| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.140801 |
| FAM13A | family with sequence similarity 13, member A | 0.107197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0947172 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0925232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0845778 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0816144 |
| ATP13A3 | ATPase type 13A3 | 0.0802872 |
| MORF4L2 | mortality factor 4 like 2 | 0.0689467 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0641698 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.062524 |
| B2M | beta-2-microglobulin | 0.0621992 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0596166 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0590623 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0584725 |
| LOX | lysyl oxidase | 0.0581692 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0538262 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0528155 |
| ARRDC3 | arrestin domain containing 3 | 0.0516206 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0514316 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0491458 |
| TMSB10 | thymosin beta 10 | 0.0476118 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0475661 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0472962 |
| SQSTM1 | sequestosome 1 | 0.045433 |
| AFF4 | AF4/FMR2 family, member 4 | 0.044779 |
| RYBP | RING1 and YY1 binding protein | 0.0431962 |
| ZNF292 | zinc finger protein 292 | 0.0415302 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0410045 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0404889 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0402719 |
| SRP54 | signal recognition particle 54kDa | 0.0402617 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.040123 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0393638 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0390931 |
| SPAG9 | sperm associated antigen 9 | 0.037893 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0375899 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0374297 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0370479 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0364284 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0361224 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0358896 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.035386 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0334568 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.033342 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0327525 |
| TPX2 | TPX2, microtubule-associated | 0.0327273 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.03248 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0321474 |
| PCBP2 | poly(rC) binding protein 2 | 0.031934 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0319245 |
| NDRG1 | N-myc downstream regulated 1 | 0.03135 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0313356 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0310251 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0307989 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0304217 |
| APP | amyloid beta (A4) precursor protein | 0.0299245 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0297768 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0294642 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0293837 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0289348 |
| ENO1 | enolase 1, (alpha) | 0.028628 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0285729 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.028352 |
| ANLN | anillin, actin binding protein | 0.0281301 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0280892 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0280251 |
| IL6ST | interleukin 6 signal transducer | 0.0278796 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.027531 |
| KAZN | kazrin, periplakin interacting protein | 0.0273929 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0270886 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0270227 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0269273 |
| MYO10 | myosin X | 0.0268136 |
| ADM | adrenomedullin | 0.0267458 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0266196 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0265804 |
| GOLGA4 | golgin A4 | 0.0261859 |
| BRD4 | bromodomain containing 4 | 0.0259811 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0259661 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0259254 |
| HMGB2 | high mobility group box 2 | 0.0257239 |
| SEPTIN10 | septin 10 | 0.02544 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0253767 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0252481 |
| TMF1 | TATA element modulatory factor 1 | 0.0252178 |
| PRELID2 | PRELI domain containing 2 | 0.0246685 |
| AUTS2 | autism susceptibility candidate 2 | 0.0246508 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0246503 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0246391 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.024596 |
| YTHDC1 | YTH domain containing 1 | 0.0245504 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0245293 |
| CA12 | carbonic anhydrase XII | 0.0244913 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244697 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0244188 |
| RLF | rearranged L-myc fusion | 0.0243839 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0242359 |
| CDK19 | cyclin-dependent kinase 19 | 0.0239843 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0237019 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0236956 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.406237 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193059 |
| FN1 | fibronectin 1 | -0.119312 |
| POTEF | POTE ankyrin domain family, member F | -0.0981947 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0919996 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0877927 |
| ASPH | aspartate beta-hydroxylase | -0.0782526 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0593139 |
| GLIS3 | GLIS family zinc finger 3 | -0.0553785 |
| UBC | ubiquitin C | -0.0538831 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0476054 |
| COL1A1 | collagen, type I, alpha 1 | -0.0472735 |
| HMGA2 | high mobility group AT-hook 2 | -0.0454899 |
| SEPTIN7 | septin 7 | -0.0447286 |
| CDK6 | cyclin-dependent kinase 6 | -0.0438214 |
| TNS3 | tensin 3 | -0.0437642 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0437393 |
| HLA-C | major histocompatibility complex, class I, C | -0.0434595 |
| AHNAK | AHNAK nucleoprotein | -0.0426142 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0411401 |
| HLA-B | major histocompatibility complex, class I, B | -0.0407278 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0406613 |
| CALD1 | caldesmon 1 | -0.0394862 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0386921 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0368035 |
| VEGFA | vascular endothelial growth factor A | -0.0367979 |
| TPM4 | tropomyosin 4 | -0.034726 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0345757 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.034351 |
| CUX1 | cut-like homeobox 1 | -0.0337832 |
| CDH13 | cadherin 13 | -0.0336202 |
| TANK | TRAF family member-associated NFKB activator | -0.0333616 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0331705 |
| VEGFC | vascular endothelial growth factor C | -0.0330118 |
| ACTG1 | actin gamma 1 | -0.0320319 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0320086 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0319651 |
| CENPF | centromere protein F, 350/400kDa | -0.0313484 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0309876 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0305078 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0298112 |
| FAT1 | FAT atypical cadherin 1 | -0.0296074 |
| PKM | pyruvate kinase, muscle | -0.0282072 |
| NAV1 | neuron navigator 1 | -0.0277213 |
| CCND1 | cyclin D1 | -0.0276896 |
| CCNI | cyclin I | -0.0274636 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0274286 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0274094 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0273401 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0264369 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0260707 |
| RPL28 | ribosomal protein L28 | -0.0258696 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0256917 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0256208 |
| DSTN | destrin (actin depolymerizing factor) | -0.0255095 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0251566 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0250543 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0250538 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0249005 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0248561 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.02462 |
| MGLL | monoglyceride lipase | -0.0245928 |
| KIF2A | kinesin heavy chain member 2A | -0.0245869 |
| RNF216 | ring finger protein 216 | -0.0244987 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0244023 |
| MSN | moesin | -0.0243942 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0243517 |
| KLF12 | Kruppel-like factor 12 | -0.0243257 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0242879 |
| TMX3 | thioredoxin-related transmembrane protein 3 | -0.0241185 |
| RND3 | Rho family GTPase 3 | -0.0241023 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0240761 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.023961 |
| HDLBP | high density lipoprotein binding protein | -0.0239579 |
| ATXN1 | ataxin 1 | -0.023898 |
| INHBA | inhibin, beta A | -0.0238438 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0238402 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0238157 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0238138 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0237115 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0237082 |
| PTGES2 | prostaglandin E synthase 2 | -0.0237044 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0234028 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0233488 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0232458 |
| MTPN | myotrophin | -0.0232053 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0232017 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.0231095 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0230039 |
| EFNA5 | ephrin-A5 | -0.0229117 |
| AAK1 | AP2 associated kinase 1 | -0.0226711 |
| INTS6 | integrator complex subunit 6 | -0.0226588 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0224845 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0222291 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0222183 |
| MT1X | metallothionein 1X | -0.0221628 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.022051 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0220157 |
| WASF2 | WAS protein family, member 2 | -0.021953 |
| UBAP2 | ubiquitin associated protein 2 | -0.0218724 |
