate beta-hydroxylase | 0.0123661 |
| NGLY1 | N-glycanase 1 | 0.0123575 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0123357 |
| PHF21A | PHD finger protein 21A | 0.0123158 |
| NEK7 | NIMA-related kinase 7 | 0.0123037 |
| ITGA6 | integrin, alpha 6 | 0.0122237 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0122059 |
| HYOU1 | hypoxia up-regulated 1 | 0.0121858 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0121535 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0121449 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0120725 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0119712 |
| HJURP | Holliday junction recognition protein | 0.011883 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0117802 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0115705 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0115252 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0115128 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0115115 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0115076 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0114915 |
| KIF5C | kinesin family member 5C | 0.0114425 |
| RNF150 | ring finger protein 150 | 0.0114354 |
| VMP1 | vacuole membrane protein 1 | 0.0114315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.213004 |
| FMN1 | formin 1 | -0.196731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.149972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142603 |
| NRG3 | neuregulin 3 | -0.121105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118373 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.116521 |
| FRMD4A | FERM domain containing 4A | -0.113875 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.099262 |
| VIM | vimentin | -0.0772427 |
| SQSTM1 | sequestosome 1 | -0.0686477 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0674959 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0641708 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511673 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0506261 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0488735 |
| CANX | calnexin | -0.0483865 |
| ACTG1 | actin gamma 1 | -0.0479775 |
| RPL35A | ribosomal protein L35a | -0.0467427 |
| PGK1 | phosphoglycerate kinase 1 | -0.0455121 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0448896 |
| CCND1 | cyclin D1 | -0.0427082 |
| UBC | ubiquitin C | -0.0422373 |
| RAB7A | RAB7A, member RAS oncogene family | -0.041953 |
| PMEL | premelanosome protein | -0.0412642 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0406548 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0396852 |
| GOLGA4 | golgin A4 | -0.0374957 |
| TXNRD1 | thioredoxin reductase 1 | -0.0362344 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0361923 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0347097 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0346019 |
| HDAC9 | histone deacetylase 9 | -0.0333242 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0330918 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0317458 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0315459 |
| FRMD5 | FERM domain containing 5 | -0.031079 |
| COMMD10 | COMM domain containing 10 | -0.0302804 |
| SP100 | SP100 nuclear antigen | -0.029579 |
| TNNC1 | troponin C type 1 (slow) | -0.0290272 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0283946 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.027858 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0276937 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0272562 |
| APOD | apolipoprotein D | -0.0269029 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0264924 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0262372 |
| RPS6 | ribosomal protein S6 | -0.0261458 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0257242 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0255448 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253472 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0251612 |
| RRBP1 | ribosome binding protein 1 | -0.0247015 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0245524 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.024306 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0242181 |
| KAZN | kazrin, periplakin interacting protein | -0.0238115 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0230632 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0229751 |
| RPS24 | ribosomal protein S24 | -0.0229084 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0228934 |
| CTTN | cortactin | -0.0227222 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0226125 |
| RACK1 | receptor for activated C kinase 1 | -0.0225856 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0224951 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0224854 |
| TCF20 | transcription factor 20 (AR1) | -0.0223561 |
| RIGI | RNA sensor RIG-I | -0.0223221 |
| RPL38 | ribosomal protein L38 | -0.0223152 |
| PRAME | preferentially expressed antigen in melanoma | -0.0220312 |
| NF1 | neurofibromin 1 | -0.0217758 |
| RPL8 | ribosomal protein L8 | -0.0217579 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0217334 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0212703 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211509 |
| RPS23 | ribosomal protein S23 | -0.0209994 |
| RPL34 | ribosomal protein L34 | -0.0209825 |
| TDRD3 | tudor domain containing 3 | -0.0208245 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.020696 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0201777 |
| HLA-B | major histocompatibility complex, class I, B | -0.0198996 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0194607 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0193903 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0189041 |
| CD63 | CD63 molecule | -0.018887 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0188705 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0188646 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0187115 |
| PLSCR1 | phospholipid scramblase 1 | -0.0185403 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0185077 |
| CA8 | carbonic anhydrase VIII | -0.0185035 |
| RPS21 | ribosomal protein S21 | -0.0183979 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0182121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0182048 |
| IER3 | immediate early response 3 | -0.0181979 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0180683 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0180661 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0178094 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0177794 |
| RPL32 | ribosomal protein L32 | -0.0177475 |
