| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.198376 |
| VCL | vinculin | 0.164514 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.163427 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.103239 |
| PDGFC | platelet derived growth factor C | 0.100025 |
| EGFR | epidermal growth factor receptor | 0.0935759 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0888948 |
| TJP1 | tight junction protein 1 | 0.0818676 |
| PYGB | phosphorylase, glycogen; brain | 0.0739665 |
| ZNF608 | zinc finger protein 608 | 0.0730795 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0726018 |
| PRELID2 | PRELI domain containing 2 | 0.0709424 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0686794 |
| HDAC9 | histone deacetylase 9 | 0.0675481 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0575589 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0574299 |
| RPS2 | ribosomal protein S2 | 0.0573913 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0558804 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0551244 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0548039 |
| NBEA | neurobeachin | 0.0508378 |
| DUSP4 | dual specificity phosphatase 4 | 0.0506096 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0494308 |
| PKM | pyruvate kinase, muscle | 0.0493461 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0486261 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0469096 |
| FLNB | filamin B, beta | 0.0441437 |
| SMYD3 | SET and MYND domain containing 3 | 0.0436779 |
| GLI3 | GLI family zinc finger 3 | 0.0433058 |
| TXNRD1 | thioredoxin reductase 1 | 0.0417196 |
| RPS12 | ribosomal protein S12 | 0.040751 |
| RPS3 | ribosomal protein S3 | 0.0405741 |
| ENO1 | enolase 1, (alpha) | 0.0403356 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0387006 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0386307 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0383834 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0382977 |
| RPL37A | ribosomal protein L37a | 0.0379468 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0365257 |
| MACROD2 | MACRO domain containing 2 | 0.0363744 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0363653 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0360897 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0360082 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.035891 |
| TBC1D22A | TBC1 domain family, member 22A | 0.035535 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0350233 |
| PHF3 | PHD finger protein 3 | 0.0343364 |
| CLTC | clathrin, heavy chain (Hc) | 0.0340765 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0332939 |
| ANXA3 | annexin A3 | 0.0328029 |
| LDHA | lactate dehydrogenase A | 0.0326399 |
| EXOC4 | exocyst complex component 4 | 0.0323539 |
| SFPQ | splicing factor proline/glutamine-rich | 0.031993 |
| APP | amyloid beta (A4) precursor protein | 0.0318228 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0312521 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0310237 |
| EFNA5 | ephrin-A5 | 0.0309849 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0309369 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0309221 |
| RBM26 | RNA binding motif protein 26 | 0.0308766 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0301814 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.029955 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.029521 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292981 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0291436 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0285458 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0285452 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.028383 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0281479 |
| EZR | ezrin | 0.0279468 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0276694 |
| FHIT | fragile histidine triad | 0.0276659 |
| NBAS | neuroblastoma amplified sequence | 0.0274287 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0270618 |
| RPL11 | ribosomal protein L11 | 0.0270398 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0268027 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0266201 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0264918 |
| TMEM65 | transmembrane protein 65 | 0.0261682 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0259786 |
| SEPTIN2 | septin 2 | 0.0258688 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.025699 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0256914 |
| NFIA | nuclear factor I/A | 0.0255371 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255302 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0255182 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0250249 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0249066 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0246215 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0244377 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0242834 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0242032 |
| FBLN2 | fibulin 2 | 0.0241368 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0238954 |
| GSE1 | Gse1 coiled-coil protein | 0.0236377 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0235764 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0235512 |
| YEATS2 | YEATS domain containing 2 | 0.023544 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0235336 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0233901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.373974 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.125741 |
| TMSB4X | thymosin beta 4, X-linked | -0.119827 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113765 |
| PTMA | prothymosin, alpha | -0.108221 |
| RPS6 | ribosomal protein S6 | -0.0927932 |
| RPL35A | ribosomal protein L35a | -0.0905309 |
| ACTG1 | actin gamma 1 | -0.0903613 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0712642 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0680285 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0538706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.049108 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0473256 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0453917 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0431218 |
| UBC | ubiquitin C | -0.0402666 |
| RPL34 | ribosomal protein L34 | -0.0397264 |
| RPL8 | ribosomal protein L8 | -0.0394945 |
| NOP58 | NOP58 ribonucleoprotein | -0.0394666 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0388622 |
| RPL32 | ribosomal protein L32 | -0.0379619 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0379088 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0371947 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0354064 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0354018 |
| RPS23 | ribosomal protein S23 | -0.0349968 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342572 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0340674 |
| RPS11 | ribosomal protein S11 | -0.0339567 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0321968 |
| AHNAK | AHNAK nucleoprotein | -0.0320459 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0319338 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0303156 |
| B2M | beta-2-microglobulin | -0.0302745 |
| S100A6 | S100 calcium binding protein A6 | -0.0299274 |
| CCNI | cyclin I | -0.0295739 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0293672 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0291786 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0290277 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0289709 |
| GOLGA4 | golgin A4 | -0.0285211 |
| AZIN1 | antizyme inhibitor 1 | -0.0285023 |
| DEK | DEK proto-oncogene | -0.027946 |
| YBX1 | Y box binding protein 1 | -0.0274175 |
| JUN | jun proto-oncogene | -0.0273985 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0271681 |
| TFG | TRK-fused gene | -0.0267124 |
| SEPTIN7 | septin 7 | -0.0264896 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0262751 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0257489 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0257467 |
| HLA-B | major histocompatibility complex, class I, B | -0.0254924 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0253283 |
| S100A10 | S100 calcium binding protein A10 | -0.0252859 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0251771 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0251503 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0249227 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0249194 |
| RPS15 | ribosomal protein S15 | -0.0248229 |
| RPS14 | ribosomal protein S14 | -0.0247229 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0245746 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0245171 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.024406 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0239082 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0236152 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0235549 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0235179 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0235022 |
| ZNF292 | zinc finger protein 292 | -0.0234837 |
| TXNIP | thioredoxin interacting protein | -0.0232923 |
| RPS27A | ribosomal protein S27a | -0.0229562 |
| CANX | calnexin | -0.02243 |
| FBXO11 | F-box protein 11 | -0.0218291 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0217489 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0216692 |
| H3-3B | H3.3 histone B | -0.0216187 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0216092 |
| FTL | ferritin, light polypeptide | -0.0216008 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | -0.0212001 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0211877 |
| HMGA1 | high mobility group AT-hook 1 | -0.021169 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0210445 |
| YY1 | YY1 transcription factor | -0.0210402 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0208571 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0205998 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0197898 |
| RPL14 | ribosomal protein L14 | -0.0196973 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0196347 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0195835 |
| POTEF | POTE ankyrin domain family, member F | -0.0195069 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0193709 |
| RPL4 | ribosomal protein L4 | -0.019328 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0193009 |
| CFDP1 | craniofacial development protein 1 | -0.0192812 |
| ATN1 | atrophin 1 | -0.0192329 |
| RPS29 | ribosomal protein S29 | -0.0192193 |
| YBX3 | Y box binding protein 3 | -0.0188318 |
| HDLBP | high density lipoprotein binding protein | -0.018809 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0187733 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0187713 |
