| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.129282 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0642097 |
| AHR | aryl hydrocarbon receptor | 0.0640128 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0623385 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0569353 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0543971 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0543231 |
| TXNIP | thioredoxin interacting protein | 0.0496973 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0494844 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0485108 |
| SMOX | spermine oxidase | 0.0471565 |
| CENPF | centromere protein F, 350/400kDa | 0.0467664 |
| GOLGA4 | golgin A4 | 0.0454452 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0453544 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0435985 |
| RPS12 | ribosomal protein S12 | 0.0432012 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0426653 |
| OSMR | oncostatin M receptor | 0.0426652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0426455 |
| RTN4 | reticulon 4 | 0.0422844 |
| TXNRD1 | thioredoxin reductase 1 | 0.0414302 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0392188 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0388838 |
| WDR26 | WD repeat domain 26 | 0.0387647 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0386294 |
| SLTM | SAFB-like, transcription modulator | 0.038215 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0377134 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371846 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0367533 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0367395 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.036056 |
| CD109 | CD109 molecule | 0.0360383 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035138 |
| NEK7 | NIMA-related kinase 7 | 0.0347922 |
| NUP58 | nucleoporin 58 | 0.0347478 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0346484 |
| ZNF292 | zinc finger protein 292 | 0.0346433 |
| RUNX2 | runt-related transcription factor 2 | 0.034248 |
| FBXO32 | F-box protein 32 | 0.0341856 |
| MKI67 | marker of proliferation Ki-67 | 0.0339387 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337433 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333987 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0333799 |
| VEGFA | vascular endothelial growth factor A | 0.032986 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.032789 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0325469 |
| OGA | O-GlcNAcase | 0.032226 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0319671 |
| ETNK1 | ethanolamine kinase 1 | 0.0317624 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0314353 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0311856 |
| IL6ST | interleukin 6 signal transducer | 0.0311158 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0310674 |
| ITGB5 | integrin, beta 5 | 0.0308359 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306584 |
| SFXN1 | sideroflexin 1 | 0.0305739 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0303885 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0303745 |
| CDC73 | cell division cycle 73 | 0.0303371 |
| TMEM156 | transmembrane protein 156 | 0.0301873 |
| NRP1 | neuropilin 1 | 0.0299329 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0298903 |
| ENO1 | enolase 1, (alpha) | 0.0298014 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0295152 |
| ETV6 | ets variant 6 | 0.0294461 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.029212 |
| CAB39 | calcium binding protein 39 | 0.0291314 |
| CD44 | CD44 molecule (Indian blood group) | 0.0290443 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0289758 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0286025 |
| TMF1 | TATA element modulatory factor 1 | 0.0283588 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0279802 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0276663 |
| FAM13A | family with sequence similarity 13, member A | 0.0276328 |
| HDGF | hepatoma-derived growth factor | 0.0270919 |
| TPR | translocated promoter region, nuclear basket protein | 0.0269565 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0268731 |
| PLIN2 | perilipin 2 | 0.0268269 |
| TPM3 | tropomyosin 3 | 0.0267993 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0267675 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0267373 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.026658 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0264788 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0263334 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0263173 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0262628 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0260086 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0259164 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0258104 |
| VMP1 | vacuole membrane protein 1 | 0.0257605 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0257573 |
| SUCO | SUN domain containing ossification factor | 0.0256153 |
| PLPP6 | phospholipid phosphatase 6 | 0.0254633 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0250486 |
| COPA | coatomer protein complex, subunit alpha | 0.0249989 |
| RNF145 | ring finger protein 145 | 0.0249792 |
| RPS2 | ribosomal protein S2 | 0.0249652 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0248355 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0247716 |
| ANGPTL4 | angiopoietin-like 4 | 0.0245045 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.343289 |
| NRG1 | neuregulin 1 | -0.22054 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.193813 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.132063 |
| FN1 | fibronectin 1 | -0.123041 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.118425 |
| HLA-B | major histocompatibility complex, class I, B | -0.104211 |
| CANX | calnexin | -0.0928944 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0842691 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0808325 |
| PTMA | prothymosin, alpha | -0.0794604 |
| TMSB4X | thymosin beta 4, X-linked | -0.0756035 |
| RPL35A | ribosomal protein L35a | -0.0753623 |
| INTS6 | integrator complex subunit 6 | -0.0734551 |
| IER3 | immediate early response 3 | -0.0682686 |
| S100A10 | S100 calcium binding protein A10 | -0.0654022 |
| ACTG1 | actin gamma 1 | -0.0648342 |
| HMGA2 | high mobility group AT-hook 2 | -0.0622648 |
| ASPH | aspartate beta-hydroxylase | -0.0622527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0550636 |
| AHNAK | AHNAK nucleoprotein | -0.0540342 |
| H1-0 | H1.0 linker histone | -0.0527467 |
| UBC | ubiquitin C | -0.0526631 |
| AEBP2 | AE binding protein 2 | -0.0503639 |
| VCL | vinculin | -0.0495778 |
| TMSB10 | thymosin beta 10 | -0.0488482 |
| SQSTM1 | sequestosome 1 | -0.0456276 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0453311 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0417334 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0414095 |
| RPL34 | ribosomal protein L34 | -0.0389415 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0386548 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0381585 |
| RPS21 | ribosomal protein S21 | -0.0378555 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0373291 |
| RAI14 | retinoic acid induced 14 | -0.0370615 |
| RPS24 | ribosomal protein S24 | -0.0368136 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0367171 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0365117 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0344535 |
| FBXO11 | F-box protein 11 | -0.034213 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.033712 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0324598 |
| PALLD | palladin, cytoskeletal associated protein | -0.0314335 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0305776 |
| RPL38 | ribosomal protein L38 | -0.030344 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0299498 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0295483 |
| RPS11 | ribosomal protein S11 | -0.0294911 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293236 |
| RPS19 | ribosomal protein S19 | -0.0291509 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0290093 |
| FTL | ferritin, light polypeptide | -0.0288655 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0288181 |
| LRRC23 | leucine rich repeat containing 23 | -0.0281604 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0277789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0277388 |
| RPS6 | ribosomal protein S6 | -0.0273834 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0270032 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0269199 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0267901 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0266364 |
| EMP1 | epithelial membrane protein 1 | -0.0260879 |
| LMNA | lamin A/C | -0.0260735 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0260161 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0257635 |
| RPS23 | ribosomal protein S23 | -0.0257239 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0254817 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0253719 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0252676 |
| PGK1 | phosphoglycerate kinase 1 | -0.0246165 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0245243 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0242216 |
| RPL8 | ribosomal protein L8 | -0.0241592 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0241091 |
| RPS27A | ribosomal protein S27a | -0.0237055 |
| TENM4 | teneurin transmembrane protein 4 | -0.0236785 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0236492 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0236099 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.023471 |
| CADM1 | cell adhesion molecule 1 | -0.02347 |
| CD63 | CD63 molecule | -0.0233205 |
| ARF1 | ADP-ribosylation factor 1 | -0.0231435 |
| SDC4 | syndecan 4 | -0.0230275 |
| ATF3 | activating transcription factor 3 | -0.0229739 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0225573 |
| TGFB1 | transforming growth factor, beta 1 | -0.0222075 |
| RPL31 | ribosomal protein L31 | -0.0221605 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0219359 |
| CCDC138 | coiled-coil domain containing 138 | -0.0218818 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0215709 |
| COLEC11 | collectin sub-family member 11 | -0.0213758 |
| RPS15 | ribosomal protein S15 | -0.0213077 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0211752 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0210676 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.02097 |
| RPL12 | ribosomal protein L12 | -0.0207587 |
| TBCA | tubulin folding cofactor A | -0.0205487 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0205092 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0204954 |
